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HEALTH PROFESSIONAL · SOURCE READING

Treatment Options for Stage II and Node-Negative Stage III Soft Tissue Sarcoma

Source: Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: February 21, 2025 · Captured 2026-09-09.

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Context: Treatment of Stage II and Node-Negative Stage III Soft Tissue Sarcoma

Treatment options for stage II and node-negative stage III soft tissue sarcoma include:

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Surgery.

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Surgery with radiation therapy.

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Radiation therapy and/or chemotherapy followed by surgery.

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High-dose radiation therapy.

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For more information on surgery, radiation therapy, and chemotherapy, see the Treatment Option Overview for Soft Tissue Sarcoma section.

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Preserved source evidence · Not medical advice