HEALTH PROFESSIONAL · SOURCE READING

Surgery with neoadjuvant or adjuvant therapy

Source: Soft Tissue Sarcoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: February 21, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary.

Context: Treatment of Advanced Stage III (N1) Soft Tissue Sarcoma / Treatment Options for Advanced Stage III (N1) Soft Tissue Sarcoma

Neoadjuvant chemotherapy with or without radiation therapy or radiation therapy alone may be considered in selected cases where a limb-sparing surgery is advisable and/or there is a high probability of surgical resection with positive margins.[2-7]

Source links and citations

Adjuvant chemotherapy may be considered but is not known to improve overall survival.[1,8-11] Clinical trials should be considered when available.

Source links and citations

Publication references

Read the original reference and check its publication notices.

Preserved source evidence · Not medical advice