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← Hodgkin Lymphoma

FOR PATIENTS · SOURCE READING

Early Unfavorable

Source: Hodgkin Lymphoma Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: February 27, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Context: Stages of Hodgkin Lymphoma / Hodgkin lymphoma may be grouped for treatment as follows:

Early unfavorable Hodgkin lymphoma is stage I or stage II with one or more of the following risk factors that increase the chance that the cancer will come back after it is treated:

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Having a tumor in the chest that is larger than 1/3 of the width of the chest or is at least 10 centimeters.

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Having cancer in an organ other than the lymph nodes.

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Having a high sedimentation rate (in a sample of blood, the red blood cells settle to the bottom of the test tube more quickly than normal).

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Having three or more lymph nodes with cancer.

Having B symptoms (fever for no known reason, weight loss for no known reason, or drenching night sweats).

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Preserved source evidence · Independent clinical review pending · Not medical advice