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← Central Nervous System Tumors

FOR PATIENTS · SOURCE READING

Targeted therapy

Source: Adult Central Nervous System Tumors Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: January 5, 2024 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Context: Treatment Option Overview / The following types of treatment are used:

Targeted therapy is a type of treatment that uses drugs or other substances to identify and attack specific cancer cells.

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Monoclonal antibody therapy: Monoclonal antibodies are immune system proteins made in the laboratory to treat many diseases, including cancer. As a cancer treatment, these antibodies can attach to a specific target on cancer cells or other cells that may help cancer cells grow. The antibodies are able to then kill the cancer cells, block their growth, or keep them from spreading. Monoclonal antibodies are given by infusion. They may be used alone or to carry drugs, toxins, or radioactive material directly to cancer cells.Bevacizumab is a monoclonal antibody that binds to a protein called vascular endothelial growth factor (VEGF) and may prevent the growth of new blood vessels that tumors need to grow. Bevacizumab is used in the treatment of recurrent glioblastoma.

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Other types of targeted therapies are being studied for adult brain tumors, including tyrosine kinase inhibitors and new VEGF inhibitors.

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See Drugs Approved for Brain Tumors for more information.

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Preserved source evidence · Independent clinical review pending · Not medical advice