Skip to content
← Acute Myeloid Leukemia

FOR PATIENTS · SOURCE READING

Treatment of Acute Promyelocytic Leukemia

Source: Acute Myeloid Leukemia Treatment (PDQ®)–Patient Version, National Cancer Institute.

Source updated: May 16, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Treatment of newly diagnosed acute promyelocytic leukemia (APL) may include:

Source links and citations

all-trans retinoic acid (ATRA) plus arsenic trioxide (ATO), for low-risk to intermediate-risk disease

Source links and citations

ATRA plus combination chemotherapy, followed by ATO, for high-risk disease

Source links and citations

Learn more about these treatments in the Treatment Option Overview.

Source links and citations

Use our clinical trial search to find NCI-supported cancer clinical trials that are accepting patients. You can search for trials based on the type of cancer, the age of the patient, and where the trials are being done. General information about clinical trials is also available.

Source links and citations

Preserved source evidence · Independent clinical review pending · Not medical advice