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Treatment Options for Stage II Adrenocortical Carcinoma (ACC)

Source: Adrenocortical Carcinoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: December 13, 2024 · Captured 2026-09-09.

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Context: Treatment of Stage II Adrenocortical Carcinoma

Treatment options for stage II ACC include:

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stage II ACC

Complete surgical removal of the tumor is the treatment of choice for patients with stage II ACC. The long-term survival of patients with nonfunctioning tumors is comparable with that of patients with functioning tumors. The removal of regional lymph nodes that are not clinically enlarged is not indicated.

Adjuvant mitotane (under clinical evaluation).Adjuvant mitotane has shown some progression-free or disease-free survival advantage, no overall survival advantage.[1-3]

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Preserved source evidence · Not medical advice