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Treatment Options for Stage I Adrenocortical Carcinoma (ACC)

Source: Adrenocortical Carcinoma Treatment (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: December 13, 2024 · Captured 2026-09-09.

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Context: Treatment of Stage I Adrenocortical Carcinoma

Treatment options for stage I ACC include:

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stage I ACC

Complete surgical removal of the tumor is the treatment of choice for patients with stage I ACC. The long-term survival of patients with nonfunctioning tumors is comparable with that of patients with functioning tumors. The removal of regional lymph nodes that are not clinically enlarged is not indicated.

Adjuvant mitotane (under clinical evaluation).Adjuvant mitotane has shown some progression-free or disease-free survival advantage, but no overall survival advantage.[1-3]

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Preserved source evidence · Not medical advice