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NCT05740566 · BASELINE

Baseline characteristics

Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer · Source last updated 2026-01-05

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      255
    2. group Id
      BG001
      value
      254
    3. group Id
      BG002
      value
      509
    units
    Participants
groups
  1. description
    Participants were randomized to receive treatment according to the local SOC chemotherapy (lurbinectedin, topotecan, or amrubicin \[Japan only\]) in 21-day cycles.
    id
    BG000
    title
    Standard of Care (SOC)
  2. description
    Participants were randomized to receive tarlatamab as an IV infusion: A step dose of 1 mg on Cycle 1 Day 1 followed by the target dose 10 mg on Cycle 1 Day 8, Cycle 1 Day 15, and Q2W thereafter.
    id
    BG001
    title
    Tarlatamab 1 mg to 10 mg Q2W
  3. description
    Total of all reporting groups
    id
    BG002
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          9.2
          value
          64.2
        2. group Id
          BG001
          spread
          9.4
          value
          63.6
        3. group Id
          BG002
          spread
          9.3
          value
          63.9
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          86
        2. group Id
          BG001
          value
          72
        3. group Id
          BG002
          value
          158
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          169
        2. group Id
          BG001
          value
          182
        3. group Id
          BG002
          value
          351
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          11
        2. group Id
          BG001
          value
          12
        3. group Id
          BG002
          value
          23
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          128
        2. group Id
          BG001
          value
          140
        3. group Id
          BG002
          value
          268
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          116
        2. group Id
          BG001
          value
          102
        3. group Id
          BG002
          value
          218
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          107
        2. group Id
          BG001
          value
          97
        3. group Id
          BG002
          value
          204
        title
        Asian
      2. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          5
        title
        Black or African American
      3. measurements
        1. group Id
          BG000
          value
          139
        2. group Id
          BG001
          value
          152
        3. group Id
          BG002
          value
          291
        title
        White
      4. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          2
        title
        American Indian or Alaska Native
      5. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          4
        title
        Other
      6. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          3
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
population Description
The intent-to-treat (ITT) analysis set included all randomized participants.
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      255
    2. group Id
      BG001
      value
      254
    3. group Id
      BG002
      value
      509
    units
    Participants
groups
  1. description
    Participants were randomized to receive treatment according to the local SOC chemotherapy (lurbinectedin, topotecan, or amrubicin \[Japan only\]) in 21-day cycles.
    id
    BG000
    title
    Standard of Care (SOC)
  2. description
    Participants were randomized to receive tarlatamab as an IV infusion: A step dose of 1 mg on Cycle 1 Day 1 followed by the target dose 10 mg on Cycle 1 Day 8, Cycle 1 Day 15, and Q2W thereafter.
    id
    BG001
    title
    Tarlatamab 1 mg to 10 mg Q2W
  3. description
    Total of all reporting groups
    id
    BG002
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          9.2
          value
          64.2
        2. group Id
          BG001
          spread
          9.4
          value
          63.6
        3. group Id
          BG002
          spread
          9.3
          value
          63.9
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          86
        2. group Id
          BG001
          value
          72
        3. group Id
          BG002
          value
          158
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          169
        2. group Id
          BG001
          value
          182
        3. group Id
          BG002
          value
          351
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          11
        2. group Id
          BG001
          value
          12
        3. group Id
          BG002
          value
          23
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          128
        2. group Id
          BG001
          value
          140
        3. group Id
          BG002
          value
          268
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          116
        2. group Id
          BG001
          value
          102
        3. group Id
          BG002
          value
          218
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          107
        2. group Id
          BG001
          value
          97
        3. group Id
          BG002
          value
          204
        title
        Asian
      2. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          5
        title
        Black or African American
      3. measurements
        1. group Id
          BG000
          value
          139
        2. group Id
          BG001
          value
          152
        3. group Id
          BG002
          value
          291
        title
        White
      4. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          2
        title
        American Indian or Alaska Native
      5. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          4
        title
        Other
      6. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          3
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
population Description
The intent-to-treat (ITT) analysis set included all randomized participants.

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice