Baseline characteristics

A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77) · Source last updated 2026-08-26

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      251

   2. group Id

      BG001

      value

      126

   3. group Id

      BG002

      value

      377

   units

   Participants

groups

1. description

   Participants with treatment-naïve metastatic NSCLC receive 790 mg of Pembrolizumab Formulated With Berahyaluronidase Alfa via subcutaneous (SC) injection on Day 1 of each 6-week cycle for 18 cycles (up to approximately 108 weeks) in combination with platinum doublet chemotherapy.

   id

   BG000

   title

   Arm 1: Pembrolizumab Formulated With Berahyaluronidase Alfa + Platinum Doublet Chemotherapy

2. description

   Participants with treatment-naïve metastatic NSCLC receive 400 mg pembrolizumab intravenous (IV) infusion in combination with platinum doublet chemotherapy.

   id

   BG001

   title

   Arm 2: Pembrolizumab + Platinum Doublet Chemotherapy

3. description

   Total of all reporting groups

   id

   BG002

   title

   Total

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            spread

            9.6

            value

            64.7

         2. group Id

            BG001

            spread

            8.5

            value

            64.8

         3. group Id

            BG002

            spread

            9.2

            value

            64.8

   dispersion Type

   STANDARD_DEVIATION

   param Type

   MEAN

   title

   Age, Continuous

   unit Of Measure

   Years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            69

         2. group Id

            BG001

            value

            40

         3. group Id

            BG002

            value

            109

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            182

         2. group Id

            BG001

            value

            86

         3. group Id

            BG002

            value

            268

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            74

         2. group Id

            BG001

            value

            41

         3. group Id

            BG002

            value

            115

         title

         Hispanic or Latino

      2. measurements

         1. group Id

            BG000

            value

            177

         2. group Id

            BG001

            value

            85

         3. group Id

            BG002

            value

            262

         title

         Not Hispanic or Latino

      3. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            0

         title

         Unknown or Not Reported

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Ethnicity (NIH/OMB)

   unit Of Measure

   Participants

4. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            2

         2. group Id

            BG001

            value

            4

         3. group Id

            BG002

            value

            6

         title

         American Indian or Alaska Native

      2. measurements

         1. group Id

            BG000

            value

            74

         2. group Id

            BG001

            value

            36

         3. group Id

            BG002

            value

            110

         title

         Asian

      3. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            0

         title

         Native Hawaiian or Other Pacific Islander

      4. measurements

         1. group Id

            BG000

            value

            5

         2. group Id

            BG001

            value

            5

         3. group Id

            BG002

            value

            10

         title

         Black or African American

      5. measurements

         1. group Id

            BG000

            value

            158

         2. group Id

            BG001

            value

            78

         3. group Id

            BG002

            value

            236

         title

         White

      6. measurements

         1. group Id

            BG000

            value

            12

         2. group Id

            BG001

            value

            3

         3. group Id

            BG002

            value

            15

         title

         More than one race

      7. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            0

         title

         Unknown or Not Reported

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Race (NIH/OMB)

   unit Of Measure

   Participants

population Description

All randomized participants.

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice