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NCT05561920 · OUTCOME

The Results of Pharyngoesophageal Segment (PES) Vibration Analysed With the Biomechanical Model Obtained by High - Speed Video Endoscopy - Central Tendency and Dispersion - Open and Closed Phase Duration (%), Relative Shimmer and Relative Jitter

Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients · Source last updated 2026-03-31

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
MEDIAN
Unit
percentage (%)
Interval / dispersion
Inter-Quartile Range
Time frame
3 months

What was measured

The development of the biomechanical model of the PES aims to quantify non-stationary pharyngoesophageal vibrations and draw conclusions about the temporal characteristics of tissue stiffness, oscillating mass, pressure, and geometric distributions within the PES. The biomechanical model identifies mathematical dependencies and analyses extracted time signals of the PES opening and contours (i.e. the opening and closing of the vibrating mucosa of the PES). The PES waveform allows calculation of relative shimmer (%), relative jitter (%), and the duration of the open and closed phases (%), or the percentage of open or closed time of the PES, which is calculated from the PES waveform using the formulas listed in reference 5.

Groups in this outcome

The Results of PES Vibration Analysed With the Biomechanical Model - Central Tendency and Dispersion

Patients who have undergone total laryngectomy and completed minimal their 6-month period without disease after surgery and post-operative treatments such as radiotherapy or chemotherapy. The development of the biomechanical model of the PES in order to quantify non-stationary pharyngoesophageal vibrations and drawing conclusions on the temporal characteristics of tissue stiffness, oscillating mass, pressure, and geometric distributions within the PES. The biomechanical model identify mathematical dependencies and analyse extracted time signals of the PES opening and contours (i.e. the opening and closing of the vibrating mucosa of the PES).

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
The Results of PES Vibration Analysed With the Biomechanical Model - Central Tendency and Dispersion55

Reported measurements

Open phase duration of PES
Values in percentage (%) · Interval/dispersion: Inter-Quartile Range
GroupValueSpreadLowerUpperComment
The Results of PES Vibration Analysed With the Biomechanical Model - Central Tendency and Dispersion0.77Not reported0.680.83Not reported
Close phase duration of PES
Values in percentage (%) · Interval/dispersion: Inter-Quartile Range
GroupValueSpreadLowerUpperComment
The Results of PES Vibration Analysed With the Biomechanical Model - Central Tendency and Dispersion0.36Not reported0.330.42Not reported
Relative Shimmer
Values in percentage (%) · Interval/dispersion: Inter-Quartile Range
GroupValueSpreadLowerUpperComment
The Results of PES Vibration Analysed With the Biomechanical Model - Central Tendency and Dispersion0.99Not reported0.642.16Not reported
Relative Jitter
Values in percentage (%) · Interval/dispersion: Inter-Quartile Range
GroupValueSpreadLowerUpperComment
The Results of PES Vibration Analysed With the Biomechanical Model - Central Tendency and Dispersion2.94Not reported1.554.98Not reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        0.68
        upper Limit
        0.83
        value
        0.77
    title
    Open phase duration of PES
  2. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        0.33
        upper Limit
        0.42
        value
        0.36
    title
    Close phase duration of PES
  3. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        0.64
        upper Limit
        2.16
        value
        0.99
    title
    Relative Shimmer
  4. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        1.55
        upper Limit
        4.98
        value
        2.94
    title
    Relative Jitter
denoms
  1. counts
    1. group Id
      OG000
      value
      55
    units
    Participants
description
The development of the biomechanical model of the PES aims to quantify non-stationary pharyngoesophageal vibrations and draw conclusions about the temporal characteristics of tissue stiffness, oscillating mass, pressure, and geometric distributions within the PES. The biomechanical model identifies mathematical dependencies and analyses extracted time signals of the PES opening and contours (i.e. the opening and closing of the vibrating mucosa of the PES). The PES waveform allows calculation of relative shimmer (%), relative jitter (%), and the duration of the open and closed phases (%), or the percentage of open or closed time of the PES, which is calculated from the PES waveform using the formulas listed in reference 5.
dispersion Type
Inter-Quartile Range
groups
  1. description
    Patients who have undergone total laryngectomy and completed minimal their 6-month period without disease after surgery and post-operative treatments such as radiotherapy or chemotherapy. The development of the biomechanical model of the PES in order to quantify non-stationary pharyngoesophageal vibrations and drawing conclusions on the temporal characteristics of tissue stiffness, oscillating mass, pressure, and geometric distributions within the PES. The biomechanical model identify mathematical dependencies and analyse extracted time signals of the PES opening and contours (i.e. the opening and closing of the vibrating mucosa of the PES).
    id
    OG000
    title
    The Results of PES Vibration Analysed With the Biomechanical Model - Central Tendency and Dispersion
param Type
MEDIAN
reporting Status
POSTED
time Frame
3 months
title
The Results of Pharyngoesophageal Segment (PES) Vibration Analysed With the Biomechanical Model Obtained by High - Speed Video Endoscopy - Central Tendency and Dispersion - Open and Closed Phase Duration (%), Relative Shimmer and Relative Jitter
type
PRIMARY
unit Of Measure
percentage (%)

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Preserved source evidence · Not medical advice