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NCT05460273 · OUTCOME

Disease Control Rate (DCR), Assessed by Investigator

A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02) · Source last updated 2026-08-31

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
NUMBER
Unit
Percentage
Interval / dispersion
95% Confidence Interval
Time frame
TNBC cohort: from enrollment to 13 months post last subject dose with a median of 12 months follow up. NSCLC cohort: from enrollment to 20 months post last subject dose with a median of 16.7 months follow up.

What was measured

Duration of response is defined as the time from the date of first documented response (which is subsequently confirmed) until date of documented progression per RECIST 1.1, as assessed by investigator, or death due to any cause.

Analysis population: RES: Enrolled participants who received at least one dose of study intervention and had measurable disease at baseline by ICR.

Groups in this outcome

TNBC Cohort

Final Analysis with DCO on 06May2024

NSCLC Cohort

Final Analysis with DCO on 27Nov2024

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
TNBC Cohort77
NSCLC Cohort40

Reported measurements

Source class 1
Values in Percentage · Interval/dispersion: 95% Confidence Interval
GroupValueSpreadLowerUpperComment
TNBC Cohort76.6Not reported65.685.5Not reported
NSCLC Cohort85.0Not reported70.294.3Not reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        65.6
        upper Limit
        85.5
        value
        76.6
      2. group Id
        OG001
        lower Limit
        70.2
        upper Limit
        94.3
        value
        85.0
denoms
  1. counts
    1. group Id
      OG000
      value
      77
    2. group Id
      OG001
      value
      40
    units
    Participants
description
Duration of response is defined as the time from the date of first documented response (which is subsequently confirmed) until date of documented progression per RECIST 1.1, as assessed by investigator, or death due to any cause.
dispersion Type
95% Confidence Interval
groups
  1. description
    Final Analysis with DCO on 06May2024
    id
    OG000
    title
    TNBC Cohort
  2. description
    Final Analysis with DCO on 27Nov2024
    id
    OG001
    title
    NSCLC Cohort
param Type
NUMBER
population Description
RES: Enrolled participants who received at least one dose of study intervention and had measurable disease at baseline by ICR.
reporting Status
POSTED
time Frame
TNBC cohort: from enrollment to 13 months post last subject dose with a median of 12 months follow up. NSCLC cohort: from enrollment to 20 months post last subject dose with a median of 16.7 months follow up.
title
Disease Control Rate (DCR), Assessed by Investigator
type
SECONDARY
unit Of Measure
Percentage

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice