NCT05460273 · OUTCOME

Disease Control Rate (DCR), Assessed by ICR

A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02) · Source last updated 2026-08-31

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: NUMBER
Unit: Percentage
Interval / dispersion: 95% Confidence Interval
Time frame: TNBC cohort: from enrollment to 13 months post last subject dose with a median of 12 months follow up. NSCLC cohort: from enrollment to 20 months post last subject dose with a median of 16.7 months follow up.

What was measured

Disease control rate is defined as the percentage of participants who have a confirmed CR or PR or who have SD per RECIST 1.1, as assessed by ICR

Analysis population: RES: Enrolled participants who received at least one dose of study intervention and had measurable disease at baseline by ICR.

Groups in this outcome

TNBC Cohort

Final Analysis with DCO on 06May2024

NSCLC Cohort

Final Analysis with DCO on 27Nov2024

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
TNBC Cohort	77
NSCLC Cohort	40

Reported measurements

Source class 1

Values in Percentage · Interval/dispersion: 95% Confidence Interval
Group	Value	Spread	Lower	Upper	Comment
TNBC Cohort	72.7	Not reported	61.4	82.3	Not reported
NSCLC Cohort	85	Not reported	70.2	94.3	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
lower Limit
61.4
upper Limit
82.3
value
72.7
group Id
OG001
lower Limit
70.2
upper Limit
94.3
value
85

denoms

counts
group Id
OG000
value
77
group Id
OG001
value
40
units
Participants

description

Disease control rate is defined as the percentage of participants who have a confirmed CR or PR or who have SD per RECIST 1.1, as assessed by ICR

dispersion Type

95% Confidence Interval

groups

description
Final Analysis with DCO on 06May2024
id
OG000
title
TNBC Cohort
description
Final Analysis with DCO on 27Nov2024
id
OG001
title
NSCLC Cohort

param Type

NUMBER

population Description

RES: Enrolled participants who received at least one dose of study intervention and had measurable disease at baseline by ICR.

reporting Status

POSTED

time Frame

TNBC cohort: from enrollment to 13 months post last subject dose with a median of 12 months follow up. NSCLC cohort: from enrollment to 20 months post last subject dose with a median of 16.7 months follow up.

title

Disease Control Rate (DCR), Assessed by ICR

type

SECONDARY

unit Of Measure

Percentage

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice