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NCT05460273 · OUTCOME

Duration of Response (DoR), Assessed by Investigator

A Study of Dato-DXd in Chinese Patients With Advanced Non-Small Cell Lung Cancer, Triple-negative Breast Cancer and Other Solid Tumors (TROPION-PanTumor02) · Source last updated 2026-08-31

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
MEDIAN
Unit
months
Interval / dispersion
95% Confidence Interval
Time frame
TNBC cohort: from enrollment to 13 months post last subject dose with a median of 12 months follow up. NSCLC cohort: from enrollment to 20 months post last subject dose with a median of 16.7 months follow up.

What was measured

Duration of response is defined as the time from the date of first documented response (which is subsequently confirmed) until date of documented progression per RECIST 1.1, as assessed by investgator, or death due to any cause.

Analysis population: FAS: Enrolled participants who have received at least one dose of treatment. The analysis for DOR assessed by investigator was based on the responders in the FAS of each cohort.

Groups in this outcome

TNBC Cohort

Final Analysis with DCO on 06May2024

NSCLC Cohort

Final Analysis with DCO on 27Nov2024

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
TNBC Cohort25
NSCLC Cohort13

Reported measurements

Source class 1
Values in months · Interval/dispersion: 95% Confidence Interval
GroupValueSpreadLowerUpperComment
TNBC Cohort5.8Not reported4.018.4Not reported
NSCLC Cohort8.1Not reported4.211.2Not reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        4.01
        upper Limit
        8.4
        value
        5.8
      2. group Id
        OG001
        lower Limit
        4.2
        upper Limit
        11.2
        value
        8.1
denoms
  1. counts
    1. group Id
      OG000
      value
      25
    2. group Id
      OG001
      value
      13
    units
    Participants
description
Duration of response is defined as the time from the date of first documented response (which is subsequently confirmed) until date of documented progression per RECIST 1.1, as assessed by investgator, or death due to any cause.
dispersion Type
95% Confidence Interval
groups
  1. description
    Final Analysis with DCO on 06May2024
    id
    OG000
    title
    TNBC Cohort
  2. description
    Final Analysis with DCO on 27Nov2024
    id
    OG001
    title
    NSCLC Cohort
param Type
MEDIAN
population Description
FAS: Enrolled participants who have received at least one dose of treatment. The analysis for DOR assessed by investigator was based on the responders in the FAS of each cohort.
reporting Status
POSTED
time Frame
TNBC cohort: from enrollment to 13 months post last subject dose with a median of 12 months follow up. NSCLC cohort: from enrollment to 20 months post last subject dose with a median of 16.7 months follow up.
title
Duration of Response (DoR), Assessed by Investigator
type
SECONDARY
unit Of Measure
months

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice