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NCT05316701 · FLOW

Participant flow

Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies · Source last updated 2026-03-04

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups
  1. description
    Orca-T administered after myeloablative conditioning followed by single-agent tacrolimus
    id
    FG000
    title
    Orca-T
  2. description
    Unmanipulated allograft from peripheral blood of a matched donor after myeloablative conditioning followed by tacrolimus and methotrexate
    id
    FG001
    title
    Standard of Care
periods
  1. drop Withdraws
    1. reasons
      1. group Id
        FG000
        num Subjects
        0
      2. group Id
        FG001
        num Subjects
        1
      type
      Adverse Event
    2. reasons
      1. group Id
        FG000
        num Subjects
        3
      2. group Id
        FG001
        num Subjects
        9
      type
      Death
    3. reasons
      1. group Id
        FG000
        num Subjects
        1
      2. group Id
        FG001
        num Subjects
        0
      type
      Lost to Follow-up
    4. reasons
      1. group Id
        FG000
        num Subjects
        1
      2. group Id
        FG001
        num Subjects
        4
      type
      Physician Decision
    5. reasons
      1. group Id
        FG000
        num Subjects
        3
      2. group Id
        FG001
        num Subjects
        5
      type
      Withdrawal by Subject
    6. reasons
      1. group Id
        FG000
        num Subjects
        14
      2. group Id
        FG001
        num Subjects
        9
      type
      Progression/Relapse
    7. reasons
      1. group Id
        FG000
        num Subjects
        1
      2. group Id
        FG001
        num Subjects
        0
      type
      Received Standard of Care
    8. reasons
      1. group Id
        FG000
        num Subjects
        70
      2. group Id
        FG001
        num Subjects
        64
      type
      Ongoing
    milestones
    1. achievements
      1. group Id
        FG000
        num Subjects
        93
      2. group Id
        FG001
        num Subjects
        94
      type
      STARTED
    2. achievements
      1. group Id
        FG000
        num Subjects
        88
      2. group Id
        FG001
        num Subjects
        94
      type
      Participants Treated
    3. achievements
      1. group Id
        FG000
        num Subjects
        0
      2. group Id
        FG001
        num Subjects
        2
      type
      COMPLETED
    4. achievements
      1. group Id
        FG000
        num Subjects
        93
      2. group Id
        FG001
        num Subjects
        92
      type
      NOT COMPLETED
    title
    Overall Study
recruitment Details
187 participants were randomized to treatment from 19 study centers, of which 182 participants were treated
Complete source fields
groups
  1. description
    Orca-T administered after myeloablative conditioning followed by single-agent tacrolimus
    id
    FG000
    title
    Orca-T
  2. description
    Unmanipulated allograft from peripheral blood of a matched donor after myeloablative conditioning followed by tacrolimus and methotrexate
    id
    FG001
    title
    Standard of Care
periods
  1. drop Withdraws
    1. reasons
      1. group Id
        FG000
        num Subjects
        0
      2. group Id
        FG001
        num Subjects
        1
      type
      Adverse Event
    2. reasons
      1. group Id
        FG000
        num Subjects
        3
      2. group Id
        FG001
        num Subjects
        9
      type
      Death
    3. reasons
      1. group Id
        FG000
        num Subjects
        1
      2. group Id
        FG001
        num Subjects
        0
      type
      Lost to Follow-up
    4. reasons
      1. group Id
        FG000
        num Subjects
        1
      2. group Id
        FG001
        num Subjects
        4
      type
      Physician Decision
    5. reasons
      1. group Id
        FG000
        num Subjects
        3
      2. group Id
        FG001
        num Subjects
        5
      type
      Withdrawal by Subject
    6. reasons
      1. group Id
        FG000
        num Subjects
        14
      2. group Id
        FG001
        num Subjects
        9
      type
      Progression/Relapse
    7. reasons
      1. group Id
        FG000
        num Subjects
        1
      2. group Id
        FG001
        num Subjects
        0
      type
      Received Standard of Care
    8. reasons
      1. group Id
        FG000
        num Subjects
        70
      2. group Id
        FG001
        num Subjects
        64
      type
      Ongoing
    milestones
    1. achievements
      1. group Id
        FG000
        num Subjects
        93
      2. group Id
        FG001
        num Subjects
        94
      type
      STARTED
    2. achievements
      1. group Id
        FG000
        num Subjects
        88
      2. group Id
        FG001
        num Subjects
        94
      type
      Participants Treated
    3. achievements
      1. group Id
        FG000
        num Subjects
        0
      2. group Id
        FG001
        num Subjects
        2
      type
      COMPLETED
    4. achievements
      1. group Id
        FG000
        num Subjects
        93
      2. group Id
        FG001
        num Subjects
        92
      type
      NOT COMPLETED
    title
    Overall Study
recruitment Details
187 participants were randomized to treatment from 19 study centers, of which 182 participants were treated

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Preserved source evidence · Not medical advice