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NCT05198934 · BASELINE

Baseline characteristics

Sotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C Mutation · Source last updated 2026-07-22

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      54
    2. group Id
      BG001
      value
      53
    3. group Id
      BG002
      value
      53
    4. group Id
      BG003
      value
      160
    units
    Participants
groups
  1. description
    Participants received investigator's choice of trifluridine and tipiracil or regorafenib. Treatment continued until progressive disease, intolerance to treatment necessitating treatment discontinuation, need for other anticancer therapy, withdrawal of consent, or death.
    id
    BG000
    title
    Trifluridine and Tipiracil or Regorafenib
  2. description
    Participants received sotorasib 240 mg QD in combination with panitumumab. Treatment continued until progressive disease, intolerance to treatment necessitating treatment discontinuation, need for other anticancer therapy, withdrawal of consent, or death.
    id
    BG001
    title
    Sotorasib 240 mg + Panitumumab
  3. description
    Participants received sotorasib 960 mg QD in combination with panitumumab. Treatment continued until progressive disease, intolerance to treatment necessitating treatment discontinuation, need for other anticancer therapy, withdrawal of consent, or death.
    id
    BG002
    title
    Sotorasib 960 mg + Panitumumab
  4. description
    Total of all reporting groups
    id
    BG003
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          11.7
          value
          61.5
        2. group Id
          BG001
          spread
          11.9
          value
          58.2
        3. group Id
          BG002
          spread
          11.6
          value
          60.9
        4. group Id
          BG003
          spread
          11.7
          value
          60.2
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          30
        2. group Id
          BG001
          value
          27
        3. group Id
          BG002
          value
          24
        4. group Id
          BG003
          value
          81
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          24
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          29
        4. group Id
          BG003
          value
          79
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          8
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          12
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          45
        2. group Id
          BG001
          value
          53
        3. group Id
          BG002
          value
          47
        4. group Id
          BG003
          value
          145
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          3
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          12
        2. group Id
          BG001
          value
          22
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          40
        title
        Asian
      2. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        title
        Black or African American
      3. measurements
        1. group Id
          BG000
          value
          37
        2. group Id
          BG001
          value
          30
        3. group Id
          BG002
          value
          42
        4. group Id
          BG003
          value
          109
        title
        White
      4. measurements
        1. group Id
          BG000
          value
          5
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          5
        4. group Id
          BG003
          value
          10
        title
        Other/Unknown
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
population Description
Full analysis set (FAS) included all randomized participants.
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      54
    2. group Id
      BG001
      value
      53
    3. group Id
      BG002
      value
      53
    4. group Id
      BG003
      value
      160
    units
    Participants
groups
  1. description
    Participants received investigator's choice of trifluridine and tipiracil or regorafenib. Treatment continued until progressive disease, intolerance to treatment necessitating treatment discontinuation, need for other anticancer therapy, withdrawal of consent, or death.
    id
    BG000
    title
    Trifluridine and Tipiracil or Regorafenib
  2. description
    Participants received sotorasib 240 mg QD in combination with panitumumab. Treatment continued until progressive disease, intolerance to treatment necessitating treatment discontinuation, need for other anticancer therapy, withdrawal of consent, or death.
    id
    BG001
    title
    Sotorasib 240 mg + Panitumumab
  3. description
    Participants received sotorasib 960 mg QD in combination with panitumumab. Treatment continued until progressive disease, intolerance to treatment necessitating treatment discontinuation, need for other anticancer therapy, withdrawal of consent, or death.
    id
    BG002
    title
    Sotorasib 960 mg + Panitumumab
  4. description
    Total of all reporting groups
    id
    BG003
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          11.7
          value
          61.5
        2. group Id
          BG001
          spread
          11.9
          value
          58.2
        3. group Id
          BG002
          spread
          11.6
          value
          60.9
        4. group Id
          BG003
          spread
          11.7
          value
          60.2
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          30
        2. group Id
          BG001
          value
          27
        3. group Id
          BG002
          value
          24
        4. group Id
          BG003
          value
          81
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          24
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          29
        4. group Id
          BG003
          value
          79
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          8
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          12
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          45
        2. group Id
          BG001
          value
          53
        3. group Id
          BG002
          value
          47
        4. group Id
          BG003
          value
          145
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          3
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          12
        2. group Id
          BG001
          value
          22
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          40
        title
        Asian
      2. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        title
        Black or African American
      3. measurements
        1. group Id
          BG000
          value
          37
        2. group Id
          BG001
          value
          30
        3. group Id
          BG002
          value
          42
        4. group Id
          BG003
          value
          109
        title
        White
      4. measurements
        1. group Id
          BG000
          value
          5
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          5
        4. group Id
          BG003
          value
          10
        title
        Other/Unknown
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
population Description
Full analysis set (FAS) included all randomized participants.

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Independent clinical review pending · Not medical advice