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NCT04322539 · BASELINE

Baseline characteristics

A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer · Source last updated 2025-04-04

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      461
    2. group Id
      BG001
      value
      230
    3. group Id
      BG002
      value
      691
    units
    Participants
groups
  1. description
    Participants received 5 mg of fruquintinib oral capsule in combination with BSC once daily for 3 weeks of continuous dosing followed by a 1-week break during a treatment cycle (Each cycle length was 28 days).
    id
    BG000
    title
    Fruquintinib + BSC Group
  2. description
    Participants received placebo matched to fruquintinib oral capsule in combination with BSC once daily for 3 weeks of continuous dosing followed by a 1-week break during a treatment cycle (Each cycle length was 28 days).
    id
    BG001
    title
    Placebo + BSC Group
  3. description
    Total of all reporting groups
    id
    BG002
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          10.41
          value
          62.2
        2. group Id
          BG001
          spread
          9.67
          value
          62.4
        3. group Id
          BG002
          spread
          10.16
          value
          62.2
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          216
        2. group Id
          BG001
          value
          90
        3. group Id
          BG002
          value
          306
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          245
        2. group Id
          BG001
          value
          140
        3. group Id
          BG002
          value
          385
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          20
        2. group Id
          BG001
          value
          14
        3. group Id
          BG002
          value
          34
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          405
        2. group Id
          BG001
          value
          202
        3. group Id
          BG002
          value
          607
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          36
        2. group Id
          BG001
          value
          14
        3. group Id
          BG002
          value
          50
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          1
        title
        American Indian or Alaska Native
      2. measurements
        1. group Id
          BG000
          value
          43
        2. group Id
          BG001
          value
          18
        3. group Id
          BG002
          value
          61
        title
        Asian
      3. measurements
        1. group Id
          BG000
          value
          13
        2. group Id
          BG001
          value
          7
        3. group Id
          BG002
          value
          20
        title
        Black or African American
      4. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          5
        title
        Native Hawaiian or Other
      5. measurements
        1. group Id
          BG000
          value
          367
        2. group Id
          BG001
          value
          192
        3. group Id
          BG002
          value
          559
        title
        White
      6. measurements
        1. group Id
          BG000
          value
          5
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          7
        title
        Other
      7. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        title
        Multiple races
      8. measurements
        1. group Id
          BG000
          value
          28
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          36
        title
        Not reported/unknown
      title
      Race
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
population Description
Intent-to-Treat (ITT) population included all randomized participants.
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      461
    2. group Id
      BG001
      value
      230
    3. group Id
      BG002
      value
      691
    units
    Participants
groups
  1. description
    Participants received 5 mg of fruquintinib oral capsule in combination with BSC once daily for 3 weeks of continuous dosing followed by a 1-week break during a treatment cycle (Each cycle length was 28 days).
    id
    BG000
    title
    Fruquintinib + BSC Group
  2. description
    Participants received placebo matched to fruquintinib oral capsule in combination with BSC once daily for 3 weeks of continuous dosing followed by a 1-week break during a treatment cycle (Each cycle length was 28 days).
    id
    BG001
    title
    Placebo + BSC Group
  3. description
    Total of all reporting groups
    id
    BG002
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          10.41
          value
          62.2
        2. group Id
          BG001
          spread
          9.67
          value
          62.4
        3. group Id
          BG002
          spread
          10.16
          value
          62.2
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          216
        2. group Id
          BG001
          value
          90
        3. group Id
          BG002
          value
          306
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          245
        2. group Id
          BG001
          value
          140
        3. group Id
          BG002
          value
          385
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          20
        2. group Id
          BG001
          value
          14
        3. group Id
          BG002
          value
          34
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          405
        2. group Id
          BG001
          value
          202
        3. group Id
          BG002
          value
          607
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          36
        2. group Id
          BG001
          value
          14
        3. group Id
          BG002
          value
          50
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          1
        title
        American Indian or Alaska Native
      2. measurements
        1. group Id
          BG000
          value
          43
        2. group Id
          BG001
          value
          18
        3. group Id
          BG002
          value
          61
        title
        Asian
      3. measurements
        1. group Id
          BG000
          value
          13
        2. group Id
          BG001
          value
          7
        3. group Id
          BG002
          value
          20
        title
        Black or African American
      4. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          5
        title
        Native Hawaiian or Other
      5. measurements
        1. group Id
          BG000
          value
          367
        2. group Id
          BG001
          value
          192
        3. group Id
          BG002
          value
          559
        title
        White
      6. measurements
        1. group Id
          BG000
          value
          5
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          7
        title
        Other
      7. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        title
        Multiple races
      8. measurements
        1. group Id
          BG000
          value
          28
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          36
        title
        Not reported/unknown
      title
      Race
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
population Description
Intent-to-Treat (ITT) population included all randomized participants.

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Independent clinical review pending · Not medical advice