TriangleNCT04283773 · OUTCOME
Correlation Between P16 Cytoplasmic Score and FIGO Staging of MOGCTs.
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- MEAN
- Unit
- score on a scale
- Interval / dispersion
- 80% Confidence Interval
- Time frame
- After obtaining of results and collecting raw data , within 2 months.
What was measured
P16 cytoplasmic score is assessed by German quantitative scoring system by multiplying scores of intensity of staining ( 0= No , 1= weak , 2= moderate , 3 = strong ) in scores of intensity of staining ( 0 = less than 10% , 1= 11- 20 % , 2= 21-50 % , 3= 51-80% , 4= more than 80%) to induce final scores range between ( 0, 1,2,4,6,8,9 and 12). FIGO staging system for ovarian tumors between Stage I ( limited to ovaries) , II ( with pelvic extension) , III ( with peritoneal extension) and IV ( distant metastasis) , and it is reported from medical records of patients. One-way ANOVA was used to examine the Difference in Mean between groups. Post-hoc test with Bonferroni Correction was used for Pairwise comparisons . Data was expressed as mean (SD). A p-value \< 0.05 was considered significant.
Analysis population: P16 cytoplasmic score is assessed by German quantitative scoring system by multiplying scores of intensity of staining ( 0= No , 1= weak , 2= moderate , 3 = strong ) in scores of intensity of staining ( 0 = less than 10% , 1= 11- 20 % , 2= 21-50 % , 3= 51-80% , 4= more than 80%) to induce final scores range between ( 0, 1,2,4,6,8,9 and 12). FIGO staging for (malignant ovarian tumors only) is reported from medical records of patients . That explains why this measurement Arm/group 1( MOGCTs)only.
Groups in this outcome
Malignant Ovarian Germ Cell Tumors ( MOGCTs).
22 cases of malignant ovarian germ cell tumors ; include Dysgerminoma , yolk sac tumor and immature teratomas will be treated by anti P16 antibody
| Group | Source count |
|---|---|
| Malignant Ovarian Germ Cell Tumors ( MOGCTs). | 22 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Malignant Ovarian Germ Cell Tumors ( MOGCTs). | 11 | Not reported | 9.5 | 13.5 | Not reported |
Source statistical analyses
- ci Lower Limit
- 9.5
- ci Num Sides
- TWO_SIDED
- ci Pct Value
- 80
- ci Upper Limit
- 13
- dispersion Type
- STANDARD_DEVIATION
- dispersion Value
- 1.5
- group Description
- Correlation between P16 cytoplasmic score using German semi-quantitative system and FIGO staging of MOGCTs was done via One-way ANOVA was used to examine the Difference in Mean between groups. Post-hoc test with Bonferroni Correction was used for Pairwise comparisons .Data was expressed as mean (SD).
- group Ids
- OG000
- non Inferiority Comment
- One-way ANOVA was used to examine the Difference in Mean between groups. Post-hoc test with Bonferroni Correction was used for Pairwise comparisons .Data was expressed as mean (SD). P value is significant if less than 0.05.
- non Inferiority Type
- SUPERIORITY
- p Value
- 0.699
- p Value Comment
- One-way ANOVA was used to examine the Difference in Mean between groups. Post-hoc test with Bonferroni Correction was used for Pairwise comparisons .Data was expressed as mean (SD). P value is significant if less than 0.05.
- param Type
- Mean Difference (Final Values)
- param Value
- 11
- statistical Method
- ANOVA
Complete source fields
- analyses
- ci Lower Limit
- 9.5
- ci Num Sides
- TWO_SIDED
- ci Pct Value
- 80
- ci Upper Limit
- 13
- dispersion Type
- STANDARD_DEVIATION
- dispersion Value
- 1.5
- group Description
- Correlation between P16 cytoplasmic score using German semi-quantitative system and FIGO staging of MOGCTs was done via One-way ANOVA was used to examine the Difference in Mean between groups. Post-hoc test with Bonferroni Correction was used for Pairwise comparisons .Data was expressed as mean (SD).
- group Ids
- OG000
- non Inferiority Comment
- One-way ANOVA was used to examine the Difference in Mean between groups. Post-hoc test with Bonferroni Correction was used for Pairwise comparisons .Data was expressed as mean (SD). P value is significant if less than 0.05.
- non Inferiority Type
- SUPERIORITY
- p Value
- 0.699
- p Value Comment
- One-way ANOVA was used to examine the Difference in Mean between groups. Post-hoc test with Bonferroni Correction was used for Pairwise comparisons .Data was expressed as mean (SD). P value is significant if less than 0.05.
- param Type
- Mean Difference (Final Values)
- param Value
- 11
- statistical Method
- ANOVA
- classes
- categories
- measurements
- group Id
- OG000
- lower Limit
- 9.5
- upper Limit
- 13.5
- value
- 11
- denoms
- counts
- group Id
- OG000
- value
- 22
- units
- Participants
- description
- P16 cytoplasmic score is assessed by German quantitative scoring system by multiplying scores of intensity of staining ( 0= No , 1= weak , 2= moderate , 3 = strong ) in scores of intensity of staining ( 0 = less than 10% , 1= 11- 20 % , 2= 21-50 % , 3= 51-80% , 4= more than 80%) to induce final scores range between ( 0, 1,2,4,6,8,9 and 12). FIGO staging system for ovarian tumors between Stage I ( limited to ovaries) , II ( with pelvic extension) , III ( with peritoneal extension) and IV ( distant metastasis) , and it is reported from medical records of patients. One-way ANOVA was used to examine the Difference in Mean between groups. Post-hoc test with Bonferroni Correction was used for Pairwise comparisons . Data was expressed as mean (SD). A p-value \< 0.05 was considered significant.
- dispersion Type
- 80% Confidence Interval
- groups
- description
- 22 cases of malignant ovarian germ cell tumors ; include Dysgerminoma , yolk sac tumor and immature teratomas will be treated by anti P16 antibody
- id
- OG000
- title
- Malignant Ovarian Germ Cell Tumors ( MOGCTs).
- param Type
- MEAN
- population Description
- P16 cytoplasmic score is assessed by German quantitative scoring system by multiplying scores of intensity of staining ( 0= No , 1= weak , 2= moderate , 3 = strong ) in scores of intensity of staining ( 0 = less than 10% , 1= 11- 20 % , 2= 21-50 % , 3= 51-80% , 4= more than 80%) to induce final scores range between ( 0, 1,2,4,6,8,9 and 12). FIGO staging for (malignant ovarian tumors only) is reported from medical records of patients . That explains why this measurement Arm/group 1( MOGCTs)only.
- reporting Status
- POSTED
- time Frame
- After obtaining of results and collecting raw data , within 2 months.
- title
- Correlation Between P16 Cytoplasmic Score and FIGO Staging of MOGCTs.
- type
- SECONDARY
- unit Of Measure
- score on a scale
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Preserved source evidence · Not medical advice