NCT04269200 · BASELINE

Baseline characteristics

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer · Source last updated 2026-08-07

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

counts
group Id
BG000
value
270
group Id
BG001
value
267
group Id
BG002
value
268
group Id
BG003
value
805
units
Participants

groups

description
Platinum-based chemotherapy (paclitaxel and carboplatin) Q3W for a maximum of 6 cycles with durvalumab placebo (IV) Q3W. Following completion of chemotherapy treatment, patients without objective disease progression received durvalumab placebo (IV) Q4W and olaparib placebo (tablets) bd orally as maintenance treatment until disease progression.
id
BG000
title
SoC (Global Cohort & China Cohort)
description
Platinum-based chemotherapy (paclitaxel and carboplatin) Q3W for a maximum of 6 cycles with 1120 mg durvalumab (IV) Q3W. Following completion of chemotherapy treatment, patients without objective disease progression received 1500 mg durvalumab (IV) Q4W with olaparib placebo (tablets) bd orally as maintenance treatment until disease progression.
id
BG001
title
SoC + Durvalumab (Global Cohort & China Cohort)
description
Platinum-based chemotherapy (paclitaxel and carboplatin) Q3W for a maximum of 6 cycles with 1120 mg durvalumab (IV) Q3W. Following completion of chemotherapy treatment, patients without objective disease progression received 1500 mg durvalumab (IV) Q4W with 300 mg olaparib (tablets) bd orally as maintenance treatment until disease progression.
id
BG002
title
SoC + Durvalumab + Olaparib (Global Cohort & China Cohort)
description
Total of all reporting groups
id
BG003
title
Total

measures

classes
categories
measurements
group Id
BG000
spread
10.36
value
62.1
group Id
BG001
spread
9.82
value
63.3
group Id
BG002
spread
9.90
value
62.4
group Id
BG003
spread
10.03
value
62.6
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
spread
8.73
value
58.3
group Id
BG001
spread
10.57
value
57.6
group Id
BG002
spread
8.41
value
59.3
group Id
BG003
spread
9.24
value
58.4
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
description
Age at Screening
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
population Description
The results are presented by Global cohort and by China cohort.
title
Age, Continuous
unit Of Measure
Years
classes
categories
measurements
group Id
BG000
value
124
group Id
BG001
value
122
group Id
BG002
value
135
group Id
BG003
value
381
title
<65 years
measurements
group Id
BG000
value
117
group Id
BG001
value
116
group Id
BG002
value
104
group Id
BG003
value
337
title
>=65 years
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
value
35
group Id
BG001
value
30
group Id
BG002
value
30
group Id
BG003
value
95
title
<65 years
measurements
group Id
BG000
value
9
group Id
BG001
value
13
group Id
BG002
value
12
group Id
BG003
value
34
title
>=65 years
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
param Type
COUNT_OF_PARTICIPANTS
population Description
The results are presented by Global cohort and by China cohort.
title
Age, Customized
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
title
Female
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
title
Female
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
param Type
COUNT_OF_PARTICIPANTS
population Description
The results are presented by Global cohort and by China cohort.
title
Sex/Gender, Customized
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
20
group Id
BG001
value
28
group Id
BG002
value
32
group Id
BG003
value
80
title
Hispanic or Latino
measurements
group Id
BG000
value
218
group Id
BG001
value
208
group Id
BG002
value
206
group Id
BG003
value
632
title
Not Hispanic or Latino
measurements
group Id
BG000
value
3
group Id
BG001
value
2
group Id
BG002
value
1
group Id
BG003
value
6
title
Unknown or Not Reported
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Hispanic or Latino
measurements
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
title
Not Hispanic or Latino
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Unknown or Not Reported
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
param Type
COUNT_OF_PARTICIPANTS
population Description
The results are presented by Global cohort and by China cohort.
title
Ethnicity (NIH/OMB)
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
143
group Id
BG001
value
136
group Id
BG002
value
133
group Id
BG003
value
412
title
White
measurements
group Id
BG000
value
73
group Id
BG001
value
72
group Id
BG002
value
70
group Id
BG003
value
215
title
Asian
measurements
group Id
BG000
value
10
group Id
BG001
value
11
group Id
BG002
value
14
group Id
BG003
value
35
title
Black or African American
measurements
group Id
BG000
value
10
group Id
BG001
value
8
group Id
BG002
value
12
group Id
BG003
value
30
title
Other
measurements
group Id
BG000
value
0
group Id
BG001
value
6
group Id
BG002
value
6
group Id
BG003
value
12
title
American Indian or Alaska Native
measurements
group Id
BG000
value
2
group Id
BG001
value
0
group Id
BG002
value
1
group Id
BG003
value
3
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
3
group Id
BG001
value
5
group Id
BG002
value
3
group Id
BG003
value
11
title
Not reported
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
White
measurements
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
title
Asian
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Black or African American
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Other
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
American Indian or Alaska Native
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Not reported
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
param Type
COUNT_OF_PARTICIPANTS
population Description
The results are presented by Global cohort and by China cohort.
title
Race/Ethnicity, Customized
unit Of Measure
Participants

population Description

Global cohort: 241 SoC, 238 SoC + Durvalumab, 239 SoC + Durvalumab + Olaparib China cohort: 44 SoC, 43 SoC + Durvalumab, 42 SoC + Durvalumab + Olaparib There were 42 patients included in both Global and China cohorts (15 SOC, 14 SoC + Durvalumab, 13 SoC + Durvalumab + Olaparib).

Complete source fields

denoms

counts
group Id
BG000
value
270
group Id
BG001
value
267
group Id
BG002
value
268
group Id
BG003
value
805
units
Participants

groups

description
Platinum-based chemotherapy (paclitaxel and carboplatin) Q3W for a maximum of 6 cycles with durvalumab placebo (IV) Q3W. Following completion of chemotherapy treatment, patients without objective disease progression received durvalumab placebo (IV) Q4W and olaparib placebo (tablets) bd orally as maintenance treatment until disease progression.
id
BG000
title
SoC (Global Cohort & China Cohort)
description
Platinum-based chemotherapy (paclitaxel and carboplatin) Q3W for a maximum of 6 cycles with 1120 mg durvalumab (IV) Q3W. Following completion of chemotherapy treatment, patients without objective disease progression received 1500 mg durvalumab (IV) Q4W with olaparib placebo (tablets) bd orally as maintenance treatment until disease progression.
id
BG001
title
SoC + Durvalumab (Global Cohort & China Cohort)
description
Platinum-based chemotherapy (paclitaxel and carboplatin) Q3W for a maximum of 6 cycles with 1120 mg durvalumab (IV) Q3W. Following completion of chemotherapy treatment, patients without objective disease progression received 1500 mg durvalumab (IV) Q4W with 300 mg olaparib (tablets) bd orally as maintenance treatment until disease progression.
id
BG002
title
SoC + Durvalumab + Olaparib (Global Cohort & China Cohort)
description
Total of all reporting groups
id
BG003
title
Total

measures

classes
categories
measurements
group Id
BG000
spread
10.36
value
62.1
group Id
BG001
spread
9.82
value
63.3
group Id
BG002
spread
9.90
value
62.4
group Id
BG003
spread
10.03
value
62.6
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
spread
8.73
value
58.3
group Id
BG001
spread
10.57
value
57.6
group Id
BG002
spread
8.41
value
59.3
group Id
BG003
spread
9.24
value
58.4
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
description
Age at Screening
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
population Description
The results are presented by Global cohort and by China cohort.
title
Age, Continuous
unit Of Measure
Years
classes
categories
measurements
group Id
BG000
value
124
group Id
BG001
value
122
group Id
BG002
value
135
group Id
BG003
value
381
title
<65 years
measurements
group Id
BG000
value
117
group Id
BG001
value
116
group Id
BG002
value
104
group Id
BG003
value
337
title
>=65 years
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
value
35
group Id
BG001
value
30
group Id
BG002
value
30
group Id
BG003
value
95
title
<65 years
measurements
group Id
BG000
value
9
group Id
BG001
value
13
group Id
BG002
value
12
group Id
BG003
value
34
title
>=65 years
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
param Type
COUNT_OF_PARTICIPANTS
population Description
The results are presented by Global cohort and by China cohort.
title
Age, Customized
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
title
Female
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
title
Female
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
param Type
COUNT_OF_PARTICIPANTS
population Description
The results are presented by Global cohort and by China cohort.
title
Sex/Gender, Customized
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
20
group Id
BG001
value
28
group Id
BG002
value
32
group Id
BG003
value
80
title
Hispanic or Latino
measurements
group Id
BG000
value
218
group Id
BG001
value
208
group Id
BG002
value
206
group Id
BG003
value
632
title
Not Hispanic or Latino
measurements
group Id
BG000
value
3
group Id
BG001
value
2
group Id
BG002
value
1
group Id
BG003
value
6
title
Unknown or Not Reported
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Hispanic or Latino
measurements
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
title
Not Hispanic or Latino
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Unknown or Not Reported
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
param Type
COUNT_OF_PARTICIPANTS
population Description
The results are presented by Global cohort and by China cohort.
title
Ethnicity (NIH/OMB)
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
143
group Id
BG001
value
136
group Id
BG002
value
133
group Id
BG003
value
412
title
White
measurements
group Id
BG000
value
73
group Id
BG001
value
72
group Id
BG002
value
70
group Id
BG003
value
215
title
Asian
measurements
group Id
BG000
value
10
group Id
BG001
value
11
group Id
BG002
value
14
group Id
BG003
value
35
title
Black or African American
measurements
group Id
BG000
value
10
group Id
BG001
value
8
group Id
BG002
value
12
group Id
BG003
value
30
title
Other
measurements
group Id
BG000
value
0
group Id
BG001
value
6
group Id
BG002
value
6
group Id
BG003
value
12
title
American Indian or Alaska Native
measurements
group Id
BG000
value
2
group Id
BG001
value
0
group Id
BG002
value
1
group Id
BG003
value
3
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
3
group Id
BG001
value
5
group Id
BG002
value
3
group Id
BG003
value
11
title
Not reported
denoms
counts
group Id
BG000
value
241
group Id
BG001
value
238
group Id
BG002
value
239
group Id
BG003
value
718
units
Participants
title
Global cohort
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
White
measurements
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
title
Asian
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Black or African American
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Other
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
American Indian or Alaska Native
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Not reported
denoms
counts
group Id
BG000
value
44
group Id
BG001
value
43
group Id
BG002
value
42
group Id
BG003
value
129
units
Participants
title
China cohort
param Type
COUNT_OF_PARTICIPANTS
population Description
The results are presented by Global cohort and by China cohort.
title
Race/Ethnicity, Customized
unit Of Measure
Participants

population Description

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice