Participant flow

A Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors. · Source last updated 2025-04-17

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups

1. description

   Patients who received doses at 25 mg once daily under fasted conditions.

   id

   FG000

   title

   Dose Escalation 25 mg QD

2. description

   Patients who received doses at 50 mg once daily under fasted conditions.

   id

   FG001

   title

   Dose Escalation 50 mg QD

3. description

   Patients who received doses at 100 mg once daily under fasted conditions.

   id

   FG002

   title

   Dose Escalation 100 mg QD

4. description

   Patients who received doses at 200 mg once daily under fasted conditions.

   id

   FG003

   title

   Dose Escalation 200 mg QD

5. description

   Patients who received 400 mg once daily under fasted conditions.

   id

   FG004

   title

   Dose Escalation 400 mg QD

6. description

   Patients who received 800 mg once daily under fasted conditions.

   id

   FG005

   title

   Dose Escalation 800 mg QD

7. description

   Patients who received 800 mg once daily under not fasted conditions.

   id

   FG006

   title

   Dose Escalation 800 mg QD Not Fasted

8. description

   Patients who received 1000 mg once daily under fasted condition.

   id

   FG007

   title

   Dose Escalation 1000 mg QD

9. description

   Patients who received 1200 mg once daily under fasted conditions.

   id

   FG008

   title

   Dose Escalation 1200 mg QD

10. description

    Patients who received 400 mg twice daily under not fasted conditions.

    id

    FG009

    title

    Dose Escalation 400 mg BID

11. description

    Patients who received 600 mg twice daily under not fasted conditions.

    id

    FG010

    title

    Dose Escalation 600 mg BID

12. description

    Patients who received 800 mg twice daily under fasted conditions.

    id

    FG011

    title

    Dose Escalation 800 mg BID

Show more (12 of 13)

periods

1. drop Withdraws

   1. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         1

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         1

      10. group Id

          FG009

          num Subjects

          0

      11. group Id

          FG010

          num Subjects

          2

      12. group Id

          FG011

          num Subjects

          1

      Show more (12 of 13)

      type

      Adverse Event

   2. reasons

      1. group Id

         FG000

         num Subjects

         1

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         2

      6. group Id

         FG005

         num Subjects

         7

      7. group Id

         FG006

         num Subjects

         2

      8. group Id

         FG007

         num Subjects

         2

      9. group Id

         FG008

         num Subjects

         1

      10. group Id

          FG009

          num Subjects

          1

      11. group Id

          FG010

          num Subjects

          1

      12. group Id

          FG011

          num Subjects

          0

      Show more (12 of 13)

      type

      Death

   3. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         1

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         0

      10. group Id

          FG009

          num Subjects

          0

      11. group Id

          FG010

          num Subjects

          0

      12. group Id

          FG011

          num Subjects

          0

      Show more (12 of 13)

      type

      Physician Decision

   4. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         1

      4. group Id

         FG003

         num Subjects

         2

      5. group Id

         FG004

         num Subjects

         8

      6. group Id

         FG005

         num Subjects

         5

      7. group Id

         FG006

         num Subjects

         3

      8. group Id

         FG007

         num Subjects

         4

      9. group Id

         FG008

         num Subjects

         1

      10. group Id

          FG009

          num Subjects

          3

      11. group Id

          FG010

          num Subjects

          2

      12. group Id

          FG011

          num Subjects

          1

      Show more (12 of 13)

      type

      Progressive Disease

   5. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         1

      7. group Id

         FG006

         num Subjects

         2

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         1

      10. group Id

          FG009

          num Subjects

          0

      11. group Id

          FG010

          num Subjects

          0

      12. group Id

          FG011

          num Subjects

          2

      Show more (12 of 13)

      type

      Withdrawal by Subject

   6. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         1

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         1

      10. group Id

          FG009

          num Subjects

          0

      11. group Id

          FG010

          num Subjects

          0

      12. group Id

          FG011

          num Subjects

          1

      Show more (12 of 13)

      type

      Lost to Follow-up

   7. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         1

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         0

      10. group Id

          FG009

          num Subjects

          0

      11. group Id

          FG010

          num Subjects

          0

      12. group Id

          FG011

          num Subjects

          0

      Show more (12 of 13)

      type

      Started new therapy

   8. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         3

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         0

      10. group Id

          FG009

          num Subjects

          0

      11. group Id

          FG010

          num Subjects

          0

      12. group Id

          FG011

          num Subjects

          0

      Show more (12 of 13)

      type

      Study terminated early by sponsor

   9. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         1

      10. group Id

          FG009

          num Subjects

          0

      11. group Id

          FG010

          num Subjects

          0

      12. group Id

          FG011

          num Subjects

          0

      Show more (12 of 13)

      type

      Other

   milestones

   1. achievements

      1. group Id

         FG000

         num Subjects

         1

      2. group Id

         FG001

         num Subjects

         1

      3. group Id

         FG002

         num Subjects

         1

      4. group Id

         FG003

         num Subjects

         2

      5. group Id

         FG004

         num Subjects

         10

      6. group Id

         FG005

         num Subjects

         18

      7. group Id

         FG006

         num Subjects

         13

      8. group Id

         FG007

         num Subjects

         7

      9. group Id

         FG008

         num Subjects

         6

      10. group Id

          FG009

          num Subjects

          4

      11. group Id

          FG010

          num Subjects

          6

      12. group Id

          FG011

          num Subjects

          5

      Show more (12 of 13)

      type

      STARTED

   2. achievements

      1. comment

         Study was discontinued prematurely

         group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         2

      7. group Id

         FG006

         num Subjects

         3

      8. group Id

         FG007

         num Subjects

         1

      9. group Id

         FG008

         num Subjects

         0

      10. group Id

          FG009

          num Subjects

          0

      11. group Id

          FG010

          num Subjects

          1

      12. group Id

          FG011

          num Subjects

          0

      Show more (12 of 13)

      type

      COMPLETED

   3. achievements

      1. group Id

         FG000

         num Subjects

         1

      2. group Id

         FG001

         num Subjects

         1

      3. group Id

         FG002

         num Subjects

         1

      4. group Id

         FG003

         num Subjects

         2

      5. group Id

         FG004

         num Subjects

         10

      6. group Id

         FG005

         num Subjects

         16

      7. group Id

         FG006

         num Subjects

         10

      8. group Id

         FG007

         num Subjects

         6

      9. group Id

         FG008

         num Subjects

         6

      10. group Id

          FG009

          num Subjects

          4

      11. group Id

          FG010

          num Subjects

          5

      12. group Id

          FG011

          num Subjects

          5

      Show more (12 of 13)

      type

      NOT COMPLETED

   title

   Overall Study

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice