NCT03943667 · OUTCOME

Overall Survival

Gemcitabine and Paclitaxel vs Gemcitabine Alone After FOLFIRINOX Failure in Metastatic Pancreatic Ductal Adenocarcinoma · Source last updated 2026-01-15

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: MEDIAN
Unit: months
Interval / dispersion: 95% Confidence Interval
Time frame: Until death (life expectancy around 12 months)

What was measured

Time from the date of randomization to the date of death from any cause

Groups in this outcome

GEMPAX

Gemcitabine + Paclitaxel until progression Gemcitabine: 1000 mg/m² in IV infusion over 30-40 minutes at Day 1, 8 and 15 followed by one week of rest. Paclitaxel: 80 mg/m² in IV infusion over 60 minutes at Day 1, 8 and 15 followed by 1 week of rest.

Control

Gemcitabine alone until progression Gemcitabine: 1000 mg/m² in IV infusion over 30-40 minutes at Day 1, 8 and 15 followed by one week of rest.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
GEMPAX	140
Control	71

Reported measurements

Source class 1

Values in months · Interval/dispersion: 95% Confidence Interval
Group	Value	Spread	Lower	Upper	Comment
GEMPAX	6.4	Not reported	5.2	7.4	Not reported
Control	5.9	Not reported	4.6	6.9	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
lower Limit
5.2
upper Limit
7.4
value
6.4
group Id
OG001
lower Limit
4.6
upper Limit
6.9
value
5.9

denoms

counts
group Id
OG000
value
140
group Id
OG001
value
71
units
Participants

description

Time from the date of randomization to the date of death from any cause

dispersion Type

95% Confidence Interval

groups

description
Gemcitabine + Paclitaxel until progression Gemcitabine: 1000 mg/m² in IV infusion over 30-40 minutes at Day 1, 8 and 15 followed by one week of rest. Paclitaxel: 80 mg/m² in IV infusion over 60 minutes at Day 1, 8 and 15 followed by 1 week of rest.
id
OG000
title
GEMPAX
description
Gemcitabine alone until progression Gemcitabine: 1000 mg/m² in IV infusion over 30-40 minutes at Day 1, 8 and 15 followed by one week of rest.
id
OG001
title
Control

param Type

MEDIAN

reporting Status

POSTED

time Frame

Until death (life expectancy around 12 months)

title

Overall Survival

type

PRIMARY

unit Of Measure

months

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice