NCT03849651 · OUTCOME

One-year Event Free Survival (EFS) After Completion of the Protocol

TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies · Source last updated 2026-07-22

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: NUMBER
Unit: percentage of participants
Interval / dispersion: 95% Confidence Interval
Time frame: One year after receiving transplant

What was measured

Kaplan-Meier estimate of the percentage of being alive and relapse free one year after the date of transplant. (Events=relapse, death)

Analysis population: Patients who met eligibility criteria and received transplant.

Groups in this outcome

All Transplant Participants

Patients who met eligibility criteria and received transplant.

Dose 1

Patients who met eligibility criteria, received transplant, and received 1x10\^5 cells/kg

Dose 2

Patients who met eligibility criteria, received transplant, and received 1x10\^6 cells/kg

Dose 3

Patients who met eligibility criteria, received transplant, and received 1x10\^7 cells/kg

Phase 2

Patients who met eligibility criteria, received transplant, and were assigned the MED dose of 1x10\^7 cells/kg

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
All Transplant Participants	69
Dose 1	9
Dose 2	10
Dose 3	10
Phase 2	40

Reported measurements

Source class 1

Values in percentage of participants · Interval/dispersion: 95% Confidence Interval
Group	Value	Spread	Lower	Upper	Comment
All Transplant Participants	73.9	Not reported	61.8	82.7	Not reported
Dose 1	66.7	Not reported	28.2	87.8	Not reported
Dose 2	60.0	Not reported	25.3	82.7	Not reported
Dose 3	70.0	Not reported	32.9	89.2	Not reported
Phase 2	80.0	Not reported	64.0	89.5	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
lower Limit
61.8
upper Limit
82.7
value
73.9
group Id
OG001
lower Limit
28.2
upper Limit
87.8
value
66.7
group Id
OG002
lower Limit
25.3
upper Limit
82.7
value
60.0
group Id
OG003
lower Limit
32.9
upper Limit
89.2
value
70.0
group Id
OG004
lower Limit
64.0
upper Limit
89.5
value
80.0

denoms

counts
group Id
OG000
value
69
group Id
OG001
value
9
group Id
OG002
value
10
group Id
OG003
value
10
group Id
OG004
value
40
units
Participants

description

Kaplan-Meier estimate of the percentage of being alive and relapse free one year after the date of transplant. (Events=relapse, death)

dispersion Type

95% Confidence Interval

groups

description
Patients who met eligibility criteria and received transplant.
id
OG000
title
All Transplant Participants
description
Patients who met eligibility criteria, received transplant, and received 1x10\^5 cells/kg
id
OG001
title
Dose 1
description
Patients who met eligibility criteria, received transplant, and received 1x10\^6 cells/kg
id
OG002
title
Dose 2
description
Patients who met eligibility criteria, received transplant, and received 1x10\^7 cells/kg
id
OG003
title
Dose 3
description
Patients who met eligibility criteria, received transplant, and were assigned the MED dose of 1x10\^7 cells/kg
id
OG004
title
Phase 2

param Type

NUMBER

population Description

Patients who met eligibility criteria and received transplant.

reporting Status

POSTED

time Frame

One year after receiving transplant

title

One-year Event Free Survival (EFS) After Completion of the Protocol

type

PRIMARY

unit Of Measure

percentage of participants

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice