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NCT03735121 · OUTCOME

Part 2: Percentage of Health Care Professionals (HCPs) by Their Response to Question 2 of HCP SC Versus IV Perspective Questionnaire

A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer · Source last updated 2025-12-05

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
NUMBER
Unit
percentage of HCPs
Interval / dispersion
Not reported
Time frame
After HCP has completed administering at least 3 doses of atezolizumab SC and IV across all participants in Part 2 (Up to approximately 48 months)

What was measured

The HCP SC versus IV Perspective Questionnaire consisted of five items evaluating the number of atezolizumab SC and IV administrations done, convenience, potential time savings, and overall satisfaction with atezolizumab SC and atezolizumab IV, as well as reasons for HCP-reported satisfaction or dissatisfaction. HCPs who administered at least three doses of atezolizumab as an IV infusion and as a SC injection across all participants in Part 2 of this study responded to this questionnaire, of which question 2 is being reported here: Question 2: Which formulation of atezolizumab (SC or IV) do you think is more convenient for you? Responses to this question are reported in the data table. HCPs were allowed to complete the questionnaire until the last participant completed their assessments (duration between the 'first participant in \[FPI\]' date to 'last participant last visit \[LPLV\]' for Part 2).

Analysis population: Overall number analyzed included HCPs who completed Question 2 of the questionnaire.

Groups in this outcome

Part 2: Atezolizumab IV/Atezolizumab SC

Participants received atezolizumab, 1200 mg, as an IV infusion, Q3W, or atezolizumab, 1875 mg, co-formulated with rHuPH20, as SC injection, on Day 1 of each cycle (1 cycle=21 days) until PD, loss of clinical benefit, or unacceptable toxicity. HCPs who administered the IV or SC formulations completed the HCP SC versus IV Perspective Questionnaire.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Part 2: Atezolizumab IV/Atezolizumab SC50

Reported measurements

Atezolizumab SC is much more convenient
Values in percentage of HCPs · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Part 2: Atezolizumab IV/Atezolizumab SC24.0Not reportedNot reportedNot reportedNot reported
Atezolizumab SC is a little more convenient
Values in percentage of HCPs · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Part 2: Atezolizumab IV/Atezolizumab SC16.0Not reportedNot reportedNot reportedNot reported
Both formulations are equally convenient
Values in percentage of HCPs · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Part 2: Atezolizumab IV/Atezolizumab SC26.0Not reportedNot reportedNot reportedNot reported
Atezolizumab IV is a little more convenient
Values in percentage of HCPs · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Part 2: Atezolizumab IV/Atezolizumab SC12.0Not reportedNot reportedNot reportedNot reported
Atezolizumab IV is much more convenient
Values in percentage of HCPs · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
Part 2: Atezolizumab IV/Atezolizumab SC22.0Not reportedNot reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        value
        24.0
    title
    Atezolizumab SC is much more convenient
  2. categories
    1. measurements
      1. group Id
        OG000
        value
        16.0
    title
    Atezolizumab SC is a little more convenient
  3. categories
    1. measurements
      1. group Id
        OG000
        value
        26.0
    title
    Both formulations are equally convenient
  4. categories
    1. measurements
      1. group Id
        OG000
        value
        12.0
    title
    Atezolizumab IV is a little more convenient
  5. categories
    1. measurements
      1. group Id
        OG000
        value
        22.0
    title
    Atezolizumab IV is much more convenient
denoms
  1. counts
    1. group Id
      OG000
      value
      50
    units
    Participants
description
The HCP SC versus IV Perspective Questionnaire consisted of five items evaluating the number of atezolizumab SC and IV administrations done, convenience, potential time savings, and overall satisfaction with atezolizumab SC and atezolizumab IV, as well as reasons for HCP-reported satisfaction or dissatisfaction. HCPs who administered at least three doses of atezolizumab as an IV infusion and as a SC injection across all participants in Part 2 of this study responded to this questionnaire, of which question 2 is being reported here: Question 2: Which formulation of atezolizumab (SC or IV) do you think is more convenient for you? Responses to this question are reported in the data table. HCPs were allowed to complete the questionnaire until the last participant completed their assessments (duration between the 'first participant in \[FPI\]' date to 'last participant last visit \[LPLV\]' for Part 2).
groups
  1. description
    Participants received atezolizumab, 1200 mg, as an IV infusion, Q3W, or atezolizumab, 1875 mg, co-formulated with rHuPH20, as SC injection, on Day 1 of each cycle (1 cycle=21 days) until PD, loss of clinical benefit, or unacceptable toxicity. HCPs who administered the IV or SC formulations completed the HCP SC versus IV Perspective Questionnaire.
    id
    OG000
    title
    Part 2: Atezolizumab IV/Atezolizumab SC
param Type
NUMBER
population Description
Overall number analyzed included HCPs who completed Question 2 of the questionnaire.
reporting Status
POSTED
time Frame
After HCP has completed administering at least 3 doses of atezolizumab SC and IV across all participants in Part 2 (Up to approximately 48 months)
title
Part 2: Percentage of Health Care Professionals (HCPs) by Their Response to Question 2 of HCP SC Versus IV Perspective Questionnaire
type
SECONDARY
unit Of Measure
percentage of HCPs

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Preserved source evidence · Not medical advice