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NCT03697109 · OUTCOME

Change in SBP and DBP During the OL Phase

A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome · Source last updated 2025-07-16

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
MEAN
Unit
mm Hg
Interval / dispersion
Standard Deviation
Time frame
Baseline and Week 22 (end of OL Phase)

What was measured

Blood pressure was measured by 24-hour ABPM.

Analysis population: The analysis population was patients in the mITT-OL Population who had HTN at Baseline.

Groups in this outcome

Relacorilant (OL Phase)

Patients will receive relacorilant increased sequentially from 100 mg once daily to a maximum dose of 400 mg once daily. Relacorilant: Relacorilant is supplied as 100 mg capsules for oral dosing.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Relacorilant (OL Phase)102

Reported measurements

Baseline SBP

Analysis denominator · Participants

GroupSource count
Relacorilant (OL Phase)101
Values in mm Hg · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Relacorilant (OL Phase)140.6610.66Not reportedNot reportedNot reported
Change from Baseline in SBP at Week 22

Analysis denominator · Participants

GroupSource count
Relacorilant (OL Phase)66
Values in mm Hg · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Relacorilant (OL Phase)-7.99.78Not reportedNot reportedNot reported
Baseline DBP

Analysis denominator · Participants

GroupSource count
Relacorilant (OL Phase)101
Values in mm Hg · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Relacorilant (OL Phase)88.97.20Not reportedNot reportedNot reported
Change from Baseline in DBP at Week 22

Analysis denominator · Participants

GroupSource count
Relacorilant (OL Phase)66
Values in mm Hg · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Relacorilant (OL Phase)-5.46.98Not reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        spread
        10.66
        value
        140.66
    denoms
    1. counts
      1. group Id
        OG000
        value
        101
      units
      Participants
    title
    Baseline SBP
  2. categories
    1. measurements
      1. group Id
        OG000
        spread
        9.78
        value
        -7.9
    denoms
    1. counts
      1. group Id
        OG000
        value
        66
      units
      Participants
    title
    Change from Baseline in SBP at Week 22
  3. categories
    1. measurements
      1. group Id
        OG000
        spread
        7.20
        value
        88.9
    denoms
    1. counts
      1. group Id
        OG000
        value
        101
      units
      Participants
    title
    Baseline DBP
  4. categories
    1. measurements
      1. group Id
        OG000
        spread
        6.98
        value
        -5.4
    denoms
    1. counts
      1. group Id
        OG000
        value
        66
      units
      Participants
    title
    Change from Baseline in DBP at Week 22
denoms
  1. counts
    1. group Id
      OG000
      value
      102
    units
    Participants
description
Blood pressure was measured by 24-hour ABPM.
dispersion Type
Standard Deviation
groups
  1. description
    Patients will receive relacorilant increased sequentially from 100 mg once daily to a maximum dose of 400 mg once daily. Relacorilant: Relacorilant is supplied as 100 mg capsules for oral dosing.
    id
    OG000
    title
    Relacorilant (OL Phase)
param Type
MEAN
population Description
The analysis population was patients in the mITT-OL Population who had HTN at Baseline.
reporting Status
POSTED
time Frame
Baseline and Week 22 (end of OL Phase)
title
Change in SBP and DBP During the OL Phase
type
OTHER_PRE_SPECIFIED
unit Of Measure
mm Hg

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice