NCT03697109 · OUTCOME

Change in 2-hour Plasma Glucose During the OL Phase

A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome · Source last updated 2025-07-16

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: MEAN
Unit: mmol/L
Interval / dispersion: Standard Deviation
Time frame: Baseline and Week 22 (end of OL Phase)

What was measured

Plasma glucose was measured using the 2-hour oGTT.

Analysis population: The analysis population was patients in the mITT-OL Population who had DM/IGT with or without HTN at Baseline.

Groups in this outcome

Relacorilant (OL Phase)

Patients will receive relacorilant increased sequentially from 100 mg once daily to a maximum dose of 400 mg once daily. Relacorilant: Relacorilant is supplied as 100 mg capsules for oral dosing.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
Relacorilant (OL Phase)	120

Reported measurements

Baseline oGTT

Analysis denominator · Participants

Group	Source count
Relacorilant (OL Phase)	119

Values in mmol/L · Interval/dispersion: Standard Deviation
Group	Value	Spread	Lower	Upper	Comment
Relacorilant (OL Phase)	14.370	4.9402	Not reported	Not reported	Not reported

Change from Baseline in oGTT at Week 22

Analysis denominator · Participants

Group	Source count
Relacorilant (OL Phase)	71

Values in mmol/L · Interval/dispersion: Standard Deviation
Group	Value	Spread	Lower	Upper	Comment
Relacorilant (OL Phase)	-2.117	4.6354	Not reported	Not reported	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
spread
4.9402
value
14.370
denoms
counts
group Id
OG000
value
119
units
Participants
title
Baseline oGTT
categories
measurements
group Id
OG000
spread
4.6354
value
-2.117
denoms
counts
group Id
OG000
value
71
units
Participants
title
Change from Baseline in oGTT at Week 22

denoms

counts
group Id
OG000
value
120
units
Participants

description

Plasma glucose was measured using the 2-hour oGTT.

dispersion Type

Standard Deviation

groups

description
Patients will receive relacorilant increased sequentially from 100 mg once daily to a maximum dose of 400 mg once daily. Relacorilant: Relacorilant is supplied as 100 mg capsules for oral dosing.
id
OG000
title
Relacorilant (OL Phase)

param Type

MEAN

population Description

The analysis population was patients in the mITT-OL Population who had DM/IGT with or without HTN at Baseline.

reporting Status

POSTED

time Frame

Baseline and Week 22 (end of OL Phase)

title

Change in 2-hour Plasma Glucose During the OL Phase

type

OTHER_PRE_SPECIFIED

unit Of Measure

mmol/L

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Preserved source evidence · Not medical advice