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NCT03654833 · BASELINE

Baseline characteristics

Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma · Source last updated 2026-08-17

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      26
    2. group Id
      BG001
      value
      26
    3. group Id
      BG002
      value
      26
    4. group Id
      BG003
      value
      26
    5. group Id
      BG004
      value
      26
    6. group Id
      BG005
      value
      130
    units
    Participants
groups
  1. description
    Rucaparib in DNA damage sensitive relapsed mesothelioma
    id
    BG000
    title
    MiST-1
  2. description
    Abemaciclib in p16INK4A negative mesothelioma
    id
    BG001
    title
    MiST-2
  3. description
    Pembrolizumab and bemcentinib in relapsed mesothelioma
    id
    BG002
    title
    MiST-3
  4. description
    Atezolizumab and Bevacizumab in relapsed mesothelioma
    id
    BG003
    title
    MiST-4
  5. description
    Dostarlimab and Niraparib in Patients with Platinum Sensitive Relapsed Mesothelioma
    id
    BG004
    title
    MiST-5
  6. description
    Total of all reporting groups
    id
    BG005
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          lower Limit
          60.0
          upper Limit
          71.0
          value
          66.5
        2. group Id
          BG001
          lower Limit
          64.0
          upper Limit
          74.0
          value
          67.5
        3. group Id
          BG002
          lower Limit
          69.0
          upper Limit
          75.0
          value
          72.5
        4. group Id
          BG003
          lower Limit
          67.0
          upper Limit
          74.0
          value
          68.0
        5. group Id
          BG004
          lower Limit
          68.0
          upper Limit
          74.0
          value
          69.5
        6. group Id
          BG005
          lower Limit
          64.0
          upper Limit
          74.0
          value
          69.0
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    dispersion Type
    INTER_QUARTILE_RANGE
    param Type
    MEDIAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          3
        3. group Id
          BG002
          value
          3
        4. group Id
          BG003
          value
          8
        5. group Id
          BG004
          value
          5
        6. group Id
          BG005
          value
          23
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          22
        2. group Id
          BG001
          value
          23
        3. group Id
          BG002
          value
          23
        4. group Id
          BG003
          value
          18
        5. group Id
          BG004
          value
          21
        6. group Id
          BG005
          value
          107
        title
        Male
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG005
          value
          0
      denoms
      1. counts
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    population Description
    Race and Ethnicity were not collected from any participant.
    title
    Race and Ethnicity Not Collected
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          21
        2. group Id
          BG001
          value
          21
        3. group Id
          BG002
          value
          23
        4. group Id
          BG003
          value
          20
        5. group Id
          BG004
          value
          21
        6. group Id
          BG005
          value
          106
        title
        Epithelioid
      2. measurements
        1. group Id
          BG000
          value
          5
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          14
        title
        Biphasic
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          6
        title
        Sarcomatoid
      4. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          4
        title
        NOS
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Mesothelioma subtype
    unit Of Measure
    Participants
  5. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          4
        6. group Id
          BG005
          value
          11
        title
        Smoker
      2. measurements
        1. group Id
          BG000
          value
          15
        2. group Id
          BG001
          value
          14
        3. group Id
          BG002
          value
          12
        4. group Id
          BG003
          value
          13
        5. group Id
          BG004
          value
          12
        6. group Id
          BG005
          value
          66
        title
        Non-smoker
      3. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          13
        4. group Id
          BG003
          value
          11
        5. group Id
          BG004
          value
          10
        6. group Id
          BG005
          value
          53
        title
        Ex-smoker
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Smoking status
    unit Of Measure
    Participants
  6. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          15
        2. group Id
          BG001
          value
          20
        3. group Id
          BG002
          value
          20
        4. group Id
          BG003
          value
          16
        5. group Id
          BG004
          value
          18
        6. group Id
          BG005
          value
          89
        title
        Yes
      2. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          6
        title
        No
      3. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          8
        5. group Id
          BG004
          value
          8
        6. group Id
          BG005
          value
          35
        title
        Unknown
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    title
    History of asbestos
    unit Of Measure
    Participants
  7. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          4
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          20
        title
        Zero
      2. measurements
        1. group Id
          BG000
          value
          22
        2. group Id
          BG001
          value
          22
        3. group Id
          BG002
          value
          20
        4. group Id
          BG003
          value
          22
        5. group Id
          BG004
          value
          24
        6. group Id
          BG005
          value
          110
        title
        One
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    PS 0 would be expected to have better outcomes than PS 1 Grade=0: Fully active, able to carry on all pre-disease performance without restriction Grade=1: Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work Original Reference: Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982 Dec;5(6):649-655. PMID: 7165009.
    param Type
    COUNT_OF_PARTICIPANTS
    title
    ECOG status
    unit Of Measure
    Participants
  8. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          25
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          25
        4. group Id
          BG003
          value
          24
        5. group Id
          BG004
          value
          24
        6. group Id
          BG005
          value
          124
        title
        Thoracic
      2. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          4
        title
        Abdominal
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          1
        title
        Missing
      4. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          1
        title
        Pelvis
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    Primary tumour site is : "the original location where mesothelioma was diagnosed". There is no clear prognostic difference between Thorax/Abdomen/Pelvis as such and do not represent stages or grades.
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Primary Tumour site
    unit Of Measure
    Participants
  9. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          5
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          6
        6. group Id
          BG005
          value
          20
        title
        T1
      2. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          9
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          4
        6. group Id
          BG005
          value
          21
        title
        T2
      3. measurements
        1. group Id
          BG000
          value
          10
        2. group Id
          BG001
          value
          5
        3. group Id
          BG002
          value
          9
        4. group Id
          BG003
          value
          7
        5. group Id
          BG004
          value
          6
        6. group Id
          BG005
          value
          37
        title
        T3
      4. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          13
        5. group Id
          BG004
          value
          8
        6. group Id
          BG005
          value
          44
        title
        T4
      5. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          2
        title
        Missing
      6. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          3
        title
        TX
      7. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          3
        title
        Unobtainable
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    The 7th edition of TNM staging was used. Larger number of T (tumour) would be worse outcomes Reference: The 7th lung cancer TNM classification and staging system: Review of the changes and implications - PMC
    param Type
    COUNT_OF_PARTICIPANTS
    title
    T-stage
    unit Of Measure
    Participants
  10. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          16
        4. group Id
          BG003
          value
          11
        5. group Id
          BG004
          value
          13
        6. group Id
          BG005
          value
          59
        title
        N0
      2. measurements
        1. group Id
          BG000
          value
          6
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          6
        5. group Id
          BG004
          value
          7
        6. group Id
          BG005
          value
          33
        title
        N1
      3. measurements
        1. group Id
          BG000
          value
          7
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          8
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          27
        title
        N2
      4. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          6
        title
        N3
      5. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          2
        title
        Missing
      6. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          3
        title
        Unobtainable
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    The 7th edition of TNM staging was used. Larger number of N (nodes) would be worse outcomes Reference: The 7th lung cancer TNM classification and staging system: Review of the changes and implications - PMC
    param Type
    COUNT_OF_PARTICIPANTS
    title
    N-stage
    unit Of Measure
    Participants
  11. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          21
        2. group Id
          BG001
          value
          21
        3. group Id
          BG002
          value
          19
        4. group Id
          BG003
          value
          20
        5. group Id
          BG004
          value
          16
        6. group Id
          BG005
          value
          97
        title
        M0
      2. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          5
        3. group Id
          BG002
          value
          5
        4. group Id
          BG003
          value
          6
        5. group Id
          BG004
          value
          6
        6. group Id
          BG005
          value
          26
        title
        M1
      3. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          2
        title
        Missing
      4. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          3
        6. group Id
          BG005
          value
          5
        title
        Unobtainable
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    The 7th edition of TNM staging was used. Larger number of M (metastasis) would be worse outcomes Reference: The 7th lung cancer TNM classification and staging system: Review of the changes and implications - PMC
    param Type
    COUNT_OF_PARTICIPANTS
    title
    M-stage
    unit Of Measure
    Participants
  12. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          6
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          6
        title
        Positive
      2. measurements
        1. group Id
          BG000
          value
          20
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          46
        title
        Negative
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          78
        title
        Not applicable
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    Measurement of P16: p16ink4a was assessed via immunohistochemistry via a central laboratory and determined to have loss or retained.
    param Type
    COUNT_OF_PARTICIPANTS
    title
    P16
    unit Of Measure
    Participants
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      26
    2. group Id
      BG001
      value
      26
    3. group Id
      BG002
      value
      26
    4. group Id
      BG003
      value
      26
    5. group Id
      BG004
      value
      26
    6. group Id
      BG005
      value
      130
    units
    Participants
groups
  1. description
    Rucaparib in DNA damage sensitive relapsed mesothelioma
    id
    BG000
    title
    MiST-1
  2. description
    Abemaciclib in p16INK4A negative mesothelioma
    id
    BG001
    title
    MiST-2
  3. description
    Pembrolizumab and bemcentinib in relapsed mesothelioma
    id
    BG002
    title
    MiST-3
  4. description
    Atezolizumab and Bevacizumab in relapsed mesothelioma
    id
    BG003
    title
    MiST-4
  5. description
    Dostarlimab and Niraparib in Patients with Platinum Sensitive Relapsed Mesothelioma
    id
    BG004
    title
    MiST-5
  6. description
    Total of all reporting groups
    id
    BG005
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          lower Limit
          60.0
          upper Limit
          71.0
          value
          66.5
        2. group Id
          BG001
          lower Limit
          64.0
          upper Limit
          74.0
          value
          67.5
        3. group Id
          BG002
          lower Limit
          69.0
          upper Limit
          75.0
          value
          72.5
        4. group Id
          BG003
          lower Limit
          67.0
          upper Limit
          74.0
          value
          68.0
        5. group Id
          BG004
          lower Limit
          68.0
          upper Limit
          74.0
          value
          69.5
        6. group Id
          BG005
          lower Limit
          64.0
          upper Limit
          74.0
          value
          69.0
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    dispersion Type
    INTER_QUARTILE_RANGE
    param Type
    MEDIAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          3
        3. group Id
          BG002
          value
          3
        4. group Id
          BG003
          value
          8
        5. group Id
          BG004
          value
          5
        6. group Id
          BG005
          value
          23
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          22
        2. group Id
          BG001
          value
          23
        3. group Id
          BG002
          value
          23
        4. group Id
          BG003
          value
          18
        5. group Id
          BG004
          value
          21
        6. group Id
          BG005
          value
          107
        title
        Male
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG005
          value
          0
      denoms
      1. counts
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          0
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    population Description
    Race and Ethnicity were not collected from any participant.
    title
    Race and Ethnicity Not Collected
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          21
        2. group Id
          BG001
          value
          21
        3. group Id
          BG002
          value
          23
        4. group Id
          BG003
          value
          20
        5. group Id
          BG004
          value
          21
        6. group Id
          BG005
          value
          106
        title
        Epithelioid
      2. measurements
        1. group Id
          BG000
          value
          5
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          14
        title
        Biphasic
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          6
        title
        Sarcomatoid
      4. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          4
        title
        NOS
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Mesothelioma subtype
    unit Of Measure
    Participants
  5. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          4
        6. group Id
          BG005
          value
          11
        title
        Smoker
      2. measurements
        1. group Id
          BG000
          value
          15
        2. group Id
          BG001
          value
          14
        3. group Id
          BG002
          value
          12
        4. group Id
          BG003
          value
          13
        5. group Id
          BG004
          value
          12
        6. group Id
          BG005
          value
          66
        title
        Non-smoker
      3. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          13
        4. group Id
          BG003
          value
          11
        5. group Id
          BG004
          value
          10
        6. group Id
          BG005
          value
          53
        title
        Ex-smoker
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Smoking status
    unit Of Measure
    Participants
  6. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          15
        2. group Id
          BG001
          value
          20
        3. group Id
          BG002
          value
          20
        4. group Id
          BG003
          value
          16
        5. group Id
          BG004
          value
          18
        6. group Id
          BG005
          value
          89
        title
        Yes
      2. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          2
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          6
        title
        No
      3. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          8
        5. group Id
          BG004
          value
          8
        6. group Id
          BG005
          value
          35
        title
        Unknown
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    param Type
    COUNT_OF_PARTICIPANTS
    title
    History of asbestos
    unit Of Measure
    Participants
  7. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          4
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          20
        title
        Zero
      2. measurements
        1. group Id
          BG000
          value
          22
        2. group Id
          BG001
          value
          22
        3. group Id
          BG002
          value
          20
        4. group Id
          BG003
          value
          22
        5. group Id
          BG004
          value
          24
        6. group Id
          BG005
          value
          110
        title
        One
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    PS 0 would be expected to have better outcomes than PS 1 Grade=0: Fully active, able to carry on all pre-disease performance without restriction Grade=1: Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house work, office work Original Reference: Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982 Dec;5(6):649-655. PMID: 7165009.
    param Type
    COUNT_OF_PARTICIPANTS
    title
    ECOG status
    unit Of Measure
    Participants
  8. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          25
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          25
        4. group Id
          BG003
          value
          24
        5. group Id
          BG004
          value
          24
        6. group Id
          BG005
          value
          124
        title
        Thoracic
      2. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          4
        title
        Abdominal
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          1
        title
        Missing
      4. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          1
        title
        Pelvis
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    Primary tumour site is : "the original location where mesothelioma was diagnosed". There is no clear prognostic difference between Thorax/Abdomen/Pelvis as such and do not represent stages or grades.
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Primary Tumour site
    unit Of Measure
    Participants
  9. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          5
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          6
        6. group Id
          BG005
          value
          20
        title
        T1
      2. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          9
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          4
        6. group Id
          BG005
          value
          21
        title
        T2
      3. measurements
        1. group Id
          BG000
          value
          10
        2. group Id
          BG001
          value
          5
        3. group Id
          BG002
          value
          9
        4. group Id
          BG003
          value
          7
        5. group Id
          BG004
          value
          6
        6. group Id
          BG005
          value
          37
        title
        T3
      4. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          13
        5. group Id
          BG004
          value
          8
        6. group Id
          BG005
          value
          44
        title
        T4
      5. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          2
        title
        Missing
      6. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          3
        title
        TX
      7. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          3
        title
        Unobtainable
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    The 7th edition of TNM staging was used. Larger number of T (tumour) would be worse outcomes Reference: The 7th lung cancer TNM classification and staging system: Review of the changes and implications - PMC
    param Type
    COUNT_OF_PARTICIPANTS
    title
    T-stage
    unit Of Measure
    Participants
  10. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          16
        4. group Id
          BG003
          value
          11
        5. group Id
          BG004
          value
          13
        6. group Id
          BG005
          value
          59
        title
        N0
      2. measurements
        1. group Id
          BG000
          value
          6
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          6
        4. group Id
          BG003
          value
          6
        5. group Id
          BG004
          value
          7
        6. group Id
          BG005
          value
          33
        title
        N1
      3. measurements
        1. group Id
          BG000
          value
          7
        2. group Id
          BG001
          value
          8
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          8
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          27
        title
        N2
      4. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
        5. group Id
          BG004
          value
          2
        6. group Id
          BG005
          value
          6
        title
        N3
      5. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          2
        title
        Missing
      6. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          3
        title
        Unobtainable
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    The 7th edition of TNM staging was used. Larger number of N (nodes) would be worse outcomes Reference: The 7th lung cancer TNM classification and staging system: Review of the changes and implications - PMC
    param Type
    COUNT_OF_PARTICIPANTS
    title
    N-stage
    unit Of Measure
    Participants
  11. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          21
        2. group Id
          BG001
          value
          21
        3. group Id
          BG002
          value
          19
        4. group Id
          BG003
          value
          20
        5. group Id
          BG004
          value
          16
        6. group Id
          BG005
          value
          97
        title
        M0
      2. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          5
        3. group Id
          BG002
          value
          5
        4. group Id
          BG003
          value
          6
        5. group Id
          BG004
          value
          6
        6. group Id
          BG005
          value
          26
        title
        M1
      3. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        6. group Id
          BG005
          value
          2
        title
        Missing
      4. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          3
        6. group Id
          BG005
          value
          5
        title
        Unobtainable
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    The 7th edition of TNM staging was used. Larger number of M (metastasis) would be worse outcomes Reference: The 7th lung cancer TNM classification and staging system: Review of the changes and implications - PMC
    param Type
    COUNT_OF_PARTICIPANTS
    title
    M-stage
    unit Of Measure
    Participants
  12. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          6
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          6
        title
        Positive
      2. measurements
        1. group Id
          BG000
          value
          20
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          0
        6. group Id
          BG005
          value
          46
        title
        Negative
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          78
        title
        Not applicable
      denoms
      1. counts
        1. group Id
          BG000
          value
          26
        2. group Id
          BG001
          value
          26
        3. group Id
          BG002
          value
          26
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          26
        6. group Id
          BG005
          value
          130
        units
        Participants
    description
    Measurement of P16: p16ink4a was assessed via immunohistochemistry via a central laboratory and determined to have loss or retained.
    param Type
    COUNT_OF_PARTICIPANTS
    title
    P16
    unit Of Measure
    Participants

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Preserved source evidence · Independent clinical review pending · Not medical advice