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NCT03568461 · OUTCOME

Tisagenlecleucel Transgene Concentration Levels as Measured by Quantitative Polymerase Chain Reaction (qPCR) Method, by Clinical Response Per IRC Assessment

Efficacy and Safety of Tisagenlecleucel in Adult Patients With Refractory or Relapsed Follicular Lymphoma · Source last updated 2026-07-09

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
GEOMETRIC_MEAN
Unit
copies/ug DNA
Interval / dispersion
Geometric Coefficient of Variation
Time frame
Month 60 (peripheral blood), Month 6 (bone marrow)

What was measured

This is the summary of cellular kinetic concentrations for tisagenlecleucel (CTL019) transgene levels in peripheral blood and bone marrow following infusion.

Analysis population: Participants in the Cellular kinetic set (CKAS) with an available value for the outcome measure. The CKAS consisted of patients in the Efficacy analysis set who provided an evaluable cellular kinetic profile (at least 1 cellular kinetic parameter).

Groups in this outcome

CTL019

All participants who were enrolled in the study

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
CTL01922

Reported measurements

Peripheral blood

Analysis denominator · Participants

GroupSource count
CTL01922
Values in copies/ug DNA · Interval/dispersion: Geometric Coefficient of Variation
GroupValueSpreadLowerUpperComment
CTL019202126Not reportedNot reportedNot reported
Bone marrow

Analysis denominator · Participants

GroupSource count
CTL0192
Values in copies/ug DNA · Interval/dispersion: Geometric Coefficient of Variation
GroupValueSpreadLowerUpperComment
CTL0193173.17Not reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        spread
        126
        value
        202
    denoms
    1. counts
      1. group Id
        OG000
        value
        22
      units
      Participants
    title
    Peripheral blood
  2. categories
    1. measurements
      1. group Id
        OG000
        spread
        3.17
        value
        317
    denoms
    1. counts
      1. group Id
        OG000
        value
        2
      units
      Participants
    title
    Bone marrow
denoms
  1. counts
    1. group Id
      OG000
      value
      22
    units
    Participants
description
This is the summary of cellular kinetic concentrations for tisagenlecleucel (CTL019) transgene levels in peripheral blood and bone marrow following infusion.
dispersion Type
Geometric Coefficient of Variation
groups
  1. description
    All participants who were enrolled in the study
    id
    OG000
    title
    CTL019
param Type
GEOMETRIC_MEAN
population Description
Participants in the Cellular kinetic set (CKAS) with an available value for the outcome measure. The CKAS consisted of patients in the Efficacy analysis set who provided an evaluable cellular kinetic profile (at least 1 cellular kinetic parameter).
reporting Status
POSTED
time Frame
Month 60 (peripheral blood), Month 6 (bone marrow)
title
Tisagenlecleucel Transgene Concentration Levels as Measured by Quantitative Polymerase Chain Reaction (qPCR) Method, by Clinical Response Per IRC Assessment
type
SECONDARY
unit Of Measure
copies/ug DNA

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice