NCT03465722 · BASELINE

Baseline characteristics

(VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST · Source last updated 2022-10-06

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants

groups

description
300 mg PO QD avapritinib: Avapritinib tablets for oral administration. Avapritinib will be dosed at 300 mg once daily, continuously.
id
BG000
title
Avapritinib
description
160 mg PO QD regorafenib: Regorafenib tablets for oral administration. Regorafenib will be dosed at 160 mg once daily for 3 weeks out of every 4 weeks (ie. 3 weeks on/1 week off).
id
BG001
title
Regorafinib
description
Total of all reporting groups
id
BG002
title
Total

measures

classes
categories
measurements
group Id
BG000
spread
10.96
value
61.1
group Id
BG001
spread
10.74
value
61.0
group Id
BG002
spread
10.84
value
61.1
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
title
Age, Continuous
unit Of Measure
years
classes
categories
measurements
group Id
BG000
value
78
group Id
BG001
value
80
group Id
BG002
value
158
title
Female
measurements
group Id
BG000
value
162
group Id
BG001
value
156
group Id
BG002
value
318
title
Male
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
param Type
COUNT_OF_PARTICIPANTS
title
Sex: Female, Male
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
title
American Indian or Alaska Native
measurements
group Id
BG000
value
64
group Id
BG001
value
64
group Id
BG002
value
128
title
Asian
measurements
group Id
BG000
value
1
group Id
BG001
value
1
group Id
BG002
value
2
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
9
group Id
BG001
value
5
group Id
BG002
value
14
title
Black or African American
measurements
group Id
BG000
value
139
group Id
BG001
value
143
group Id
BG002
value
282
title
White
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
title
More than one race
measurements
group Id
BG000
value
27
group Id
BG001
value
23
group Id
BG002
value
50
title
Unknown or Not Reported
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
param Type
COUNT_OF_PARTICIPANTS
title
Race (NIH/OMB)
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
2
group Id
BG002
value
4
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Singapore
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
1
group Id
BG002
value
3
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Hungary
categories
measurements
group Id
BG000
value
71
group Id
BG001
value
62
group Id
BG002
value
133
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
United States
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
1
group Id
BG002
value
4
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Czechia
categories
measurements
group Id
BG000
value
12
group Id
BG001
value
12
group Id
BG002
value
24
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
United Kingdom
categories
measurements
group Id
BG000
value
14
group Id
BG001
value
11
group Id
BG002
value
25
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Spain
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
6
group Id
BG002
value
8
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Canada
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
1
group Id
BG002
value
1
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Austria
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
6
group Id
BG002
value
8
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Netherlands
categories
measurements
group Id
BG000
value
23
group Id
BG001
value
20
group Id
BG002
value
43
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
South Korea
categories
measurements
group Id
BG000
value
6
group Id
BG001
value
7
group Id
BG002
value
13
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Sweden
categories
measurements
group Id
BG000
value
1
group Id
BG001
value
1
group Id
BG002
value
2
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Belgium
param Type
NUMBER
title
Region of Enrollment
unit Of Measure
participants
classes
categories
measurements
group Id
BG000
spread
5.563
value
25.50
group Id
BG001
spread
5.163
value
24.69
group Id
BG002
spread
5.378
value
25.10
denoms
counts
group Id
BG000
value
230
group Id
BG001
value
225
group Id
BG002
value
455
units
Participants
description
Both height and weight measurements are needed for body mass index calculation. Some patients had missing height and/or weight measurements. Only patients with both a height and a weight measurement are included in the body mass index calculation
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
population Description
Both height and weight measurements are needed for body mass index calculation. Some patients had missing height and/or weight measurements. Only patients with both a height and a weight measurement are included in the body mass index calculation
title
Body Mass Index (BMI)
unit Of Measure
kilogram per meter square

Complete source fields

denoms

counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants

groups

description
300 mg PO QD avapritinib: Avapritinib tablets for oral administration. Avapritinib will be dosed at 300 mg once daily, continuously.
id
BG000
title
Avapritinib
description
160 mg PO QD regorafenib: Regorafenib tablets for oral administration. Regorafenib will be dosed at 160 mg once daily for 3 weeks out of every 4 weeks (ie. 3 weeks on/1 week off).
id
BG001
title
Regorafinib
description
Total of all reporting groups
id
BG002
title
Total

measures

classes
categories
measurements
group Id
BG000
spread
10.96
value
61.1
group Id
BG001
spread
10.74
value
61.0
group Id
BG002
spread
10.84
value
61.1
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
title
Age, Continuous
unit Of Measure
years
classes
categories
measurements
group Id
BG000
value
78
group Id
BG001
value
80
group Id
BG002
value
158
title
Female
measurements
group Id
BG000
value
162
group Id
BG001
value
156
group Id
BG002
value
318
title
Male
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
param Type
COUNT_OF_PARTICIPANTS
title
Sex: Female, Male
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
title
American Indian or Alaska Native
measurements
group Id
BG000
value
64
group Id
BG001
value
64
group Id
BG002
value
128
title
Asian
measurements
group Id
BG000
value
1
group Id
BG001
value
1
group Id
BG002
value
2
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
9
group Id
BG001
value
5
group Id
BG002
value
14
title
Black or African American
measurements
group Id
BG000
value
139
group Id
BG001
value
143
group Id
BG002
value
282
title
White
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
title
More than one race
measurements
group Id
BG000
value
27
group Id
BG001
value
23
group Id
BG002
value
50
title
Unknown or Not Reported
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
param Type
COUNT_OF_PARTICIPANTS
title
Race (NIH/OMB)
unit Of Measure
Participants
classes
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
2
group Id
BG002
value
4
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Singapore
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
1
group Id
BG002
value
3
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Hungary
categories
measurements
group Id
BG000
value
71
group Id
BG001
value
62
group Id
BG002
value
133
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
United States
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
1
group Id
BG002
value
4
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Czechia
categories
measurements
group Id
BG000
value
12
group Id
BG001
value
12
group Id
BG002
value
24
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
United Kingdom
categories
measurements
group Id
BG000
value
14
group Id
BG001
value
11
group Id
BG002
value
25
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Spain
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
6
group Id
BG002
value
8
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Canada
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
1
group Id
BG002
value
1
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Austria
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
6
group Id
BG002
value
8
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Netherlands
categories
measurements
group Id
BG000
value
23
group Id
BG001
value
20
group Id
BG002
value
43
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
South Korea
categories
measurements
group Id
BG000
value
6
group Id
BG001
value
7
group Id
BG002
value
13
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Sweden
categories
measurements
group Id
BG000
value
1
group Id
BG001
value
1
group Id
BG002
value
2
denoms
counts
group Id
BG000
value
240
group Id
BG001
value
236
group Id
BG002
value
476
units
Participants
title
Belgium
param Type
NUMBER
title
Region of Enrollment
unit Of Measure
participants
classes
categories
measurements
group Id
BG000
spread
5.563
value
25.50
group Id
BG001
spread
5.163
value
24.69
group Id
BG002
spread
5.378
value
25.10
denoms
counts
group Id
BG000
value
230
group Id
BG001
value
225
group Id
BG002
value
455
units
Participants
description
Both height and weight measurements are needed for body mass index calculation. Some patients had missing height and/or weight measurements. Only patients with both a height and a weight measurement are included in the body mass index calculation
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
population Description
Both height and weight measurements are needed for body mass index calculation. Some patients had missing height and/or weight measurements. Only patients with both a height and a weight measurement are included in the body mass index calculation
title
Body Mass Index (BMI)
unit Of Measure
kilogram per meter square

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice