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NCT03375320 · BASELINE

Baseline characteristics

Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors · Source last updated 2026-08-04

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      134
    2. group Id
      BG001
      value
      69
    3. group Id
      BG002
      value
      64
    4. group Id
      BG003
      value
      31
    5. group Id
      BG004
      value
      298
    units
    Participants
groups
  1. description
    Patients receive cabozantinib S-malate PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT, MRI, and/or x-ray imaging during screening and on study.\> \> Cabozantinib S-malate: Given PO\> \> Computed Tomography: Undergo CT\> \> Magnetic Resonance Imaging: Undergo MRI\> \> Quality-of-Life Assessment: Ancillary studies\> \> X-Ray Imaging: Undergo x-ray
    id
    BG000
    title
    Arm Ia (Cabozantinib S-malate, Extra-pancreatic NET Cohort [epNET])
  2. description
    Patients receive placebo PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT, MRI, and/or x-ray imaging during screening and on study. Patients may crossover to receive cabozantinib S-malate at the time of disease progression.\> \> Computed Tomography: Undergo CT\> \> Magnetic Resonance Imaging: Undergo MRI\> \> Placebo Administration: Given PO\> \> Quality-of-Life Assessment: Ancillary studies\> \> X-Ray Imaging: Undergo x-ray
    id
    BG001
    title
    Arm IIa (Placebo, Extra-pancreatic NET Cohort [epNET])
  3. description
    Patients receive cabozantinib S-malate PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT, MRI, and/or x-ray imaging during screening and on study.\> \> Cabozantinib S-malate: Given PO\> \> Computed Tomography: Undergo CT\> \> Magnetic Resonance Imaging: Undergo MRI\> \> Quality-of-Life Assessment: Ancillary studies\> \> X-Ray Imaging: Undergo x-ray
    id
    BG002
    title
    Arm Ib (Cabozantinib S-malate, Pancreatic NET Cohort [pNET])
  4. description
    Patients receive placebo PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT, MRI, and/or x-ray imaging during screening and on study. Patients may crossover to receive cabozantinib S-malate at the time of disease progression.\> \> Computed Tomography: Undergo CT\> \> Magnetic Resonance Imaging: Undergo MRI\> \> Placebo Administration: Given PO\> \> Quality-of-Life Assessment: Ancillary studies\> \> X-Ray Imaging: Undergo x-ray
    id
    BG003
    title
    Arm IIb (Placebo, Pancreatic NET Cohort [pNET])
  5. description
    Total of all reporting groups
    id
    BG004
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          lower Limit
          28
          upper Limit
          86
          value
          66
        2. group Id
          BG001
          lower Limit
          30
          upper Limit
          82
          value
          66
        3. group Id
          BG002
          lower Limit
          29
          upper Limit
          79
          value
          59.5
        4. group Id
          BG003
          lower Limit
          39
          upper Limit
          79
          value
          64
        5. group Id
          BG004
          lower Limit
          28
          upper Limit
          86
          value
          66
    dispersion Type
    FULL_RANGE
    param Type
    MEDIAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          74
        2. group Id
          BG001
          value
          31
        3. group Id
          BG002
          value
          27
        4. group Id
          BG003
          value
          13
        5. group Id
          BG004
          value
          145
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          60
        2. group Id
          BG001
          value
          38
        3. group Id
          BG002
          value
          37
        4. group Id
          BG003
          value
          18
        5. group Id
          BG004
          value
          153
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          8
        2. group Id
          BG001
          value
          9
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          21
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          125
        2. group Id
          BG001
          value
          56
        3. group Id
          BG002
          value
          61
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          268
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          9
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        title
        American Indian or Alaska Native
      2. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          8
        title
        Asian
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        title
        Native Hawaiian or Other Pacific Islander
      4. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          7
        3. group Id
          BG002
          value
          3
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          22
        title
        Black or African American
      5. measurements
        1. group Id
          BG000
          value
          115
        2. group Id
          BG001
          value
          55
        3. group Id
          BG002
          value
          54
        4. group Id
          BG003
          value
          25
        5. group Id
          BG004
          value
          249
        title
        White
      6. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        title
        More than one race
      7. measurements
        1. group Id
          BG000
          value
          7
        2. group Id
          BG001
          value
          6
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          16
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race (NIH/OMB)
    unit Of Measure
    Participants
  5. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          134
        2. group Id
          BG001
          value
          69
        3. group Id
          BG002
          value
          64
        4. group Id
          BG003
          value
          31
        5. group Id
          BG004
          value
          298
      title
      United States
    param Type
    NUMBER
    title
    Region of Enrollment
    unit Of Measure
    participants
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      134
    2. group Id
      BG001
      value
      69
    3. group Id
      BG002
      value
      64
    4. group Id
      BG003
      value
      31
    5. group Id
      BG004
      value
      298
    units
    Participants
groups
  1. description
    Patients receive cabozantinib S-malate PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT, MRI, and/or x-ray imaging during screening and on study.\> \> Cabozantinib S-malate: Given PO\> \> Computed Tomography: Undergo CT\> \> Magnetic Resonance Imaging: Undergo MRI\> \> Quality-of-Life Assessment: Ancillary studies\> \> X-Ray Imaging: Undergo x-ray
    id
    BG000
    title
    Arm Ia (Cabozantinib S-malate, Extra-pancreatic NET Cohort [epNET])
  2. description
    Patients receive placebo PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT, MRI, and/or x-ray imaging during screening and on study. Patients may crossover to receive cabozantinib S-malate at the time of disease progression.\> \> Computed Tomography: Undergo CT\> \> Magnetic Resonance Imaging: Undergo MRI\> \> Placebo Administration: Given PO\> \> Quality-of-Life Assessment: Ancillary studies\> \> X-Ray Imaging: Undergo x-ray
    id
    BG001
    title
    Arm IIa (Placebo, Extra-pancreatic NET Cohort [epNET])
  3. description
    Patients receive cabozantinib S-malate PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT, MRI, and/or x-ray imaging during screening and on study.\> \> Cabozantinib S-malate: Given PO\> \> Computed Tomography: Undergo CT\> \> Magnetic Resonance Imaging: Undergo MRI\> \> Quality-of-Life Assessment: Ancillary studies\> \> X-Ray Imaging: Undergo x-ray
    id
    BG002
    title
    Arm Ib (Cabozantinib S-malate, Pancreatic NET Cohort [pNET])
  4. description
    Patients receive placebo PO QD on days 1-28 of each cycle. Cycles repeat every 28 days in the absence of disease progression or unacceptable toxicity. Patients also undergo CT, MRI, and/or x-ray imaging during screening and on study. Patients may crossover to receive cabozantinib S-malate at the time of disease progression.\> \> Computed Tomography: Undergo CT\> \> Magnetic Resonance Imaging: Undergo MRI\> \> Placebo Administration: Given PO\> \> Quality-of-Life Assessment: Ancillary studies\> \> X-Ray Imaging: Undergo x-ray
    id
    BG003
    title
    Arm IIb (Placebo, Pancreatic NET Cohort [pNET])
  5. description
    Total of all reporting groups
    id
    BG004
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          lower Limit
          28
          upper Limit
          86
          value
          66
        2. group Id
          BG001
          lower Limit
          30
          upper Limit
          82
          value
          66
        3. group Id
          BG002
          lower Limit
          29
          upper Limit
          79
          value
          59.5
        4. group Id
          BG003
          lower Limit
          39
          upper Limit
          79
          value
          64
        5. group Id
          BG004
          lower Limit
          28
          upper Limit
          86
          value
          66
    dispersion Type
    FULL_RANGE
    param Type
    MEDIAN
    title
    Age, Continuous
    unit Of Measure
    years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          74
        2. group Id
          BG001
          value
          31
        3. group Id
          BG002
          value
          27
        4. group Id
          BG003
          value
          13
        5. group Id
          BG004
          value
          145
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          60
        2. group Id
          BG001
          value
          38
        3. group Id
          BG002
          value
          37
        4. group Id
          BG003
          value
          18
        5. group Id
          BG004
          value
          153
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          8
        2. group Id
          BG001
          value
          9
        3. group Id
          BG002
          value
          2
        4. group Id
          BG003
          value
          2
        5. group Id
          BG004
          value
          21
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          125
        2. group Id
          BG001
          value
          56
        3. group Id
          BG002
          value
          61
        4. group Id
          BG003
          value
          26
        5. group Id
          BG004
          value
          268
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          9
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        title
        American Indian or Alaska Native
      2. measurements
        1. group Id
          BG000
          value
          3
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          8
        title
        Asian
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        title
        Native Hawaiian or Other Pacific Islander
      4. measurements
        1. group Id
          BG000
          value
          9
        2. group Id
          BG001
          value
          7
        3. group Id
          BG002
          value
          3
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          22
        title
        Black or African American
      5. measurements
        1. group Id
          BG000
          value
          115
        2. group Id
          BG001
          value
          55
        3. group Id
          BG002
          value
          54
        4. group Id
          BG003
          value
          25
        5. group Id
          BG004
          value
          249
        title
        White
      6. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        4. group Id
          BG003
          value
          0
        5. group Id
          BG004
          value
          1
        title
        More than one race
      7. measurements
        1. group Id
          BG000
          value
          7
        2. group Id
          BG001
          value
          6
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          3
        5. group Id
          BG004
          value
          16
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race (NIH/OMB)
    unit Of Measure
    Participants
  5. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          134
        2. group Id
          BG001
          value
          69
        3. group Id
          BG002
          value
          64
        4. group Id
          BG003
          value
          31
        5. group Id
          BG004
          value
          298
      title
      United States
    param Type
    NUMBER
    title
    Region of Enrollment
    unit Of Measure
    participants

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice