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NCT03287804 · FLOW

Participant flow

APRIL CAR T Cells (AUTO2) Targeting BCMA and TACI for the Treatment of Multiple Myeloma · Source last updated 2020-10-23

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups
  1. description
    Relapsed or refractory myeloma patients.
    id
    FG000
    title
    AUTO2
periods
  1. drop Withdraws
    1. reasons
      1. group Id
        FG000
        num Subjects
        1
      type
      Death
    2. reasons
      1. group Id
        FG000
        num Subjects
        2
      type
      Physician Decision
    3. reasons
      1. group Id
        FG000
        num Subjects
        8
      type
      Progressive disease
    milestones
    1. achievements
      1. group Id
        FG000
        num Subjects
        12
      type
      STARTED
    2. achievements
      1. group Id
        FG000
        num Subjects
        12
      type
      Leukaperesed
    3. achievements
      1. group Id
        FG000
        num Subjects
        11
      type
      Started Pre-conditioning Therapy
    4. achievements
      1. group Id
        FG000
        num Subjects
        11
      type
      Received Study Treatment
    5. achievements
      1. group Id
        FG000
        num Subjects
        1
      type
      COMPLETED
    6. achievements
      1. group Id
        FG000
        num Subjects
        11
      type
      NOT COMPLETED
    title
    Overall Study
pre Assignment Details
Screening procedures were performed up to 12 weeks before study treatment administered
recruitment Details
Following preconditioning with chemotherapy (cyclophosphamide and fludarabine) patients were treated with doses from 15 x 10⁶ to 350 x 10⁶ APRIL CAR T Cells.
Complete source fields
groups
  1. description
    Relapsed or refractory myeloma patients.
    id
    FG000
    title
    AUTO2
periods
  1. drop Withdraws
    1. reasons
      1. group Id
        FG000
        num Subjects
        1
      type
      Death
    2. reasons
      1. group Id
        FG000
        num Subjects
        2
      type
      Physician Decision
    3. reasons
      1. group Id
        FG000
        num Subjects
        8
      type
      Progressive disease
    milestones
    1. achievements
      1. group Id
        FG000
        num Subjects
        12
      type
      STARTED
    2. achievements
      1. group Id
        FG000
        num Subjects
        12
      type
      Leukaperesed
    3. achievements
      1. group Id
        FG000
        num Subjects
        11
      type
      Started Pre-conditioning Therapy
    4. achievements
      1. group Id
        FG000
        num Subjects
        11
      type
      Received Study Treatment
    5. achievements
      1. group Id
        FG000
        num Subjects
        1
      type
      COMPLETED
    6. achievements
      1. group Id
        FG000
        num Subjects
        11
      type
      NOT COMPLETED
    title
    Overall Study
pre Assignment Details
Screening procedures were performed up to 12 weeks before study treatment administered
recruitment Details
Following preconditioning with chemotherapy (cyclophosphamide and fludarabine) patients were treated with doses from 15 x 10⁶ to 350 x 10⁶ APRIL CAR T Cells.

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Preserved source evidence · Not medical advice