Baseline characteristics

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma · Source last updated 2026-08-04

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      28

   units

   Participants

groups

1. description

   NEOADJUVANT: Patients receive atezolizumab IV over 30-60 minutes, pemetrexed disodium IV over 10 minutes, and cisplatin IV over 2 hours on day 1. Cycles repeats every 21 days for 4 cycles in the absence of disease progression or unexpected toxicity. SURGERY: Within 21-90 days after completion of neoadjuvant therapy, patients undergo extrapleural pneumonectomy (EPP) or pleurectomy/decortication (PD). Patients who undergo EPP will then undergo radiation therapy. MAINTENANCE: Within 90 days after completion of either PD or radiation (post-EPP), patients receive atezolizumab IV over 60 minutes on day 1. Treatment repeats every 21 days for up to 1 year in the absence of disease progression or unexpected toxicity.

   id

   BG000

   title

   Treatment (Chemotherapy, Surgery +/- RT, Maintenance)

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            lower Limit

            31.5

            upper Limit

            77.3

            value

            68.1

   dispersion Type

   FULL_RANGE

   param Type

   MEDIAN

   title

   Age, Continuous

   unit Of Measure

   years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            8

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            20

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            27

         title

         No

      2. measurements

         1. group Id

            BG000

            value

            1

         title

         Unknown

      title

      Hispanic

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Race/Ethnicity, Customized

   unit Of Measure

   Participants

4. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            24

         title

         White

      2. measurements

         1. group Id

            BG000

            value

            3

         title

         Asian

      3. measurements

         1. group Id

            BG000

            value

            1

         title

         Unknown

      title

      Race

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Race/Ethnicity, Customized

   unit Of Measure

   Participants

5. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            4

         title

         Extrapleural Pneumonectomy (EPP)

      2. measurements

         1. group Id

            BG000

            value

            24

         title

         Pleurectomy/Decortication (PD)

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Surgery

   unit Of Measure

   Participants

6. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            15

         title

         0

      2. measurements

         1. group Id

            BG000

            value

            13

         title

         1

   description

   Performance Status uses the Zubrod Scale as follows: 0 - Fully active, able to carry on all pre-disease performance w/o restriction 1 - Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light housework, office work

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Performance Status

   unit Of Measure

   Participants

7. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            23

         title

         <6%

      2. measurements

         1. group Id

            BG000

            value

            4

         title

         5-<10%

      3. measurements

         1. group Id

            BG000

            value

            1

         title

         Pending

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Weight Loss Past 6 Months

   unit Of Measure

   Participants

8. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            22

         title

         Measurable

      2. measurements

         1. group Id

            BG000

            value

            6

         title

         Not Assessable

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Baseline Disease Status mRECIST

   unit Of Measure

   Participants

9. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            14

         title

         Measurable

      2. measurements

         1. group Id

            BG000

            value

            14

         title

         Non-Measurable

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Baseline Disease Status RECIST

   unit Of Measure

   Participants

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Preserved source evidence · Not medical advice