Baseline characteristics

A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM) · Source last updated 2024-10-26

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      99

   2. group Id

      BG001

      value

      102

   3. group Id

      BG002

      value

      201

   units

   Participants

groups

1. description

   Participants diagnosed with WM with mutated MYD88 gene received 420 mg ibrutinib once daily orally until progressive disease, unacceptable toxicity, death, withdrawal of consent, or study termination by sponsor

   id

   BG000

   title

   Arm A: Ibrutinib

2. description

   Participants diagnosed with WM with mutated MYD88 gene received 160 mg zanubrutinib twice daily orally until progressive disease, unacceptable toxicity, death, withdrawal of consent, or study termination by sponsor

   id

   BG001

   title

   Arm B: Zanubrutinib

3. description

   Total of all reporting groups

   id

   BG002

   title

   Total

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            spread

            8.58

            value

            69.9

         2. group Id

            BG001

            spread

            10.26

            value

            69.2

         3. group Id

            BG002

            spread

            9.46

            value

            69.5

   dispersion Type

   STANDARD_DEVIATION

   param Type

   MEAN

   title

   Age, Continuous

   unit Of Measure

   years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            34

         2. group Id

            BG001

            value

            33

         3. group Id

            BG002

            value

            67

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            65

         2. group Id

            BG001

            value

            69

         3. group Id

            BG002

            value

            134

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            4

         2. group Id

            BG001

            value

            4

         3. group Id

            BG002

            value

            8

         title

         Hispanic or Latino

      2. measurements

         1. group Id

            BG000

            value

            91

         2. group Id

            BG001

            value

            82

         3. group Id

            BG002

            value

            173

         title

         Not Hispanic or Latino

      3. measurements

         1. group Id

            BG000

            value

            4

         2. group Id

            BG001

            value

            16

         3. group Id

            BG002

            value

            20

         title

         Unknown or Not Reported

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Ethnicity (NIH/OMB)

   unit Of Measure

   Participants

4. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            0

         title

         American Indian or Alaska Native

      2. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            4

         3. group Id

            BG002

            value

            4

         title

         Asian

      3. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            0

         title

         Native Hawaiian or Other Pacific Islander

      4. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            0

         title

         Black or African American

      5. measurements

         1. group Id

            BG000

            value

            94

         2. group Id

            BG001

            value

            88

         3. group Id

            BG002

            value

            182

         title

         White

      6. measurements

         1. group Id

            BG000

            value

            0

         2. group Id

            BG001

            value

            0

         3. group Id

            BG002

            value

            0

         title

         More than one race

      7. measurements

         1. group Id

            BG000

            value

            5

         2. group Id

            BG001

            value

            10

         3. group Id

            BG002

            value

            15

         title

         Unknown or Not Reported

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Race (NIH/OMB)

   unit Of Measure

   Participants

population Description

Intent to Treat (ITT) Analysis Set: Includes all randomized participants assigned to an arm.

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Preserved source evidence · Not medical advice