Skip to content
Triangle logo TriangleGet started
← Full study record

NCT02998528 · BASELINE

Baseline characteristics

A Neoadjuvant Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Versus Chemotherapy Alone in Early Stage Non-Small Cell Lung Cancer (NSCLC) · Source last updated 2026-01-06

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      113
    2. group Id
      BG001
      value
      213
    3. group Id
      BG002
      value
      179
    4. group Id
      BG003
      value
      505
    units
    Participants
groups
  1. description
    Participants received nivolumab 3 mg/kg IV over 30 minutes every 2 weeks for up to 3 doses (ie, 6 weeks of treatment; each cycle is 14 days). In Cycle 1 Day 1 only, nivolumab will be followed by a single dose of ipilimumab 1 mg/kg IV over 30 minutes. Following definitive surgery, participants could receive up to 4 cycles of adjuvant chemotherapy and/or radiation at the discretion of the investigator.
    id
    BG000
    title
    Arm A: Nivo 3 mg/kg + Ipi 1 mg/kg
  2. description
    Participants receive investigator-choice of platinum doublet chemotherapy regimens in 3-week cycles up to a maximum of 3 cycles of IV chemotherapy (ie, 9 weeks of treatment; each cycle is 21 days). Following definitive surgery, participants could receive up to 4 cycles of adjuvant chemotherapy and/or radiation at the discretion of the investigator.
    id
    BG001
    title
    Arm B: Platinum Doublet Chemo
  3. description
    Participants receive nivolumab 360 mg IV + platinum doublet chemotherapy in 3-week cycles up to a maximum of 3 cycles of IV chemotherapy (ie, 9 weeks of treatment; each cycle is 21 days). Following definitive surgery, participants could receive up to 4 cycles of adjuvant chemotherapy and/or radiation at the discretion of the investigator.
    id
    BG002
    title
    Arm C: Nivo 360 mg + Platinum Doublet Chemo
  4. description
    Total of all reporting groups
    id
    BG003
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          62
        2. group Id
          BG001
          value
          99
        3. group Id
          BG002
          value
          93
        4. group Id
          BG003
          value
          254
      title
      < 65
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          40
        2. group Id
          BG001
          value
          96
        3. group Id
          BG002
          value
          75
        4. group Id
          BG003
          value
          211
      title
      >= 65 AND < 75
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          11
        2. group Id
          BG001
          value
          17
        3. group Id
          BG002
          value
          11
        4. group Id
          BG003
          value
          39
      title
      >= 75 AND < 85
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
      title
      >= 85
    param Type
    NUMBER
    title
    Age, Customized
    unit Of Measure
    Participants
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          40
        2. group Id
          BG001
          value
          65
        3. group Id
          BG002
          value
          51
        4. group Id
          BG003
          value
          156
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          73
        2. group Id
          BG001
          value
          148
        3. group Id
          BG002
          value
          128
        4. group Id
          BG003
          value
          349
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          5
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          7
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          53
        2. group Id
          BG001
          value
          105
        3. group Id
          BG002
          value
          100
        4. group Id
          BG003
          value
          258
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          58
        2. group Id
          BG001
          value
          103
        3. group Id
          BG002
          value
          79
        4. group Id
          BG003
          value
          240
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        title
        American Indian or Alaska Native
      2. measurements
        1. group Id
          BG000
          value
          41
        2. group Id
          BG001
          value
          96
        3. group Id
          BG002
          value
          86
        4. group Id
          BG003
          value
          223
        title
        Asian
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        title
        Native Hawaiian or Other Pacific Islander
      4. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          5
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          13
        title
        Black or African American
      5. measurements
        1. group Id
          BG000
          value
          64
        2. group Id
          BG001
          value
          108
        3. group Id
          BG002
          value
          89
        4. group Id
          BG003
          value
          261
        title
        White
      6. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        title
        More than one race
      7. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          8
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race (NIH/OMB)
    unit Of Measure
    Participants
population Description
All randomized participants
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      113
    2. group Id
      BG001
      value
      213
    3. group Id
      BG002
      value
      179
    4. group Id
      BG003
      value
      505
    units
    Participants
groups
  1. description
    Participants received nivolumab 3 mg/kg IV over 30 minutes every 2 weeks for up to 3 doses (ie, 6 weeks of treatment; each cycle is 14 days). In Cycle 1 Day 1 only, nivolumab will be followed by a single dose of ipilimumab 1 mg/kg IV over 30 minutes. Following definitive surgery, participants could receive up to 4 cycles of adjuvant chemotherapy and/or radiation at the discretion of the investigator.
    id
    BG000
    title
    Arm A: Nivo 3 mg/kg + Ipi 1 mg/kg
  2. description
    Participants receive investigator-choice of platinum doublet chemotherapy regimens in 3-week cycles up to a maximum of 3 cycles of IV chemotherapy (ie, 9 weeks of treatment; each cycle is 21 days). Following definitive surgery, participants could receive up to 4 cycles of adjuvant chemotherapy and/or radiation at the discretion of the investigator.
    id
    BG001
    title
    Arm B: Platinum Doublet Chemo
  3. description
    Participants receive nivolumab 360 mg IV + platinum doublet chemotherapy in 3-week cycles up to a maximum of 3 cycles of IV chemotherapy (ie, 9 weeks of treatment; each cycle is 21 days). Following definitive surgery, participants could receive up to 4 cycles of adjuvant chemotherapy and/or radiation at the discretion of the investigator.
    id
    BG002
    title
    Arm C: Nivo 360 mg + Platinum Doublet Chemo
  4. description
    Total of all reporting groups
    id
    BG003
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          62
        2. group Id
          BG001
          value
          99
        3. group Id
          BG002
          value
          93
        4. group Id
          BG003
          value
          254
      title
      < 65
    2. categories
      1. measurements
        1. group Id
          BG000
          value
          40
        2. group Id
          BG001
          value
          96
        3. group Id
          BG002
          value
          75
        4. group Id
          BG003
          value
          211
      title
      >= 65 AND < 75
    3. categories
      1. measurements
        1. group Id
          BG000
          value
          11
        2. group Id
          BG001
          value
          17
        3. group Id
          BG002
          value
          11
        4. group Id
          BG003
          value
          39
      title
      >= 75 AND < 85
    4. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          1
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          1
      title
      >= 85
    param Type
    NUMBER
    title
    Age, Customized
    unit Of Measure
    Participants
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          40
        2. group Id
          BG001
          value
          65
        3. group Id
          BG002
          value
          51
        4. group Id
          BG003
          value
          156
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          73
        2. group Id
          BG001
          value
          148
        3. group Id
          BG002
          value
          128
        4. group Id
          BG003
          value
          349
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          2
        2. group Id
          BG001
          value
          5
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          7
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          53
        2. group Id
          BG001
          value
          105
        3. group Id
          BG002
          value
          100
        4. group Id
          BG003
          value
          258
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          58
        2. group Id
          BG001
          value
          103
        3. group Id
          BG002
          value
          79
        4. group Id
          BG003
          value
          240
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        title
        American Indian or Alaska Native
      2. measurements
        1. group Id
          BG000
          value
          41
        2. group Id
          BG001
          value
          96
        3. group Id
          BG002
          value
          86
        4. group Id
          BG003
          value
          223
        title
        Asian
      3. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        title
        Native Hawaiian or Other Pacific Islander
      4. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          5
        3. group Id
          BG002
          value
          4
        4. group Id
          BG003
          value
          13
        title
        Black or African American
      5. measurements
        1. group Id
          BG000
          value
          64
        2. group Id
          BG001
          value
          108
        3. group Id
          BG002
          value
          89
        4. group Id
          BG003
          value
          261
        title
        White
      6. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          0
        title
        More than one race
      7. measurements
        1. group Id
          BG000
          value
          4
        2. group Id
          BG001
          value
          4
        3. group Id
          BG002
          value
          0
        4. group Id
          BG003
          value
          8
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Race (NIH/OMB)
    unit Of Measure
    Participants
population Description
All randomized participants

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice