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NCT02952534 · FLOW

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A Study of Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer and Homologous Recombination Gene Deficiency · Source last updated 2023-06-09

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups
  1. description
    Patients with a deleterious BRCA (breast cancer susceptibility gene) mutation detected in their tumor.
    id
    FG000
    title
    BRCA Mutation
  2. description
    Patients with a deleterious ATM (ataxia telangiectasia mutated serine/threonine kinase) mutation detected in their tumor.
    id
    FG001
    title
    ATM Mutation
  3. description
    Patients with a deleterious CDK12 (Cyclin-dependent kinase 12) mutation detected in their tumor.
    id
    FG002
    title
    CDK12 Mutation
  4. description
    Patients with a deleterious CHEK2 (Checkpoint Kinase 2) mutation detected in their tumor.
    id
    FG003
    title
    CHEK2 Mutation
  5. description
    Patients with other deleterious HRR (homologous recombination repair) gene mutation detected in their tumor.
    id
    FG004
    title
    Other Gene Mutation
periods
  1. milestones
    1. achievements
      1. group Id
        FG000
        num Subjects
        172
      2. group Id
        FG001
        num Subjects
        59
      3. group Id
        FG002
        num Subjects
        14
      4. group Id
        FG003
        num Subjects
        7
      5. group Id
        FG004
        num Subjects
        25
      type
      STARTED
    2. achievements
      1. group Id
        FG000
        num Subjects
        172
      2. group Id
        FG001
        num Subjects
        59
      3. group Id
        FG002
        num Subjects
        14
      4. group Id
        FG003
        num Subjects
        7
      5. group Id
        FG004
        num Subjects
        25
      type
      COMPLETED
    3. achievements
      1. group Id
        FG000
        num Subjects
        0
      2. group Id
        FG001
        num Subjects
        0
      3. group Id
        FG002
        num Subjects
        0
      4. group Id
        FG003
        num Subjects
        0
      5. group Id
        FG004
        num Subjects
        0
      type
      NOT COMPLETED
    title
    Overall Study
recruitment Details
A total of 277 patients were recruited from 102 sites across 12 countries.
Complete source fields
groups
  1. description
    Patients with a deleterious BRCA (breast cancer susceptibility gene) mutation detected in their tumor.
    id
    FG000
    title
    BRCA Mutation
  2. description
    Patients with a deleterious ATM (ataxia telangiectasia mutated serine/threonine kinase) mutation detected in their tumor.
    id
    FG001
    title
    ATM Mutation
  3. description
    Patients with a deleterious CDK12 (Cyclin-dependent kinase 12) mutation detected in their tumor.
    id
    FG002
    title
    CDK12 Mutation
  4. description
    Patients with a deleterious CHEK2 (Checkpoint Kinase 2) mutation detected in their tumor.
    id
    FG003
    title
    CHEK2 Mutation
  5. description
    Patients with other deleterious HRR (homologous recombination repair) gene mutation detected in their tumor.
    id
    FG004
    title
    Other Gene Mutation
periods
  1. milestones
    1. achievements
      1. group Id
        FG000
        num Subjects
        172
      2. group Id
        FG001
        num Subjects
        59
      3. group Id
        FG002
        num Subjects
        14
      4. group Id
        FG003
        num Subjects
        7
      5. group Id
        FG004
        num Subjects
        25
      type
      STARTED
    2. achievements
      1. group Id
        FG000
        num Subjects
        172
      2. group Id
        FG001
        num Subjects
        59
      3. group Id
        FG002
        num Subjects
        14
      4. group Id
        FG003
        num Subjects
        7
      5. group Id
        FG004
        num Subjects
        25
      type
      COMPLETED
    3. achievements
      1. group Id
        FG000
        num Subjects
        0
      2. group Id
        FG001
        num Subjects
        0
      3. group Id
        FG002
        num Subjects
        0
      4. group Id
        FG003
        num Subjects
        0
      5. group Id
        FG004
        num Subjects
        0
      type
      NOT COMPLETED
    title
    Overall Study
recruitment Details
A total of 277 patients were recruited from 102 sites across 12 countries.

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice