TriangleNCT02823327 · OUTCOME
Differential Gene Expression Profile by RNA-Seq or GeneChip Assays
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- NUMBER
- Unit
- Number of overexpressed genes
- Interval / dispersion
- Not reported
- Time frame
- baseline
What was measured
The resultant data will be a subset of the whole analysis population due to RNAseq data availability. It will be assessed for quality, normalized, and then analyzed for differential gene expression. The Nanostring software nSolver will be used to do quality control, background subtraction, normalization, and analysis of the differential expression for RNA-sequencing data. Lastly, bioinformatic analysis approaches will be used to help make sense of possible biological links between the genes found to be differentially expressed between the sample groups that may be of prognostic significance. 19 Genes with p-value less than 0.05 were reported by the level of gene expression.
Analysis population: RNAseq data were available from 20 participants among 25 participants.
Groups in this outcome
Survival Less Than 2 Years With Available RNAseq Data
7 participants had RNAseq data among 8 participants with survival less than 2 years.
Survival More Than or Equal to 2 Years With Available RNAseq Data
13 participants had RNAseq data among 17 participants with survival more than or equal to 2 years.
| Group | Source count |
|---|---|
| Survival Less Than 2 Years With Available RNAseq Data | 7 |
| Survival More Than or Equal to 2 Years With Available RNAseq Data | 13 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Survival Less Than 2 Years With Available RNAseq Data | 4 | Not reported | Not reported | Not reported | Not reported |
| Survival More Than or Equal to 2 Years With Available RNAseq Data | 15 | Not reported | Not reported | Not reported | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- value
- 4
- group Id
- OG001
- value
- 15
- denoms
- counts
- group Id
- OG000
- value
- 7
- group Id
- OG001
- value
- 13
- units
- Participants
- description
- The resultant data will be a subset of the whole analysis population due to RNAseq data availability. It will be assessed for quality, normalized, and then analyzed for differential gene expression. The Nanostring software nSolver will be used to do quality control, background subtraction, normalization, and analysis of the differential expression for RNA-sequencing data. Lastly, bioinformatic analysis approaches will be used to help make sense of possible biological links between the genes found to be differentially expressed between the sample groups that may be of prognostic significance. 19 Genes with p-value less than 0.05 were reported by the level of gene expression.
- groups
- description
- 7 participants had RNAseq data among 8 participants with survival less than 2 years.
- id
- OG000
- title
- Survival Less Than 2 Years With Available RNAseq Data
- description
- 13 participants had RNAseq data among 17 participants with survival more than or equal to 2 years.
- id
- OG001
- title
- Survival More Than or Equal to 2 Years With Available RNAseq Data
- param Type
- NUMBER
- population Description
- RNAseq data were available from 20 participants among 25 participants.
- reporting Status
- POSTED
- time Frame
- baseline
- title
- Differential Gene Expression Profile by RNA-Seq or GeneChip Assays
- type
- PRIMARY
- unit Of Measure
- Number of overexpressed genes
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice