TriangleNCT02804750 · OUTCOME
Percentage of Participants With Hypertension Who Experience Improvement in Blood Pressure Following Treatment With CORT125134
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- NUMBER
- Unit
- Percentage of participants
- Interval / dispersion
- 95% Confidence Interval
- Time frame
- Group 1: Week 12 or last observation; Group 2: Week 16 or last observation
What was measured
Improvement in blood pressure was defined as a participant who experiences at least a 5 mmHg decrease in mean diastolic or systolic BP from baseline who has not taken an additional antihypertensive medication during the treatment period or increased the dosage of a concurrent antihypertensive medication.
Analysis population: All enrolled participants with hypertension at Baseline who received at least one dose of study drug and had at least one post-baseline assessment.
Groups in this outcome
Group 1: Low-dose Group
100 mg/day for 4 weeks in Period 1, then 150 mg/day for 4 weeks in Period 2, then 200 mg/day for 4 weeks in Period 3. Period 3 was followed by a 4-week follow-up period.
Group 2: High-dose Group
250 mg/day for 4 weeks in Period 1, then 300 mg/day for 4 weeks in Period 2, then 350 mg/day for 4 weeks in Period 3, then 400 mg/day for 4 weeks in Period 4. Period 4 was followed by a 4-week follow-up period.
| Group | Source count |
|---|---|
| Group 1: Low-dose Group | 12 |
| Group 2: High-dose Group | 11 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Group 1: Low-dose Group | 41.67 | Not reported | 15.17 | 72.33 | Not reported |
| Group 2: High-dose Group | 63.64 | Not reported | 30.79 | 89.07 | Not reported |
Complete source fields
- classes
- categories
- measurements
- group Id
- OG000
- lower Limit
- 15.17
- upper Limit
- 72.33
- value
- 41.67
- group Id
- OG001
- lower Limit
- 30.79
- upper Limit
- 89.07
- value
- 63.64
- denoms
- counts
- group Id
- OG000
- value
- 12
- group Id
- OG001
- value
- 11
- units
- Participants
- description
- Improvement in blood pressure was defined as a participant who experiences at least a 5 mmHg decrease in mean diastolic or systolic BP from baseline who has not taken an additional antihypertensive medication during the treatment period or increased the dosage of a concurrent antihypertensive medication.
- dispersion Type
- 95% Confidence Interval
- groups
- description
- 100 mg/day for 4 weeks in Period 1, then 150 mg/day for 4 weeks in Period 2, then 200 mg/day for 4 weeks in Period 3. Period 3 was followed by a 4-week follow-up period.
- id
- OG000
- title
- Group 1: Low-dose Group
- description
- 250 mg/day for 4 weeks in Period 1, then 300 mg/day for 4 weeks in Period 2, then 350 mg/day for 4 weeks in Period 3, then 400 mg/day for 4 weeks in Period 4. Period 4 was followed by a 4-week follow-up period.
- id
- OG001
- title
- Group 2: High-dose Group
- param Type
- NUMBER
- population Description
- All enrolled participants with hypertension at Baseline who received at least one dose of study drug and had at least one post-baseline assessment.
- reporting Status
- POSTED
- time Frame
- Group 1: Week 12 or last observation; Group 2: Week 16 or last observation
- title
- Percentage of Participants With Hypertension Who Experience Improvement in Blood Pressure Following Treatment With CORT125134
- type
- SECONDARY
- unit Of Measure
- Percentage of participants
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice