NCT02793544 · OUTCOME

Cumulative Incidence of Primary Graft Failure

HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide · Source last updated 2025-08-06

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: COUNT_OF_PARTICIPANTS
Unit: Participants
Interval / dispersion: Not reported
Time frame: 56 days post-transplant

What was measured

Lack of donor-derived neutrophil engraftment. The frequency of subjects experiencing primary graft failure by 56 days will be described.

Analysis population: Primary graft failure Lack of donor-derived neutrophil engraftment. The frequency of subjects experiencing primary graft failure by 56 days will be described. Transplanted participants surviving a minimum of 14 days post HCT and have complete data for both event status and event date.

Groups in this outcome

Myeloablative Conditioning (MAC)

Participants received one of three regimens: cyclophosphamide and total body irradiation; busulfan and cyclophosphamide; or fludarabine and busulfan

Reduced Intensity Conditioning (RIC)

Participants received one of two regimens: fludarabine, cyclophosphamide, and low-dose total body irradiation

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
Myeloablative Conditioning (MAC)	39
Reduced Intensity Conditioning (RIC)	40

Reported measurements

Source class 1

Values in Participants · Interval/dispersion: Not reported
Group	Value	Spread	Lower	Upper	Comment
Myeloablative Conditioning (MAC)	0	Not reported	Not reported	Not reported	Not reported
Reduced Intensity Conditioning (RIC)	3	Not reported	Not reported	Not reported	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
value
0
group Id
OG001
value
3

denoms

counts
group Id
OG000
value
39
group Id
OG001
value
40
units
Participants

description

Lack of donor-derived neutrophil engraftment. The frequency of subjects experiencing primary graft failure by 56 days will be described.

groups

description
Participants received one of three regimens: cyclophosphamide and total body irradiation; busulfan and cyclophosphamide; or fludarabine and busulfan
id
OG000
title
Myeloablative Conditioning (MAC)
description
Participants received one of two regimens: fludarabine, cyclophosphamide, and low-dose total body irradiation
id
OG001
title
Reduced Intensity Conditioning (RIC)

param Type

COUNT_OF_PARTICIPANTS

population Description

Primary graft failure Lack of donor-derived neutrophil engraftment. The frequency of subjects experiencing primary graft failure by 56 days will be described. Transplanted participants surviving a minimum of 14 days post HCT and have complete data for both event status and event date.

reporting Status

POSTED

time Frame

56 days post-transplant

title

Cumulative Incidence of Primary Graft Failure

type

SECONDARY

unit Of Measure

Participants

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice