NCT02767388 · OUTCOME

Change From Baseline CDA Amplitude at 1- and 3- Months

Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and Recovery · Source last updated 2023-09-29

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: MEAN
Unit: microvolts
Interval / dispersion: Standard Deviation
Time frame: Collected at Study Induction, 1 month after Study Induction, 3 months after Study Induction

What was measured

Electrophysiological component that measures online storage load

Analysis population: The number analyzed differed between rows due to participant dropout from Month-1 to Month-3. Differences in number analyzed and numbers in the Participant Flow module were due to patient dropout and either: (1) a minority of patients requesting not to complete testing; or (2) difficulties with electrophysiology or stimulus presentation equipment.

Groups in this outcome

HM - Chemotherapy

Study patients diagnosed with HM that are scheduled to receive chemotherapy treatment.

HM - No Chemotherapy

Study patients diagnosed with HM that are scheduled to receive non-chemotherapy treatment options.

Healthy Controls

Study participants that are demographically matched to HM study patients and meet all inclusion criteria

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
HM - Chemotherapy	7
HM - No Chemotherapy	9
Healthy Controls	11

Reported measurements

Change at 1-Month

Values in microvolts · Interval/dispersion: Standard Deviation
Group	Value	Spread	Lower	Upper	Comment
HM - Chemotherapy	.30	.29	Not reported	Not reported	Not reported
HM - No Chemotherapy	-.22	.91	Not reported	Not reported	Not reported
Healthy Controls	-.09	.55	Not reported	Not reported	Not reported

Change at 3-Month

Values in microvolts · Interval/dispersion: Standard Deviation
Group	Value	Spread	Lower	Upper	Comment
HM - Chemotherapy	-.34	.43	Not reported	Not reported	Not reported
HM - No Chemotherapy	-.10	.87	Not reported	Not reported	Not reported
Healthy Controls	-.27	.77	Not reported	Not reported	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
spread
.29
value
.30
group Id
OG001
spread
.91
value
-.22
group Id
OG002
spread
.55
value
-.09
title
Change at 1-Month
categories
measurements
group Id
OG000
spread
.43
value
-.34
group Id
OG001
spread
.87
value
-.10
group Id
OG002
spread
.77
value
-.27
title
Change at 3-Month

denoms

counts
group Id
OG000
value
7
group Id
OG001
value
9
group Id
OG002
value
11
units
Participants

description

Electrophysiological component that measures online storage load

dispersion Type

Standard Deviation

groups

description
Study patients diagnosed with HM that are scheduled to receive chemotherapy treatment.
id
OG000
title
HM - Chemotherapy
description
Study patients diagnosed with HM that are scheduled to receive non-chemotherapy treatment options.
id
OG001
title
HM - No Chemotherapy
description
Study participants that are demographically matched to HM study patients and meet all inclusion criteria
id
OG002
title
Healthy Controls

param Type

MEAN

population Description

The number analyzed differed between rows due to participant dropout from Month-1 to Month-3. Differences in number analyzed and numbers in the Participant Flow module were due to patient dropout and either: (1) a minority of patients requesting not to complete testing; or (2) difficulties with electrophysiology or stimulus presentation equipment.

reporting Status

POSTED

time Frame

Collected at Study Induction, 1 month after Study Induction, 3 months after Study Induction

title

Change From Baseline CDA Amplitude at 1- and 3- Months

type

PRIMARY

unit Of Measure

microvolts

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice