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NCT02599194 · OUTCOME

Change From Baseline in Standard Uptake Value Maximum (SUVmax) Post-treatment

18F-FSPG PET/CT for Cancer Patients on Therapy · Source last updated 2019-01-03

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
NUMBER
Unit
g/mL
Interval / dispersion
Not reported
Time frame
Baseline and up to 2 years

What was measured

Standard Uptake Values (SUVs) for the radiotracers labels 18F-FSPG and 18F-FDG were assessed in tumor tissues of study participants, before (baseline), and after therapeutic treatment. Time frame was specified by protocol as at baseline, and at the time of clinical assessments during individual patient regular medical care. The time of the post-treatment assessment was not otherwise explicitly defined but could be anytime within 2 years. The outcome is reported as the difference of means from baseline to post-treatment (a number without dispersion), for all lesions for which an SUVmax value was assessed. A negative result indicates less uptake of radiotracer suggesting a small volume of tumor.

Analysis population: Locations (ie, of lesions) that did not produce an SUVmax value either before or after treatment are omitted from the mean. Note that an analysis "mean of differences" would have a dispersion, but an analysis for "difference of means" is simply the delta (a number) between 2 measures of central tendency (mean), and does not have a dispersion.

Groups in this outcome

18F-FSPG and 18F-FDG Intragroup Comparision

Participants sequentially receive radioimaging agents 18F-FSPG and 18F-FDG IV followed by PET/CT scan with 60 minutes. 18F-FSPG: Administered intravenously (IV) 18F-FDG: Administered intravenously (IV)

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
18F-FSPG and 18F-FDG Intragroup Comparision7

Analysis denominator · Lesion locations assessed

GroupSource count
18F-FSPG and 18F-FDG Intragroup Comparision40

Reported measurements

18F-FSPG
Values in g/mL · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
18F-FSPG and 18F-FDG Intragroup Comparision-1.69Not reportedNot reportedNot reportedNot reported
18F-FDG
Values in g/mL · Interval/dispersion: Not reported
GroupValueSpreadLowerUpperComment
18F-FSPG and 18F-FDG Intragroup Comparision-0.64Not reportedNot reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        value
        -1.69
    title
    18F-FSPG
  2. categories
    1. measurements
      1. group Id
        OG000
        value
        -0.64
    title
    18F-FDG
denom Units Selected
Lesion locations assessed
denoms
  1. counts
    1. group Id
      OG000
      value
      7
    units
    Participants
  2. counts
    1. group Id
      OG000
      value
      40
    units
    Lesion locations assessed
description
Standard Uptake Values (SUVs) for the radiotracers labels 18F-FSPG and 18F-FDG were assessed in tumor tissues of study participants, before (baseline), and after therapeutic treatment. Time frame was specified by protocol as at baseline, and at the time of clinical assessments during individual patient regular medical care. The time of the post-treatment assessment was not otherwise explicitly defined but could be anytime within 2 years. The outcome is reported as the difference of means from baseline to post-treatment (a number without dispersion), for all lesions for which an SUVmax value was assessed. A negative result indicates less uptake of radiotracer suggesting a small volume of tumor.
groups
  1. description
    Participants sequentially receive radioimaging agents 18F-FSPG and 18F-FDG IV followed by PET/CT scan with 60 minutes. 18F-FSPG: Administered intravenously (IV) 18F-FDG: Administered intravenously (IV)
    id
    OG000
    title
    18F-FSPG and 18F-FDG Intragroup Comparision
param Type
NUMBER
population Description
Locations (ie, of lesions) that did not produce an SUVmax value either before or after treatment are omitted from the mean. Note that an analysis "mean of differences" would have a dispersion, but an analysis for "difference of means" is simply the delta (a number) between 2 measures of central tendency (mean), and does not have a dispersion.
reporting Status
POSTED
time Frame
Baseline and up to 2 years
title
Change From Baseline in Standard Uptake Value Maximum (SUVmax) Post-treatment
type
PRIMARY
type Units Analyzed
Lesion locations assessed
unit Of Measure
g/mL

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice