Participant flow

Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies · Source last updated 2025-04-24

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups

1. description

   RIC: Patients receive fludarabine phosphate IV on days -10 to -8 and cyclophosphamide IV on days -3 and -2. Patients also undergo TBI followed by a DLI on day -6. TRANSPLANT: Patients undergo CD34+ peripheral blood stem cell transplant on day 0. GVHD PROPHYLAXIS: Patients receive tacrolimus PO beginning day -1 with a taper initiated on day 42 and mycophenolate mofetil IV BID on days -1 to 28 in the absence of GVHD. Fludarabine: Given IV Total-Body Irradiation: Undergo TBI T Cell-Depleted Donor Lymphocyte Infusion: Undergo DLI Cyclophosphamide: Given IV Peripheral Blood Stem Cell Transplantation: Undergo PBSC transplant Allogeneic Hematopoietic Stem Cell Transplantation: Undergo PBSC transplant Tacrolimus: Given PO Mycophenolate mofetil: Given IV Laboratory Biomarker Analysis: Correlative studies

   id

   FG000

   title

   RIC HSCT, GVHD Prophylaxis

periods

1. milestones

   1. achievements

      1. group Id

         FG000

         num Subjects

         35

      type

      STARTED

   2. achievements

      1. group Id

         FG000

         num Subjects

         35

      type

      COMPLETED

   3. achievements

      1. group Id

         FG000

         num Subjects

         0

      type

      NOT COMPLETED

   title

   Overall Study

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice