NCT02470897 · OUTCOME

Change in Expanded Prostate Cancer Index Composite (EPIC) 26 Quality of Life Assessment: Urinary Irritative / Obstructive Sub-Domain

Stereotactic Body Radiation Therapy With Boost Using Urethral-Sparing Intensity-Modulated Radiation Therapy Planning in Treating Patients With Prostate Cancer · Source last updated 2026-10-13

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure: MEAN
Unit: score on a scale
Interval / dispersion: Standard Deviation
Time frame: at Baseline, 1 year, and 2 years

What was measured

The EPIC 26 assessment scores each of 5 domains on a scale of 1-100 where higher scores indicate higher satisfaction. Questionnaires will be performed prior to treatment, and one and two years after completion of treatment.

Analysis population: Some participants did not complete survey at all time points.

Groups in this outcome

Arm A (Moderate Dose SBRT With SIB)

Patients undergo 5 fractions of moderate dose SBRT with SIB every other day for 10 days following urethral-sparing IMRT planning. SBRT: 8.0Gy escalated dose Radiation Therapy Treatment Planning and Simulation: Undergo urethral-sparing IMRT planning SBRT: Undergo moderate dose SBRT with SIB

Arm B (Uniform Dose SBRT)

Patients undergo 5 fractions of uniform dose SBRT every other day for 10 days following urethral-sparing IMRT planning. SBRT: 7.5Gy conventional dose Radiation Therapy Treatment Planning and Simulation: Undergo urethral-sparing IMRT planning SBRT: Undergo uniform dose SBRT

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

Group	Source count
Arm A (Moderate Dose SBRT With SIB)	100
Arm B (Uniform Dose SBRT)	15

Reported measurements

Baseline

Analysis denominator · Participants

Group	Source count
Arm A (Moderate Dose SBRT With SIB)	96
Arm B (Uniform Dose SBRT)	12

Values in score on a scale · Interval/dispersion: Standard Deviation
Group	Value	Spread	Lower	Upper	Comment
Arm A (Moderate Dose SBRT With SIB)	86.46	11.81	Not reported	Not reported	Not reported
Arm B (Uniform Dose SBRT)	84.38	10.83	Not reported	Not reported	Not reported

1 year

Analysis denominator · Participants

Group	Source count
Arm A (Moderate Dose SBRT With SIB)	92
Arm B (Uniform Dose SBRT)	15

Values in score on a scale · Interval/dispersion: Standard Deviation
Group	Value	Spread	Lower	Upper	Comment
Arm A (Moderate Dose SBRT With SIB)	87.02	12.64	Not reported	Not reported	Not reported
Arm B (Uniform Dose SBRT)	84.58	15.82	Not reported	Not reported	Not reported

2 years

Analysis denominator · Participants

Group	Source count
Arm A (Moderate Dose SBRT With SIB)	90
Arm B (Uniform Dose SBRT)	12

Values in score on a scale · Interval/dispersion: Standard Deviation
Group	Value	Spread	Lower	Upper	Comment
Arm A (Moderate Dose SBRT With SIB)	90.28	9.23	Not reported	Not reported	Not reported
Arm B (Uniform Dose SBRT)	85.94	10.02	Not reported	Not reported	Not reported

Complete source fields

classes

categories
measurements
group Id
OG000
spread
11.81
value
86.46
group Id
OG001
spread
10.83
value
84.38
denoms
counts
group Id
OG000
value
96
group Id
OG001
value
12
units
Participants
title
Baseline
categories
measurements
group Id
OG000
spread
12.64
value
87.02
group Id
OG001
spread
15.82
value
84.58
denoms
counts
group Id
OG000
value
92
group Id
OG001
value
15
units
Participants
title
1 year
categories
measurements
group Id
OG000
spread
9.23
value
90.28
group Id
OG001
spread
10.02
value
85.94
denoms
counts
group Id
OG000
value
90
group Id
OG001
value
12
units
Participants
title
2 years

denoms

counts
group Id
OG000
value
100
group Id
OG001
value
15
units
Participants

description

dispersion Type

Standard Deviation

groups

description
Patients undergo 5 fractions of moderate dose SBRT with SIB every other day for 10 days following urethral-sparing IMRT planning. SBRT: 8.0Gy escalated dose Radiation Therapy Treatment Planning and Simulation: Undergo urethral-sparing IMRT planning SBRT: Undergo moderate dose SBRT with SIB
id
OG000
title
Arm A (Moderate Dose SBRT With SIB)
description
Patients undergo 5 fractions of uniform dose SBRT every other day for 10 days following urethral-sparing IMRT planning. SBRT: 7.5Gy conventional dose Radiation Therapy Treatment Planning and Simulation: Undergo urethral-sparing IMRT planning SBRT: Undergo uniform dose SBRT
id
OG001
title
Arm B (Uniform Dose SBRT)

param Type

MEAN

population Description

Some participants did not complete survey at all time points.

reporting Status

POSTED

time Frame

at Baseline, 1 year, and 2 years

title

Change in Expanded Prostate Cancer Index Composite (EPIC) 26 Quality of Life Assessment: Urinary Irritative / Obstructive Sub-Domain

type

SECONDARY

unit Of Measure

score on a scale

Download exact source JSON → · Snapshot ctgov-results-d643ffaf417bcef6d45eb5e0

Preserved source evidence · Not medical advice