NCT02451943 · BASELINE

Baseline characteristics

A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma · Source last updated 2025-07-15

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

counts
group Id
BG000
value
258
group Id
BG001
value
251
group Id
BG002
value
509
units
Participants

groups

description
75 milligrams per meter squared (mg/m\^2) doxorubicin administered intravenously (IV) on day 1 of each 21 day cycle for 8 cycles plus 20 milligrams per kilogram (mg/kg) dose of olaratumab administered IV on day 1 and day 8 of cycle 1 and 15 mg/kg olaratumab administered IV on day 1 and day 8 of cycles 2-8. Beginning with cycle 9, 15 mg/kg olaratumab administered IV on day 1 and day 8 of each subsequent 21 day cycle until documented progressive disease (PD) or discontinuation for any other reason.
id
BG000
title
Doxorubicin + Olaratumab
description
75 mg/m\^2 doxorubicin administered IV on day 1 of each 21 day cycle for 8 cycles plus placebo (equivalent volume) administered IV on day 1 and day 8 for 8 cycles. Beginning with cycle 9, placebo (equivalent volume) administered on days 1 and 8 of each subsequent 21 day cycle until PD or discontinuation for any other reason.
id
BG001
title
Doxorubicin + Placebo
description
Total of all reporting groups
id
BG002
title
Total

measures

classes
categories
measurements
group Id
BG000
spread
12.4
value
56.7
group Id
BG001
spread
11.6
value
57.1
group Id
BG002
spread
12.0
value
56.9
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
title
Age, Continuous
unit Of Measure
years
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
144
group Id
BG001
value
152
group Id
BG002
value
296
title
Female
measurements
group Id
BG000
value
114
group Id
BG001
value
99
group Id
BG002
value
213
title
Male
param Type
COUNT_OF_PARTICIPANTS
title
Sex: Female, Male
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
26
group Id
BG001
value
29
group Id
BG002
value
55
title
Hispanic or Latino
measurements
group Id
BG000
value
209
group Id
BG001
value
199
group Id
BG002
value
408
title
Not Hispanic or Latino
measurements
group Id
BG000
value
23
group Id
BG001
value
23
group Id
BG002
value
46
title
Unknown or Not Reported
param Type
COUNT_OF_PARTICIPANTS
title
Ethnicity (NIH/OMB)
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
3
group Id
BG002
value
6
title
American Indian or Alaska Native
measurements
group Id
BG000
value
50
group Id
BG001
value
48
group Id
BG002
value
98
title
Asian
measurements
group Id
BG000
value
1
group Id
BG001
value
0
group Id
BG002
value
1
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
12
group Id
BG001
value
2
group Id
BG002
value
14
title
Black or African American
measurements
group Id
BG000
value
186
group Id
BG001
value
193
group Id
BG002
value
379
title
White
measurements
group Id
BG000
value
5
group Id
BG001
value
4
group Id
BG002
value
9
title
More than one race
measurements
group Id
BG000
value
1
group Id
BG001
value
1
group Id
BG002
value
2
title
Unknown or Not Reported
param Type
COUNT_OF_PARTICIPANTS
title
Race (NIH/OMB)
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
69
group Id
BG001
value
73
group Id
BG002
value
142
title
United States
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
8
group Id
BG002
value
15
title
Russia
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
0
group Id
BG002
value
3
title
Austria
categories
measurements
group Id
BG000
value
15
group Id
BG001
value
13
group Id
BG002
value
28
title
South Korea
categories
measurements
group Id
BG000
value
8
group Id
BG001
value
6
group Id
BG002
value
14
title
Netherlands
categories
measurements
group Id
BG000
value
4
group Id
BG001
value
3
group Id
BG002
value
7
title
Sweden
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
0
group Id
BG002
value
2
title
Brazil
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
2
group Id
BG002
value
5
title
Poland
categories
measurements
group Id
BG000
value
17
group Id
BG001
value
18
group Id
BG002
value
35
title
France
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
4
group Id
BG002
value
7
title
Argentina
categories
measurements
group Id
BG000
value
9
group Id
BG001
value
11
group Id
BG002
value
20
title
Hungary
categories
measurements
group Id
BG000
value
23
group Id
BG001
value
22
group Id
BG002
value
45
title
Japan
param Type
COUNT_OF_PARTICIPANTS
title
Region of Enrollment
unit Of Measure
Participants

population Description

All randomized participants.

Complete source fields

denoms

counts
group Id
BG000
value
258
group Id
BG001
value
251
group Id
BG002
value
509
units
Participants

groups

description
75 milligrams per meter squared (mg/m\^2) doxorubicin administered intravenously (IV) on day 1 of each 21 day cycle for 8 cycles plus 20 milligrams per kilogram (mg/kg) dose of olaratumab administered IV on day 1 and day 8 of cycle 1 and 15 mg/kg olaratumab administered IV on day 1 and day 8 of cycles 2-8. Beginning with cycle 9, 15 mg/kg olaratumab administered IV on day 1 and day 8 of each subsequent 21 day cycle until documented progressive disease (PD) or discontinuation for any other reason.
id
BG000
title
Doxorubicin + Olaratumab
description
75 mg/m\^2 doxorubicin administered IV on day 1 of each 21 day cycle for 8 cycles plus placebo (equivalent volume) administered IV on day 1 and day 8 for 8 cycles. Beginning with cycle 9, placebo (equivalent volume) administered on days 1 and 8 of each subsequent 21 day cycle until PD or discontinuation for any other reason.
id
BG001
title
Doxorubicin + Placebo
description
Total of all reporting groups
id
BG002
title
Total

measures

classes
categories
measurements
group Id
BG000
spread
12.4
value
56.7
group Id
BG001
spread
11.6
value
57.1
group Id
BG002
spread
12.0
value
56.9
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
title
Age, Continuous
unit Of Measure
years
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
144
group Id
BG001
value
152
group Id
BG002
value
296
title
Female
measurements
group Id
BG000
value
114
group Id
BG001
value
99
group Id
BG002
value
213
title
Male
param Type
COUNT_OF_PARTICIPANTS
title
Sex: Female, Male
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
26
group Id
BG001
value
29
group Id
BG002
value
55
title
Hispanic or Latino
measurements
group Id
BG000
value
209
group Id
BG001
value
199
group Id
BG002
value
408
title
Not Hispanic or Latino
measurements
group Id
BG000
value
23
group Id
BG001
value
23
group Id
BG002
value
46
title
Unknown or Not Reported
param Type
COUNT_OF_PARTICIPANTS
title
Ethnicity (NIH/OMB)
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
3
group Id
BG002
value
6
title
American Indian or Alaska Native
measurements
group Id
BG000
value
50
group Id
BG001
value
48
group Id
BG002
value
98
title
Asian
measurements
group Id
BG000
value
1
group Id
BG001
value
0
group Id
BG002
value
1
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
12
group Id
BG001
value
2
group Id
BG002
value
14
title
Black or African American
measurements
group Id
BG000
value
186
group Id
BG001
value
193
group Id
BG002
value
379
title
White
measurements
group Id
BG000
value
5
group Id
BG001
value
4
group Id
BG002
value
9
title
More than one race
measurements
group Id
BG000
value
1
group Id
BG001
value
1
group Id
BG002
value
2
title
Unknown or Not Reported
param Type
COUNT_OF_PARTICIPANTS
title
Race (NIH/OMB)
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
69
group Id
BG001
value
73
group Id
BG002
value
142
title
United States
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
8
group Id
BG002
value
15
title
Russia
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
0
group Id
BG002
value
3
title
Austria
categories
measurements
group Id
BG000
value
15
group Id
BG001
value
13
group Id
BG002
value
28
title
South Korea
categories
measurements
group Id
BG000
value
8
group Id
BG001
value
6
group Id
BG002
value
14
title
Netherlands
categories
measurements
group Id
BG000
value
4
group Id
BG001
value
3
group Id
BG002
value
7
title
Sweden
categories
measurements
group Id
BG000
value
2
group Id
BG001
value
0
group Id
BG002
value
2
title
Brazil
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
2
group Id
BG002
value
5
title
Poland
categories
measurements
group Id
BG000
value
17
group Id
BG001
value
18
group Id
BG002
value
35
title
France
categories
measurements
group Id
BG000
value
3
group Id
BG001
value
4
group Id
BG002
value
7
title
Argentina
categories
measurements
group Id
BG000
value
9
group Id
BG001
value
11
group Id
BG002
value
20
title
Hungary
categories
measurements
group Id
BG000
value
23
group Id
BG001
value
22
group Id
BG002
value
45
title
Japan
param Type
COUNT_OF_PARTICIPANTS
title
Region of Enrollment
unit Of Measure
Participants

population Description

All randomized participants.

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice