NCT02411448 · BASELINE

Baseline characteristics

A Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic NSCLC (RELAY) · Source last updated 2026-01-16

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

counts
group Id
BG000
value
14
group Id
BG001
value
224
group Id
BG002
value
225
group Id
BG003
value
463
units
Participants

groups

description
Part A: 10 milligrams per kilogram (mg/kg) ramucirumab administered every 2 weeks intravenously (IV) in combination with 150 mg erlotinib daily orally. Participants may continue to receive treatment until discontinuation criteria are met.
id
BG000
title
Part A: Ramucirumab + Erlotinib
description
Part B: 10 mg/kg ramucirumab administered every 2 weeks IV in combination with 150 mg erlotinib daily orally. Participants may continue to receive treatment until discontinuation criteria are met.
id
BG001
title
Part B: Ramucirumab+ Erlotinib
description
Part B: Placebo administered every 2 weeks IV in combination with 150 mg erlotinib daily orally. Participants may continue to receive treatment until discontinuation criteria are met.
id
BG002
title
Part B: Placebo+ Erlotinib
description
Total of all reporting groups
id
BG003
title
Total

measures

classes
categories
measurements
group Id
BG000
spread
13.2
value
67.6
comment
Row represents Part A data only.
group Id
BG001
spread
NA
value
NA
comment
Row represents Part A data only.
group Id
BG002
spread
NA
value
NA
group Id
BG003
spread
13
value
67.6
title
Part A
categories
measurements
comment
Row represents Part B data only.
group Id
BG000
spread
NA
value
NA
group Id
BG001
spread
10.2
value
63.7
group Id
BG002
spread
10.6
value
62.9
group Id
BG003
spread
10.4
value
63.3
title
Part B
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
title
Age, Continuous
unit Of Measure
years
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
11
group Id
BG001
value
141
group Id
BG002
value
142
group Id
BG003
value
294
title
Female
measurements
group Id
BG000
value
3
group Id
BG001
value
83
group Id
BG002
value
83
group Id
BG003
value
169
title
Male
param Type
COUNT_OF_PARTICIPANTS
title
Sex: Female, Male
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
13
group Id
BG002
value
10
group Id
BG003
value
23
title
Hispanic or Latino
measurements
group Id
BG000
value
1
group Id
BG001
value
150
group Id
BG002
value
160
group Id
BG003
value
311
title
Not Hispanic or Latino
measurements
group Id
BG000
value
13
group Id
BG001
value
61
group Id
BG002
value
55
group Id
BG003
value
129
title
Unknown or Not Reported
param Type
COUNT_OF_PARTICIPANTS
title
Ethnicity (NIH/OMB)
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
1
group Id
BG003
value
1
title
American Indian or Alaska Native
measurements
group Id
BG000
value
7
group Id
BG001
value
172
group Id
BG002
value
174
group Id
BG003
value
353
title
Asian
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
1
group Id
BG003
value
1
title
Black or African American
measurements
group Id
BG000
value
7
group Id
BG001
value
52
group Id
BG002
value
48
group Id
BG003
value
107
title
White
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
More than one race
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
1
group Id
BG003
value
1
title
Unknown or Not Reported
param Type
COUNT_OF_PARTICIPANTS
title
Race (NIH/OMB)
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
2
group Id
BG002
value
0
group Id
BG003
value
2
title
Romania
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
9
group Id
BG002
value
6
group Id
BG003
value
15
title
Hong Kong
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
7
group Id
BG002
value
2
group Id
BG003
value
9
title
United States
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
106
group Id
BG002
value
105
group Id
BG003
value
218
title
Japan
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
4
group Id
BG002
value
3
group Id
BG003
value
7
title
United Kingdom
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
23
group Id
BG002
value
19
group Id
BG003
value
49
title
Spain
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
2
group Id
BG003
value
2
title
Canada
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
25
group Id
BG002
value
29
group Id
BG003
value
54
title
South Korea
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
3
group Id
BG002
value
4
group Id
BG003
value
7
title
Turkey
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
26
group Id
BG002
value
30
group Id
BG003
value
56
title
Taiwan
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
8
group Id
BG002
value
12
group Id
BG003
value
20
title
Italy
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
4
group Id
BG002
value
7
group Id
BG003
value
11
title
France
param Type
COUNT_OF_PARTICIPANTS
title
Region of Enrollment
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
166
group Id
BG002
value
170
group Id
BG003
value
343
title
East Asia
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
58
group Id
BG002
value
55
group Id
BG003
value
120
title
Other*
description
\* Geographic region "Other" includes Canada, France, Germany, Italy, Romania, Spain, Turkey, US, UK.
param Type
COUNT_OF_PARTICIPANTS
title
Geographic Region
unit Of Measure
Participants

population Description

All enrolled participants. Part C data will be reported after study completion.

Complete source fields

denoms

counts
group Id
BG000
value
14
group Id
BG001
value
224
group Id
BG002
value
225
group Id
BG003
value
463
units
Participants

groups

description
Part A: 10 milligrams per kilogram (mg/kg) ramucirumab administered every 2 weeks intravenously (IV) in combination with 150 mg erlotinib daily orally. Participants may continue to receive treatment until discontinuation criteria are met.
id
BG000
title
Part A: Ramucirumab + Erlotinib
description
Part B: 10 mg/kg ramucirumab administered every 2 weeks IV in combination with 150 mg erlotinib daily orally. Participants may continue to receive treatment until discontinuation criteria are met.
id
BG001
title
Part B: Ramucirumab+ Erlotinib
description
Part B: Placebo administered every 2 weeks IV in combination with 150 mg erlotinib daily orally. Participants may continue to receive treatment until discontinuation criteria are met.
id
BG002
title
Part B: Placebo+ Erlotinib
description
Total of all reporting groups
id
BG003
title
Total

measures

classes
categories
measurements
group Id
BG000
spread
13.2
value
67.6
comment
Row represents Part A data only.
group Id
BG001
spread
NA
value
NA
comment
Row represents Part A data only.
group Id
BG002
spread
NA
value
NA
group Id
BG003
spread
13
value
67.6
title
Part A
categories
measurements
comment
Row represents Part B data only.
group Id
BG000
spread
NA
value
NA
group Id
BG001
spread
10.2
value
63.7
group Id
BG002
spread
10.6
value
62.9
group Id
BG003
spread
10.4
value
63.3
title
Part B
dispersion Type
STANDARD_DEVIATION
param Type
MEAN
title
Age, Continuous
unit Of Measure
years
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
11
group Id
BG001
value
141
group Id
BG002
value
142
group Id
BG003
value
294
title
Female
measurements
group Id
BG000
value
3
group Id
BG001
value
83
group Id
BG002
value
83
group Id
BG003
value
169
title
Male
param Type
COUNT_OF_PARTICIPANTS
title
Sex: Female, Male
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
13
group Id
BG002
value
10
group Id
BG003
value
23
title
Hispanic or Latino
measurements
group Id
BG000
value
1
group Id
BG001
value
150
group Id
BG002
value
160
group Id
BG003
value
311
title
Not Hispanic or Latino
measurements
group Id
BG000
value
13
group Id
BG001
value
61
group Id
BG002
value
55
group Id
BG003
value
129
title
Unknown or Not Reported
param Type
COUNT_OF_PARTICIPANTS
title
Ethnicity (NIH/OMB)
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
1
group Id
BG003
value
1
title
American Indian or Alaska Native
measurements
group Id
BG000
value
7
group Id
BG001
value
172
group Id
BG002
value
174
group Id
BG003
value
353
title
Asian
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
Native Hawaiian or Other Pacific Islander
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
1
group Id
BG003
value
1
title
Black or African American
measurements
group Id
BG000
value
7
group Id
BG001
value
52
group Id
BG002
value
48
group Id
BG003
value
107
title
White
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
0
group Id
BG003
value
0
title
More than one race
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
1
group Id
BG003
value
1
title
Unknown or Not Reported
param Type
COUNT_OF_PARTICIPANTS
title
Race (NIH/OMB)
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
2
group Id
BG002
value
0
group Id
BG003
value
2
title
Romania
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
9
group Id
BG002
value
6
group Id
BG003
value
15
title
Hong Kong
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
7
group Id
BG002
value
2
group Id
BG003
value
9
title
United States
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
106
group Id
BG002
value
105
group Id
BG003
value
218
title
Japan
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
4
group Id
BG002
value
3
group Id
BG003
value
7
title
United Kingdom
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
23
group Id
BG002
value
19
group Id
BG003
value
49
title
Spain
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
0
group Id
BG002
value
2
group Id
BG003
value
2
title
Canada
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
25
group Id
BG002
value
29
group Id
BG003
value
54
title
South Korea
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
3
group Id
BG002
value
4
group Id
BG003
value
7
title
Turkey
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
26
group Id
BG002
value
30
group Id
BG003
value
56
title
Taiwan
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
8
group Id
BG002
value
12
group Id
BG003
value
20
title
Italy
categories
measurements
group Id
BG000
value
0
group Id
BG001
value
4
group Id
BG002
value
7
group Id
BG003
value
11
title
France
param Type
COUNT_OF_PARTICIPANTS
title
Region of Enrollment
unit Of Measure
Participants
calculate Pct
false
classes
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
166
group Id
BG002
value
170
group Id
BG003
value
343
title
East Asia
categories
measurements
group Id
BG000
value
7
group Id
BG001
value
58
group Id
BG002
value
55
group Id
BG003
value
120
title
Other*
description
\* Geographic region "Other" includes Canada, France, Germany, Italy, Romania, Spain, Turkey, US, UK.
param Type
COUNT_OF_PARTICIPANTS
title
Geographic Region
unit Of Measure
Participants

population Description

All enrolled participants. Part C data will be reported after study completion.

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice