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NCT02393859 · OUTCOME

Pharmacokinetics: Clearance (CL) (Blinatumomab Arm Only)

Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL) · Source last updated 2026-06-26

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
MEAN
Unit
L/hr/m^2
Interval / dispersion
Standard Deviation
Time frame
Day 1: at least 10 hours after infusion start and up to 24 hours; Day 15

Analysis population: PK Analysis Set: participants who received any infusion of blinatumomab and had at least one PK sample collected.

Groups in this outcome

Blinatumomab

One 4-week cycle of blinatumomab 15 μg/m\^2/day as a continuous intravenous infusion (CIVI).

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Blinatumomab45

Reported measurements

Source class 1
Values in L/hr/m^2 · Interval/dispersion: Standard Deviation
GroupValueSpreadLowerUpperComment
Blinatumomab1.140.836Not reportedNot reportedNot reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        spread
        0.836
        value
        1.14
denoms
  1. counts
    1. group Id
      OG000
      value
      45
    units
    Participants
dispersion Type
Standard Deviation
groups
  1. description
    One 4-week cycle of blinatumomab 15 μg/m\^2/day as a continuous intravenous infusion (CIVI).
    id
    OG000
    title
    Blinatumomab
param Type
MEAN
population Description
PK Analysis Set: participants who received any infusion of blinatumomab and had at least one PK sample collected.
reporting Status
POSTED
time Frame
Day 1: at least 10 hours after infusion start and up to 24 hours; Day 15
title
Pharmacokinetics: Clearance (CL) (Blinatumomab Arm Only)
type
SECONDARY
unit Of Measure
L/hr/m^2

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice