TriangleNCT02362035 · OUTCOME
Overall Survival
Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.
- Measure
- MEDIAN
- Unit
- Months
- Interval / dispersion
- 95% Confidence Interval
- Time frame
- 104 weeks
What was measured
The time from the first dose date of acalabrutinib or pembrolizumab until date of death due to any cause
Analysis population: All participants in this study received both study drugs and were therefore analyzed together as a single treatment arm. Participants receiving the different regimens were not analyzed separately by regimen, as the study was designed to assess the the combination study treatment.
Groups in this outcome
Acalabrutinib + Pembrolizumab
All participants in this study received both study drugs and were therefore analysed together as a single treatment arm. Participants receiving the different regimens were not analysed separately by regimen, as the study was designed to assess the safety of the combination study treatment. The study included N=161 participants who received both acalabrutinib and pembrolizumab and are summarized together (from First stage safety lead-in and Second stage expansion). Stage 3 (additional expansion in subjects with Myelofibrosis) was planned but not conducted.
| Group | Source count |
|---|---|
| Acalabrutinib + Pembrolizumab | 161 |
Reported measurements
Source class 1
| Group | Value | Spread | Lower | Upper | Comment |
|---|---|---|---|---|---|
| Acalabrutinib + Pembrolizumab | 50.4 | Not reported | 26.2 | NA | NA= not estimable. The NA of the 95% upper bound was calculated from the median. Since the upper limit of the KM curve hadn't reached 50%, there is no estimate for the upper confidence limit on the median. Therefore it's NA = not estimable. |
Complete source fields
- classes
- categories
- measurements
- comment
- NA= not estimable. The NA of the 95% upper bound was calculated from the median. Since the upper limit of the KM curve hadn't reached 50%, there is no estimate for the upper confidence limit on the median. Therefore it's NA = not estimable.
- group Id
- OG000
- lower Limit
- 26.2
- upper Limit
- NA
- value
- 50.4
- denoms
- counts
- group Id
- OG000
- value
- 161
- units
- Participants
- description
- The time from the first dose date of acalabrutinib or pembrolizumab until date of death due to any cause
- dispersion Type
- 95% Confidence Interval
- groups
- description
- All participants in this study received both study drugs and were therefore analysed together as a single treatment arm. Participants receiving the different regimens were not analysed separately by regimen, as the study was designed to assess the safety of the combination study treatment. The study included N=161 participants who received both acalabrutinib and pembrolizumab and are summarized together (from First stage safety lead-in and Second stage expansion). Stage 3 (additional expansion in subjects with Myelofibrosis) was planned but not conducted.
- id
- OG000
- title
- Acalabrutinib + Pembrolizumab
- param Type
- MEDIAN
- population Description
- All participants in this study received both study drugs and were therefore analyzed together as a single treatment arm. Participants receiving the different regimens were not analyzed separately by regimen, as the study was designed to assess the the combination study treatment.
- reporting Status
- POSTED
- time Frame
- 104 weeks
- title
- Overall Survival
- type
- SECONDARY
- unit Of Measure
- Months
Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f
Preserved source evidence · Not medical advice