Baseline characteristics

Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation · Source last updated 2017-05-30

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      6

   units

   Participants

groups

1. description

   Participants undergo a conditioning regimen with cyclophosphamide, fludarabine, aldesleukin (interleukin-2), natural killer cell therapy, anti-thymocyte globulin, rituximab, thiotepa, and melphalan prior to transplantation of T-cell depleted HPC transplant on day 0 and CD45RA-depleted HPC transplant on day 1. Beginning Day 6 post-transplant, patients receive G-CSF daily until ANC recovers to normal level. Cyclophosphamide: Given intravenously (IV) Fludarabine: Given IV G-CSF: Given IV or subcutaneously (SQ) Interleukin-2: Given SQ Melphalan: Given IV Thiotepa: Given IV Rituximab: Given IV Natural killer cell therapy: Given IV T-cell depleted HPC transplant: T-cell depleted hematopoietic stem cells will be infused on day 0. CD45RA-depleted HPC transplant: CD45RA depleted stem cells will be infused on day 1.

   id

   BG000

   title

   Participants

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            spread

            5.5

            value

            12.6

   dispersion Type

   STANDARD_DEVIATION

   param Type

   MEAN

   title

   Age, Continuous

   unit Of Measure

   years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            lower Limit

            6.7

            upper Limit

            19.5

            value

            12.2

      title

      Age, Median

   dispersion Type

   FULL_RANGE

   param Type

   MEDIAN

   title

   Age, Customized

   unit Of Measure

   years

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            2

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            4

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

4. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            1

      title

      Not otherwise specified Spanish, Hispanic, Latino

   2. categories

      1. measurements

         1. group Id

            BG000

            value

            5

      title

      Non Spanish speaking, Non Hispanic

   param Type

   NUMBER

   title

   Race/Ethnicity, Customized

   unit Of Measure

   participants

5. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            2

      title

      AML with 11q23/MLL abnormalities

   2. categories

      1. measurements

         1. group Id

            BG000

            value

            1

      title

      AML, multilineage dysplasia with prior MDS

   3. categories

      1. measurements

         1. group Id

            BG000

            value

            2

      title

      AML, not otherwise specified

   4. categories

      1. measurements

         1. group Id

            BG000

            value

            1

      title

      AML, without maturation

   description

   AML = acute myeloid leukemia; MLL = myeloid-lymphoid leukemia; MDS = myelodysplastic syndrome

   param Type

   NUMBER

   title

   Primary Diagnosis

   unit Of Measure

   participants

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Preserved source evidence · Not medical advice