Skip to content
Triangle logo TriangleGet started
← Full study record

NCT02231749 · BASELINE

Baseline characteristics

Nivolumab Combined With Ipilimumab Versus Sunitinib in Previously Untreated Advanced or Metastatic Renal Cell Carcinoma (CheckMate 214) · Source last updated 2026-05-27

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms
  1. counts
    1. group Id
      BG000
      value
      550
    2. group Id
      BG001
      value
      546
    3. group Id
      BG002
      value
      1096
    units
    Participants
groups
  1. description
    Nivolumab 3 mg/kg combined with Ipilimumab 1 mg/kg solutions intravenously every 3 weeks for 4 doses then Nivolumab 3 mg/kg solutions intravenously every 2 weeks until documented disease progression, discontinuation due to toxicity, withdrawal of consent or the study ends
    id
    BG000
    title
    Nivolumab + Ipilimumab
  2. description
    Sunitinib 50 mg capsules by mouth once daily for 4 weeks then 2 weeks off, continuously until documented disease progression, discontinuation due to toxicity, withdrawal of consent or the study ends After completion of final analysis eligible participants may switch from receiving Sunitinib to receiving Nivolumab 3 mg/kg IV combined with Ipilimumab 1 mg/kg IV every 3 weeks for 4 doses then Nivolumab 240mg flat dose IV every 2 weeks
    id
    BG001
    title
    Sunitinib
  3. description
    Total of all reporting groups
    id
    BG002
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          9.76
          value
          61.1
        2. group Id
          BG001
          spread
          10.10
          value
          60.7
        3. group Id
          BG002
          spread
          9.93
          value
          60.9
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    population Description
    All Randomized
    title
    Age, Continuous
    unit Of Measure
    Years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          137
        2. group Id
          BG001
          value
          151
        3. group Id
          BG002
          value
          288
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          413
        2. group Id
          BG001
          value
          395
        3. group Id
          BG002
          value
          808
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    population Description
    All Randomized Participants
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          12
        2. group Id
          BG001
          value
          17
        3. group Id
          BG002
          value
          29
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          264
        2. group Id
          BG001
          value
          253
        3. group Id
          BG002
          value
          517
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          274
        2. group Id
          BG001
          value
          276
        3. group Id
          BG002
          value
          550
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          486
        2. group Id
          BG001
          value
          483
        3. group Id
          BG002
          value
          969
        title
        White
      2. measurements
        1. group Id
          BG000
          value
          7
        2. group Id
          BG001
          value
          6
        3. group Id
          BG002
          value
          13
        title
        Black or African American
      3. measurements
        1. group Id
          BG000
          value
          46
        2. group Id
          BG001
          value
          47
        3. group Id
          BG002
          value
          93
        title
        Asian
      4. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        title
        American Indian or Alaska Native
      5. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        title
        Native Hawaiian or Pacific Islander
      6. measurements
        1. group Id
          BG000
          value
          10
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          20
        title
        Other
      7. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        title
        Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    population Description
    All Randomized Participants
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
population Description
All Randomized Participants
Complete source fields
denoms
  1. counts
    1. group Id
      BG000
      value
      550
    2. group Id
      BG001
      value
      546
    3. group Id
      BG002
      value
      1096
    units
    Participants
groups
  1. description
    Nivolumab 3 mg/kg combined with Ipilimumab 1 mg/kg solutions intravenously every 3 weeks for 4 doses then Nivolumab 3 mg/kg solutions intravenously every 2 weeks until documented disease progression, discontinuation due to toxicity, withdrawal of consent or the study ends
    id
    BG000
    title
    Nivolumab + Ipilimumab
  2. description
    Sunitinib 50 mg capsules by mouth once daily for 4 weeks then 2 weeks off, continuously until documented disease progression, discontinuation due to toxicity, withdrawal of consent or the study ends After completion of final analysis eligible participants may switch from receiving Sunitinib to receiving Nivolumab 3 mg/kg IV combined with Ipilimumab 1 mg/kg IV every 3 weeks for 4 doses then Nivolumab 240mg flat dose IV every 2 weeks
    id
    BG001
    title
    Sunitinib
  3. description
    Total of all reporting groups
    id
    BG002
    title
    Total
measures
  1. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          spread
          9.76
          value
          61.1
        2. group Id
          BG001
          spread
          10.10
          value
          60.7
        3. group Id
          BG002
          spread
          9.93
          value
          60.9
    dispersion Type
    STANDARD_DEVIATION
    param Type
    MEAN
    population Description
    All Randomized
    title
    Age, Continuous
    unit Of Measure
    Years
  2. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          137
        2. group Id
          BG001
          value
          151
        3. group Id
          BG002
          value
          288
        title
        Female
      2. measurements
        1. group Id
          BG000
          value
          413
        2. group Id
          BG001
          value
          395
        3. group Id
          BG002
          value
          808
        title
        Male
    param Type
    COUNT_OF_PARTICIPANTS
    population Description
    All Randomized Participants
    title
    Sex: Female, Male
    unit Of Measure
    Participants
  3. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          12
        2. group Id
          BG001
          value
          17
        3. group Id
          BG002
          value
          29
        title
        Hispanic or Latino
      2. measurements
        1. group Id
          BG000
          value
          264
        2. group Id
          BG001
          value
          253
        3. group Id
          BG002
          value
          517
        title
        Not Hispanic or Latino
      3. measurements
        1. group Id
          BG000
          value
          274
        2. group Id
          BG001
          value
          276
        3. group Id
          BG002
          value
          550
        title
        Unknown or Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    title
    Ethnicity (NIH/OMB)
    unit Of Measure
    Participants
  4. classes
    1. categories
      1. measurements
        1. group Id
          BG000
          value
          486
        2. group Id
          BG001
          value
          483
        3. group Id
          BG002
          value
          969
        title
        White
      2. measurements
        1. group Id
          BG000
          value
          7
        2. group Id
          BG001
          value
          6
        3. group Id
          BG002
          value
          13
        title
        Black or African American
      3. measurements
        1. group Id
          BG000
          value
          46
        2. group Id
          BG001
          value
          47
        3. group Id
          BG002
          value
          93
        title
        Asian
      4. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        title
        American Indian or Alaska Native
      5. measurements
        1. group Id
          BG000
          value
          0
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          0
        title
        Native Hawaiian or Pacific Islander
      6. measurements
        1. group Id
          BG000
          value
          10
        2. group Id
          BG001
          value
          10
        3. group Id
          BG002
          value
          20
        title
        Other
      7. measurements
        1. group Id
          BG000
          value
          1
        2. group Id
          BG001
          value
          0
        3. group Id
          BG002
          value
          1
        title
        Not Reported
    param Type
    COUNT_OF_PARTICIPANTS
    population Description
    All Randomized Participants
    title
    Race/Ethnicity, Customized
    unit Of Measure
    Participants
population Description
All Randomized Participants

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Not medical advice