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NCT02205801 · REGISTRY CONDITION SEARCH

Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy

Found through the registry condition index, not selected as a treatment recommendation. This discovery collection was restricted to studies with posted results.

Phase
NA
Status at capture
COMPLETED
Registry last update
2018-03-09

We aim to study the effect of local anesthetic when used in conjunction with general anesthesia during thyroidectomy or parathyroidectomy. We hypothesize there is equivalent pain control between bilateral superficial cervical plexus block and local wound infiltration when used in conjunction with a general anesthetic.

Open the original ClinicalTrials.gov record → · Download preserved record

What did the study report?

Outcomes, safety and baseline populations are separate source sections. Quality-of-life measures appear under their original outcome titles.

flow

Participant flow

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baseline

Baseline characteristics

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outcome · POSTED

Intraoperative Fentanyl Administration

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outcome · POSTED

Post Operative Pain

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outcome · POSTED

Post Operative Nausea Score

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outcome · POSTED

Total Pain Medication Utilization

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adverse events

Adverse events

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more info

Limitations, agreements, and source contact

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Who could take part
eligibility Criteria
Inclusion Criteria: * Patient ≥ 18 years old * Surgical indication for parathyroidectomy or thyroidectomy Exclusion Criteria: * Patients \< 18 years old * Patient with history of chronic opioid use * Patient with chronic pain syndromes * Patient with allergy to marcaine
healthy Volunteers
false
minimum Age
18 Years
sex
ALL
std Ages
  1. ADULT
  2. OLDER_ADULT
Treatment arms and interventions
arm Groups
  1. description
    After induction of general anesthesia the surgeon will perform a bilateral superficial cervical plexus block using 0.25% Marcaine.
    intervention Names
    1. Procedure: Superficial Cervical Plexus Block
    2. Drug: Marcaine
    label
    superficial cervical block, active
    type
    ACTIVE_COMPARATOR
  2. description
    After induction of general anesthesia the surgeon will perform local wound infiltration using 0.9% Saline.
    intervention Names
    1. Procedure: Local Wound Infiltration
    2. Drug: 0.9% saline
    label
    local wound infiltration, placebo
    type
    PLACEBO_COMPARATOR
  3. description
    After induction of general anesthesia the surgeon will perform a local wound infiltration using 0.25% Marcaine.
    intervention Names
    1. Procedure: Local Wound Infiltration
    2. Drug: Marcaine
    label
    local wound infiltration, active
    type
    ACTIVE_COMPARATOR
  4. description
    After induction of general anesthesia the surgeon will perform a bilateral superficial cervical plexus block using 0.9% saline.
    intervention Names
    1. Procedure: Superficial Cervical Plexus Block
    2. Drug: 0.9% saline
    label
    superficial cervical block, placebo
    type
    PLACEBO_COMPARATOR
interventions
  1. arm Group Labels
    1. superficial cervical block, active
    2. superficial cervical block, placebo
    description
    0.25% Marcaine is injected lateral to the sternocleidomastoid bilaterally (10mL on each side) after induction of anesthesia and prior to incision and scheduled thyroidectomy or parathyroidectomy.
    name
    Superficial Cervical Plexus Block
    type
    PROCEDURE
  2. arm Group Labels
    1. local wound infiltration, active
    2. local wound infiltration, placebo
    description
    0.50% Marcaine is injected at the site of incision (10mL) after induction of anesthesia and prior to incision and scheduled thyroidectomy or parathyroidectomy.
    name
    Local Wound Infiltration
    type
    PROCEDURE
  3. arm Group Labels
    1. local wound infiltration, placebo
    2. superficial cervical block, placebo
    name
    0.9% saline
    type
    DRUG
  4. arm Group Labels
    1. local wound infiltration, active
    2. superficial cervical block, active
    name
    Marcaine
    type
    DRUG
Study design
allocation
RANDOMIZED
intervention Model
PARALLEL
masking Info
masking
DOUBLE
who Masked
  1. PARTICIPANT
  2. CARE_PROVIDER
primary Purpose
TREATMENT
Enrollment
count
36
type
ACTUAL
Registered outcome plans (not posted results)
primary Outcomes
  1. description
    The total amount of Fentanyl administered during the procedure will be recorded.
    measure
    Intraoperative Fentanyl Administration
    time Frame
    During the procedure
secondary Outcomes
  1. description
    Pain scores will either be verbally reported to nursing and recorded or reported on a questionnaire. Back of neck pain scores range 0-10, throat pain scores range 0-9, incisional pain scores range 0-9 (zero means no pain and 9 or 10 means severe pain).
    measure
    Post Operative Pain
    time Frame
    At four hour after operation
  2. description
    Nausea scores will either be verbally reported to nursing and recorded or reported on a questionnaire. The scores range 0-9 (zero means no symptom and 9 means "very severe").
    measure
    Post Operative Nausea Score
    time Frame
    At 2 weeks after operation
  3. description
    Total operative opioid dosages administered converted to effective mg of Hydromorphine.
    measure
    Total Pain Medication Utilization
    time Frame
    At follow up appointment 1-2 weeks postoperatively
Full study description
brief Summary
We aim to study the effect of local anesthetic when used in conjunction with general anesthesia during thyroidectomy or parathyroidectomy. We hypothesize there is equivalent pain control between bilateral superficial cervical plexus block and local wound infiltration when used in conjunction with a general anesthetic.
Source references
Source notices and limitations
    Discovery and provenance
    1. release id
      ctgov-registry-1336d216cbd1bbff780dac70
      edge id
      nct-edge-97da3eac6c9ba6caade9
      requested nct id
      NCT02205801
      primary nct id
      NCT02205801
      source kind
      ctgov_condition_query
      source record id
      Source null
      source file sha256
      2b4988b513f0b70e7c49c0c10cabf5241c1231b8e29e89b78dc9406bd8749c8a
      payload sha256
      55ec54b06933f3f0b26f15ba90f0fb83ba3e9a67e65686bc4f19daa311789117
      payload
      clinical indication matching status
      condition_index_match_asserted_by_registry_not_reviewed
      end exclusive
      true
      id
      nct-edge-97da3eac6c9ba6caade9
      link basis
      returned_by_explicit_condition_and_posted_results_filter_query
      nct id
      NCT02205801
      occurrences
      1. context exact
        NCT02205801
        end
        11
        exact text
        NCT02205801
        start
        0
      offset unit
      unicode_code_points
      query cond
      Parathyroid Cancer
      query disease state id
      ds-parathyroid-cancer
      source file
      /Users/arunverma/Documents/ChatGPT/Cancer Statistics Website/research-data/2026-09-10/clinicaltrials-condition/round-0000/raw/cond-parathyroid-cancer-000.json
      source file sha256
      2b4988b513f0b70e7c49c0c10cabf5241c1231b8e29e89b78dc9406bd8749c8a
      source json pointer
      /studies/7/protocolSection/identificationModule/nctId
      source kind
      ctgov_condition_query
      source record id
      Source null
      source string basis
      parsed_JSON_string_unmodified
      source string sha256
      22a50da769a36cae07bd7c7915df3663c41bf3dfacf15fc693a77bf903f6ce95

    Preserved source evidence · Not medical advice