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NCT02169791 · OUTCOME

Day 30 CD33 Donor Chimerism

Nonmyeloablative Haploidentical Transplant Followed by MLN9708 · Source last updated 2021-09-02

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

Measure
MEDIAN
Unit
percentage of chimerism
Interval / dispersion
Full Range
Time frame
30 days

What was measured

To measure CD33 donor chimerism at Day 30

Groups in this outcome

Haploidentical Transplant

All patients will receive a haploidentical donor transplant using a conditioning regimen of Fludarabine (Flu), cyclophosphamide (cy) and total body irradiation (TBI) followed by MLN9708. MLN9708: MLN9708 will be given weekly x 3 weeks every 28 day cycles, for up to 12 cycles starting at D+5 post-transplant.

Group identifiers and denominators belong to this outcome only. They may differ in another outcome or in safety reporting.

Analysis denominator · Participants

GroupSource count
Haploidentical Transplant25

Reported measurements

Source class 1
Values in percentage of chimerism · Interval/dispersion: Full Range
GroupValueSpreadLowerUpperComment
Haploidentical Transplant100Not reported93100Not reported
Complete source fields
classes
  1. categories
    1. measurements
      1. group Id
        OG000
        lower Limit
        93
        upper Limit
        100
        value
        100
denoms
  1. counts
    1. group Id
      OG000
      value
      25
    units
    Participants
description
To measure CD33 donor chimerism at Day 30
dispersion Type
Full Range
groups
  1. description
    All patients will receive a haploidentical donor transplant using a conditioning regimen of Fludarabine (Flu), cyclophosphamide (cy) and total body irradiation (TBI) followed by MLN9708. MLN9708: MLN9708 will be given weekly x 3 weeks every 28 day cycles, for up to 12 cycles starting at D+5 post-transplant.
    id
    OG000
    title
    Haploidentical Transplant
param Type
MEDIAN
reporting Status
POSTED
time Frame
30 days
title
Day 30 CD33 Donor Chimerism
type
SECONDARY
unit Of Measure
percentage of chimerism

Download exact source JSON → · Snapshot ctgov-results-25a395029948b04d52b1253f

Preserved source evidence · Not medical advice