Participant flow

A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread · Source last updated 2025-11-06

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

groups

1. description

   Nivolumab 3 mg/kg

   id

   FG000

   title

   Cohort 1: Nivolumab Monotherapy

2. description

   Nivolumab 3 mg/kg + Ipilimumab 1 mg/kg

   id

   FG001

   title

   Cohort 2: Nivolumab 3 mg/kg + Ipilimumab 1 mg/kg

3. description

   Nivolumab 3 mg/kg Q2W with Ipilimumab 1 mg/kg twice in six weeks Q6W

   id

   FG002

   title

   Cohort 3: Nivolumab 3 mg/kg Q2W with Ipilimumab 1 mg/kg Q6W

4. description

   Nivolumab 3 mg/kg Q2W with Ipilimumab 1 mg/kg Q6W

   id

   FG003

   title

   MSS: Nivolumab 3 mg/kg Q2W with Ipilimumab 1 mg/kg Q6W

5. description

   Nivolumab 1 mg/kg + Ipilimumab 3 mg/kg

   id

   FG004

   title

   Non-MSI-H: Nivolumab 1 mg/kg + Ipilimumab 3 mg/kg

6. description

   Nivolumab 1 mg/kg + Ipilimumab 1 mg/kg

   id

   FG005

   title

   Non-MSI-H: Nivolumab 1 mg/kg + Ipilimumab 1 mg/kg

7. description

   Nivolumab 3 mg/kg + Ipilimumab 1 mg/kg + Cobimetinib 60 mg

   id

   FG006

   title

   Cohort 4: Nivolumab 3 mg/kg + Ipilimumab 1 mg/kg + Cobimetinib 60 mg

8. description

   Nivolumab 240 mg + BMS-986016 80 mg

   id

   FG007

   title

   Cohort 5: Nivolumab 240 mg + BMS-986016 80 mg

9. description

   Nivolumab FD + Daratumumab 16 mg/kg

   id

   FG008

   title

   Cohort 6: Nivolumab FD + Daratumumab 16 mg/kg

periods

1. drop Withdraws

   1. reasons

      1. group Id

         FG000

         num Subjects

         36

      2. group Id

         FG001

         num Subjects

         42

      3. group Id

         FG002

         num Subjects

         8

      4. group Id

         FG003

         num Subjects

         5

      5. group Id

         FG004

         num Subjects

         6

      6. group Id

         FG005

         num Subjects

         3

      7. group Id

         FG006

         num Subjects

         23

      8. group Id

         FG007

         num Subjects

         20

      9. group Id

         FG008

         num Subjects

         43

      type

      Disease Progression

   2. reasons

      1. group Id

         FG000

         num Subjects

         10

      2. group Id

         FG001

         num Subjects

         18

      3. group Id

         FG002

         num Subjects

         7

      4. group Id

         FG003

         num Subjects

         4

      5. group Id

         FG004

         num Subjects

         3

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         2

      8. group Id

         FG007

         num Subjects

         5

      9. group Id

         FG008

         num Subjects

         0

      type

      Study Drug Toxicity

   3. reasons

      1. group Id

         FG000

         num Subjects

         2

      2. group Id

         FG001

         num Subjects

         5

      3. group Id

         FG002

         num Subjects

         6

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         1

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         4

      8. group Id

         FG007

         num Subjects

         4

      9. group Id

         FG008

         num Subjects

         1

      type

      Adverse event unrelated to study drug

   4. reasons

      1. group Id

         FG000

         num Subjects

         7

      2. group Id

         FG001

         num Subjects

         7

      3. group Id

         FG002

         num Subjects

         4

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         1

      8. group Id

         FG007

         num Subjects

         1

      9. group Id

         FG008

         num Subjects

         0

      type

      Participant request to discontinue study treatment

   5. reasons

      1. group Id

         FG000

         num Subjects

         3

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         0

      type

      Participant withdrew consent

   6. reasons

      1. group Id

         FG000

         num Subjects

         13

      2. group Id

         FG001

         num Subjects

         38

      3. group Id

         FG002

         num Subjects

         19

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         10

      9. group Id

         FG008

         num Subjects

         0

      type

      Maximum clinical benefit

   7. reasons

      1. group Id

         FG000

         num Subjects

         3

      2. group Id

         FG001

         num Subjects

         7

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         1

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         9

      9. group Id

         FG008

         num Subjects

         0

      type

      Other reason

   8. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         1

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         1

      9. group Id

         FG008

         num Subjects

         0

      type

      Death

   9. reasons

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         1

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         0

      type

      Administrative reasons by sponsor

   10. reasons

       1. group Id

          FG000

          num Subjects

          0

       2. group Id

          FG001

          num Subjects

          0

       3. group Id

          FG002

          num Subjects

          1

       4. group Id

          FG003

          num Subjects

          0

       5. group Id

          FG004

          num Subjects

          0

       6. group Id

          FG005

          num Subjects

          0

       7. group Id

          FG006

          num Subjects

          0

       8. group Id

          FG007

          num Subjects

          0

       9. group Id

          FG008

          num Subjects

          0

       type

       Lost to Follow-up

   milestones

   1. achievements

      1. group Id

         FG000

         num Subjects

         74

      2. group Id

         FG001

         num Subjects

         119

      3. group Id

         FG002

         num Subjects

         45

      4. group Id

         FG003

         num Subjects

         10

      5. group Id

         FG004

         num Subjects

         10

      6. group Id

         FG005

         num Subjects

         3

      7. group Id

         FG006

         num Subjects

         30

      8. group Id

         FG007

         num Subjects

         50

      9. group Id

         FG008

         num Subjects

         44

      type

      STARTED

   2. achievements

      1. group Id

         FG000

         num Subjects

         0

      2. group Id

         FG001

         num Subjects

         0

      3. group Id

         FG002

         num Subjects

         0

      4. group Id

         FG003

         num Subjects

         0

      5. group Id

         FG004

         num Subjects

         0

      6. group Id

         FG005

         num Subjects

         0

      7. group Id

         FG006

         num Subjects

         0

      8. group Id

         FG007

         num Subjects

         0

      9. group Id

         FG008

         num Subjects

         0

      type

      COMPLETED

   3. achievements

      1. group Id

         FG000

         num Subjects

         74

      2. group Id

         FG001

         num Subjects

         119

      3. group Id

         FG002

         num Subjects

         45

      4. group Id

         FG003

         num Subjects

         10

      5. group Id

         FG004

         num Subjects

         10

      6. group Id

         FG005

         num Subjects

         3

      7. group Id

         FG006

         num Subjects

         30

      8. group Id

         FG007

         num Subjects

         50

      9. group Id

         FG008

         num Subjects

         44

      type

      NOT COMPLETED

   title

   Overall Study

Download exact source JSON → · Snapshot ctgov-results-191f4516d4760045304b24a0

Preserved source evidence · Independent clinical review pending · Not medical advice