Baseline characteristics

Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy. · Source last updated 2021-07-20

Results reported by the registry submitting party. Population, time horizon, units and missing values must be read together.

denoms

1. counts

   1. group Id

      BG000

      value

      74

   2. group Id

      BG001

      value

      75

   3. group Id

      BG002

      value

      149

   units

   Participants

groups

1. description

   Ruxolitinib at a starting dose of 10 mg twice a day (bid). Dose was adjusted based on efficacy and safety parameters up to a maximum dose of 25 mg bid

   id

   BG000

   title

   Ruxolitinib

2. description

   Best Available Therapy as selected by the investigator from: Hydroxyurea, Pegylated-Interferon (IFN/PEG-IFN), pipobroman, anagrelide, IMIDs, or observation. Participants randomized to BAT who did not respond by Week 28 were eligible to crossover and start treatment with ruxolitinib

   id

   BG001

   title

   Best Available Therapy (BAT)

3. description

   Total of all reporting groups

   id

   BG002

   title

   Total

measures

1. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            spread

            11.31

            value

            62.8

         2. group Id

            BG001

            spread

            11.12

            value

            66.0

         3. group Id

            BG002

            spread

            11.29

            value

            64.4

   dispersion Type

   STANDARD_DEVIATION

   param Type

   MEAN

   title

   Age, Continuous

   unit Of Measure

   years

2. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            35

         2. group Id

            BG001

            value

            28

         3. group Id

            BG002

            value

            63

         title

         Female

      2. measurements

         1. group Id

            BG000

            value

            39

         2. group Id

            BG001

            value

            47

         3. group Id

            BG002

            value

            86

         title

         Male

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Sex: Female, Male

   unit Of Measure

   Participants

3. classes

   1. categories

      1. measurements

         1. group Id

            BG000

            value

            67

         2. group Id

            BG001

            value

            66

         3. group Id

            BG002

            value

            133

         title

         Caucasian

      2. measurements

         1. group Id

            BG000

            value

            4

         2. group Id

            BG001

            value

            5

         3. group Id

            BG002

            value

            9

         title

         Asian

      3. measurements

         1. group Id

            BG000

            value

            3

         2. group Id

            BG001

            value

            4

         3. group Id

            BG002

            value

            7

         title

         Other

   param Type

   COUNT_OF_PARTICIPANTS

   title

   Race/Ethnicity, Customized

   unit Of Measure

   Participants

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Preserved source evidence · Not medical advice